Restoration of replication fork stability in BRCA1-and BRCA2-deficient cells by inactivation of SNF2-family fork remodelers A Taglialatela, S Alvarez, G Leuzzi, V Sannino, L Ranjha, JW Huang, ... Molecular cell 68 (2), 414-430. e8, 2017 | 345 | 2017 |
Replication fork slowing and reversal upon DNA damage require PCNA polyubiquitination and ZRANB3 DNA translocase activity M Vujanovic, J Krietsch, MC Raso, N Terraneo, R Zellweger, JA Schmid, ... Molecular cell 67 (5), 882-890. e5, 2017 | 233 | 2017 |
Functional interrogation of DNA damage response variants with base editing screens R Cuella-Martin, SB Hayward, X Fan, X Chen, JW Huang, A Taglialatela, ... Cell 184 (4), 1081-1097. e19, 2021 | 171 | 2021 |
Stimulation of CRISPR-mediated homology-directed repair by an engineered RAD18 variant TS Nambiar, P Billon, G Diedenhofen, SB Hayward, A Taglialatela, K Cai, ... Nature Communications 10 (1), 3395, 2019 | 118 | 2019 |
REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps A Taglialatela, G Leuzzi, V Sannino, R Cuella-Martin, JW Huang, ... Molecular cell 81 (19), 4008-4025. e7, 2021 | 100 | 2021 |
The BRCT domains of the BRCA1 and BARD1 tumor suppressors differentially regulate homology-directed repair and stalled fork protection D Billing, M Horiguchi, F Wu-Baer, A Taglialatela, G Leuzzi, SA Nanez, ... Molecular cell 72 (1), 127-139. e8, 2018 | 75 | 2018 |
Replication stress impairs chromosome segregation and preimplantation development in human embryos KL Palmerola, S Amrane, A De Los Angeles, S Xu, N Wang, J de Pinho, ... Cell 185 (16), 2988-3007. e20, 2022 | 46 | 2022 |
MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage JW Huang, A Acharya, A Taglialatela, TS Nambiar, R Cuella-Martin, ... Nature communications 11 (1), 2948, 2020 | 35 | 2020 |
Time for remodeling: SNF2-family DNA translocases in replication fork metabolism and human disease SA Joseph, A Taglialatela, G Leuzzi, JW Huang, R Cuella-Martin, A Ciccia DNA repair 95, 102943, 2020 | 26 | 2020 |
Strand annealing and motor driven activities of SMARCAL1 and ZRANB3 are stimulated by RAD51 and the paralog complex S Halder, L Ranjha, A Taglialatela, A Ciccia, P Cejka Nucleic Acids Research 50 (14), 8008-8022, 2022 | 18 | 2022 |
CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one-carbon metabolism in breast cancer MG Filippone, D Gaglio, R Bonfanti, FA Tucci, E Ceccacci, R Pennisi, ... Nature communications 13 (1), 2642, 2022 | 16 | 2022 |
Partial loss-of-function mutations in GINS4 lead to NK cell deficiency with neutropenia MI Conte, MC Poli, A Taglialatela, G Leuzzi, IK Chinn, SA Salinas, ... JCI insight 7 (21), 2022 | 10 | 2022 |
Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination JM Schvartzman, G Forsyth, H Walch, W Chatila, A Taglialatela, BJ Lee, ... Molecular Cell 83 (13), 2347-2356. e8, 2023 | 5 | 2023 |
SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion G Leuzzi, A Vasciaveo, A Taglialatela, X Chen, TM Firestone, ... Cell 187 (4), 861-881. e32, 2024 | 3 | 2024 |
Partial loss of function mutations in GINS4 lead to natural killer cell deficiency with neutropenia M Conte, A Taglialatela, G Leuzzi, I Chinn, S Salinas, C Poli, LV Espinoza, ... Journal of Allergy and Clinical Immunology 149 (2), AB321, 2022 | 1 | 2022 |
HATtracting nucleases to stalled forks G Leuzzi, A Taglialatela, A Ciccia Molecular Cell 80 (2), 177-180, 2020 | 1 | 2020 |
BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks D Georgieva, N Wang, A Taglialatela, S Jerabek, CR Reczek, PX Lim, ... Cell reports 43 (4), 2024 | | 2024 |
Abstract PR009: SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion G Leuzzi, A Vasciaveo, A Taglialatela, X Chen, TM Firestone, ... Cancer Research 84 (1_Supplement), PR009-PR009, 2024 | | 2024 |
Abstract B023: SMARCAL1 is a novel candidate therapeutic target for ALT-positive osteosarcoma A Taglialatela, X Chen, ZF Khan, F Dela Cruz, D Shivi, D Oswald, ... Cancer Research 84 (1_Supplement), B023-B023, 2024 | | 2024 |
Abstract PR010: Understanding extrachromosomal telomere generation in ALT cancers J Lee, J Lee, EJ Sohn, A Taglialatela, RJ O’Sullivan, A Ciccia, J Min Cancer Research 84 (1_Supplement), PR010-PR010, 2024 | | 2024 |