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Jinsai Shang
Jinsai Shang
Guangzhou Laboratory, School of Basic Medical Sciences, Guangzhou Medical University
Zweryfikowany adres z scripps.edu - Strona główna
Tytuł
Cytowane przez
Cytowane przez
Rok
Fe-catalysed oxidative C–H functionalization/C–S bond formation
H Wang, L Wang, J Shang, X Li, H Wang, J Gui, A Lei
Chemical communications 48 (1), 76-78, 2012
2392012
REV-ERBα regulates TH17 cell development and autoimmunity
M Amir, S Chaudhari, R Wang, S Campbell, SA Mosure, LB Chopp, Q Lu, ...
Cell reports 25 (13), 3733-3749. e8, 2018
892018
Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPARγ
J Shang, R Brust, SA Mosure, J Bass, P Munoz-Tello, H Lin, TS Hughes, ...
Elife 7, e43320, 2018
672018
Identification of a binding site for unsaturated fatty acids in the orphan nuclear receptor Nurr1
IMS de Vera, PK Giri, P Munoz-Tello, R Brust, J Fuhrmann, ...
ACS chemical biology 11 (7), 1795-1799, 2016
642016
Defining a conformational ensemble that directs activation of PPARγ
IM Chrisman, MD Nemetchek, IMS De Vera, J Shang, Z Heidari, Y Long, ...
Nature communications 9 (1), 1794, 2018
622018
A structural mechanism for directing corepressor-selective inverse agonism of PPARγ
R Brust, J Shang, J Fuhrmann, SA Mosure, J Bass, A Cano, Z Heidari, ...
Nature communications 9 (1), 4687, 2018
552018
Synergistic regulation of coregulator/nuclear receptor interaction by ligand and DNA
IMS de Vera, J Zheng, S Novick, J Shang, TS Hughes, R Brust, ...
Structure 25 (10), 1506-1518. e4, 2017
512017
A molecular switch regulating transcriptional repression and activation of PPARγ
J Shang, SA Mosure, J Zheng, R Brust, J Bass, A Nichols, LA Solt, ...
Nature Communications 11 (1), 956, 2020
492020
Defining a canonical ligand-binding pocket in the orphan nuclear receptor Nurr1
IMS de Vera, P Munoz-Tello, J Zheng, V Dharmarajan, DP Marciano, ...
Structure 27 (1), 66-77. e5, 2019
432019
CAR directs T cell adaptation to bile acids in the small intestine
ML Chen, X Huang, H Wang, C Hegner, Y Liu, J Shang, A Eliason, H Diao, ...
Nature 593 (7857), 147-151, 2021
412021
Structural basis of altered potency and efficacy displayed by a major in vivo metabolite of the antidiabetic PPARγ drug pioglitazone
SA Mosure, J Shang, J Eberhardt, R Brust, J Zheng, PR Griffin, S Forli, ...
Journal of medicinal chemistry 62 (4), 2008-2023, 2019
312019
Chemical crosslinking mass spectrometry reveals the conformational landscape of the activation helix of PPARγ; a model for ligand-dependent antagonism
J Zheng, C Corzo, MR Chang, J Shang, VQ Lam, R Brust, AL Blayo, ...
Structure 26 (11), 1431-1439. e6, 2018
272018
Structural mechanism underlying ligand binding and activation of PPARγ
J Shang, DJ Kojetin
Structure 29 (9), 940-950. e4, 2021
232021
Probing the Complex Binding Modes of the PPARγ Partial Agonist 2-Chloro-N-(3-chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluoromethyl …
TS Hughes, J Shang, R Brust, IMS de Vera, J Fuhrmann, C Ruiz, ...
Journal of medicinal chemistry 59 (22), 10335-10341, 2016
232016
Quantitative structural assessment of graded receptor agonism
J Shang, R Brust, PR Griffin, TM Kameneck, DJ Kojetin
Proceedings of the National Academy of Sciences 116 (44), 22179-22188, 2019
202019
Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERBβ
SA Mosure, TS Strutzenberg, J Shang, P Munoz-Tello, LA Solt, PR Griffin, ...
Science advances 7 (5), eabc6479, 2021
182021
Structure of the FP domain of Fbxo7 reveals a novel mode of protein–protein interaction
J Shang, G Wang, Y Yang, X Huang, Z Du
Acta Crystallographica Section D: Biological Crystallography 70 (1), 155-164, 2014
112014
The FP domains of PI31 and Fbxo7 have the same protein fold but very different modes of protein–protein interaction
J Shang, X Huang, Z Du
Journal of Biomolecular Structure and Dynamics 33 (7), 1528-1538, 2015
82015
The FP Domains of PI31 and Fbxo7 have the same Protein Fold but very Different Modes of Protein–Protein Interaction
ZD Jinsai Shang, Xiaolan Huang
The FASEB Journal 29 (1), Supplement 883.4, 2015
8*2015
Expression, purification and crystallization of the FP domain of the human F-box protein Fbxo7
J Shang, G Wang, Y Yang, X Huang, Z Du
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013
52013
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