Follow
Tríona Ní Chonghaile
Title
Cited by
Cited by
Year
Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy
TN Chonghaile, KA Sarosiek, TT Vo, JA Ryan, A Tammareddi, ...
Science 334 (6059), 1129-1133, 2011
6282011
Bcl-2 family on guard at the ER
E Szegezdi, DC MacDonald, T Ní Chonghaile, S Gupta, A Samali
American Journal of Physiology-Cell Physiology 296 (5), C941-C953, 2009
3192009
Mimicking the BH3 domain to kill cancer cells
TN Chonghaile, A Letai
Oncogene 27 (1), S149-S157, 2008
3042008
Maturation Stage of T-cell Acute Lymphoblastic Leukemia Determines BCL-2 versus BCL-XL Dependence and Sensitivity to ABT-199
TN Chonghaile, JE Roderick, C Glenfield, J Ryan, SE Sallan, ...
Cancer discovery 4 (9), 1074-1087, 2014
2612014
Mitochondria: gatekeepers of response to chemotherapy
KA Sarosiek, TN Chonghaile, A Letai
Trends in cell biology 23 (12), 612-619, 2013
1812013
BH3 profiling identifies heterogeneous dependency on Bcl-2 family members in multiple myeloma and predicts sensitivity to BH3 mimetics
C Touzeau, J Ryan, J Guerriero, P Moreau, TN Chonghaile, S Le Gouill, ...
Leukemia 30 (3), 761-764, 2016
1552016
MLL-rearranged acute lymphoblastic leukemias activate BCL-2 through H3K79 methylation and are sensitive to the BCL-2-specific antagonist ABT-199
JM Benito, L Godfrey, K Kojima, L Hogdal, M Wunderlich, H Geng, I Marzo, ...
Cell reports 13 (12), 2715-2727, 2015
1422015
P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment
AK Azab, P Quang, F Azab, C Pitsillides, B Thompson, T Chonghaile, ...
Blood, The Journal of the American Society of Hematology 119 (6), 1468-1478, 2012
1302012
Distinct mechanisms of cardiomyocyte apoptosis induced by doxorubicin and hypoxia converge on mitochondria and are inhibited by Bcl‐xL
JLV Reeve, E Szegezdi, SE Logue, TN Chonghaile, T O’Brien, T Ritter, ...
Journal of cellular and molecular medicine 11 (3), 509-520, 2007
1072007
Therapeutic rationale to target highly expressed CDK7 conferring poor outcomes in triple-negative breast cancer
B Li, T Ni Chonghaile, Y Fan, SF Madden, R Klinger, AE O'Connor, ...
Cancer research 77 (14), 3834-3845, 2017
892017
Targeting the miR-221–222/PUMA/BAK/BAX pathway abrogates dexamethasone resistance in multiple myeloma
JJ Zhao, ZB Chu, Y Hu, J Lin, Z Wang, M Jiang, M Chen, X Wang, Y Kang, ...
Cancer research 75 (20), 4384-4397, 2015
852015
Cell and Molecular Determinants of In Vivo Efficacy of the BH3 Mimetic ABT-263 against Pediatric Acute Lymphoblastic Leukemia Xenografts
S Suryani, H Carol, TN Chonghaile, V Frismantas, C Sarmah, L High, ...
Clinical cancer research 20 (17), 4520-4531, 2014
802014
The emerging role of non-traditional ubiquitination in oncogenic pathways
L Dwane, WM Gallagher, TN Chonghaile, DP O'Connor
Journal of Biological Chemistry 292 (9), 3543-3551, 2017
532017
PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia
IM Ariës, K Bodaar, SA Karim, TN Chonghaile, L Hinze, MA Burns, ...
Journal of Experimental Medicine 215 (12), 3094-3114, 2018
482018
Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer
CM Dowling, KER Hollinshead, A Di Grande, J Pritchard, H Zhang, ...
Science advances 7 (3), eabc4897, 2021
372021
Dexamethasone inhibits apoptosis in C6 glioma cells through increased expression of Bcl-XL
T Ní Chonghaile, CG Concannon, E Szegezdi, AM Gorman, A Samali
Apoptosis 11, 1247-1255, 2006
372006
Maturation stage of T-cell acute lymphoblastic leukemia determines BCL-2 versus BCL-XL dependence and sensitivity to ABT-199. Cancer Discov. 2014; 4: 1074–1087. doi: 10.1158 …
TN Chonghaile, JE Roderick, C Glenfield, J Ryan, SE Sallan, ...
CD-14-0353.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 2022
322022
The anti-inflammatory compound candesartan cilexetil improves neurological outcomes in a mouse model of neonatal hypoxia
S Quinlan, P Merino-Serrais, A Di Grande, H Dussmann, JHM Prehn, ...
Frontiers in Immunology 10, 459413, 2019
192019
The anti-inflammatory compound candesartan cilexetil improves neurological outcomes in a mouse model of neonatal hypoxia
S Quinlan, P Merino-Serrais, A Di Grande, H Dussmann, JHM Prehn, ...
Frontiers in Immunology 10, 459413, 2019
192019
A functional genomic screen identifies the deubiquitinase USP11 as a novel transcriptional regulator of ERα in breast cancer
Cancer Research, 2020
182020
The system can't perform the operation now. Try again later.
Articles 1–20