| VOLSURF: A Tool for Drug ADME‐Properties Prediction G Cruciani, M Meniconi, E Carosati, I Zamora, R Mannhold Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and …, 2003 | 42 | 2003 |
| Exploiting differences in caspase-2 and-3 S2 subsites for selectivity: Structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 … MC Maillard, FA Brookfield, SM Courtney, FM Eustache, MJ Gemkow, ... Bioorganic & medicinal chemistry 19 (19), 5833-5851, 2011 | 39 | 2011 |
| Fragment-based screening identifies molecules targeting the substrate-binding ankyrin repeat domains of tankyrase K Pollock, M Liu, M Zaleska, M Meniconi, M Pfuhl, I Collins, S Guettler Scientific Reports 9 (1), 19130, 2019 | 26 | 2019 |
| Insights into phenylalanine derivatives recognition of VLA-4 integrin: from a pharmacophoric study to 3D-QSAR and molecular docking analyses A Macchiarulo, G Costantino, M Meniconi, K Pleban, G Ecker, D Bellocchi, ... Journal of chemical information and computer sciences 44 (5), 1829-1839, 2004 | 19 | 2004 |
| The role of electrostatic interaction in the molecular recognition of selective agonists to metabotropic glutamate receptors A Macchiarulo, G Costantino, R Sbaglia, S Aiello, M Meniconi, ... Proteins: Structure, Function, and Bioinformatics 50 (4), 609-619, 2003 | 18 | 2003 |
| Optimizing shape complementarity enables the discovery of potent tricyclic BCL6 inhibitors OA Davis, KMJ Cheung, A Brennan, MG Lloyd, MJ Rodrigues, OA Pierrat, ... Journal of Medicinal Chemistry 65 (12), 8169-8190, 2022 | 12 | 2022 |
| Into deep water: Optimizing BCL6 inhibitors by growing into a solvated pocket MG Lloyd, R Huckvale, KMJ Cheung, MJ Rodrigues, GW Collie, ... Journal of Medicinal Chemistry 64 (23), 17079-17097, 2021 | 11 | 2021 |
| canSAR chemistry registration and standardization pipeline D Dolciami, E Villasclaras-Fernandez, C Kannas, M Meniconi, ... Journal of Cheminformatics 14 (1), 28, 2022 | 10 | 2022 |
| Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo R Huckvale, AC Harnden, KMJ Cheung, OA Pierrat, R Talbot, GM Box, ... Journal of Medicinal Chemistry 65 (12), 8191-8207, 2022 | 5 | 2022 |
| Heteroaryl derivatives as sepiapterin reductase inhibitors MJ Tebbe, HV ATTON, C AVERY, SM Bromidge, M KERRY, AK Kotey, ... | 4 | 2018 |
| Bcl6 inhibitors BR BELLENIE, KMJ CHEUNG, OA DAVIS, S Hoelder, R HUCKVALE, ... | 1 | 2022 |
| BCL6 inhibitors BR Bellenie, KMJ Cheung, OA Davis, S Hoelder, R Huckvale, G Collie, ... US Patent 11,512,095, 2022 | 1 | 2022 |
| Heteroaryl inhibitors of PAD4 R Devraj, G Kumaravel, H Atton, E Beaumont, E Gadouleau, L Gleave, ... US Patent 11,198,681, 2021 | 1 | 2021 |
| Heteroaryl inhibitors of PAD4 R Devraj, G Kumaravel, C Lecci, PL Loke, M Meniconi, NJT Monck, ... US Patent 11,026,937, 2021 | 1 | 2021 |
| Covalent inhibitors of PAD4 EJ Beaumont, R Devraj, PS Kerry, G Kumaravel, PL Loke, M Meniconi, ... US Patent 10,703,741, 2020 | 1 | 2020 |
| Small-molecule inhibitors of SCF-Skp2-Cks1 ubiquitin E3 ligase stabilize nuclear p27kip1 as a novel therapeutic approach to endometrial cancer C Egbuta, J Dubrulle, A Tellechea, MA Manzanares, Y Li, S Duan, ... Cancer Research 78 (13_Supplement), 5231-5231, 2018 | 1 | 2018 |
| Bicyclic inhibitors of PAD4 R Devraj, G Kumaravel, MF Parker, E Beaumont, L Bowles, S Bromidge, ... US Patent 9,963,448, 2018 | 1 | 2018 |
| Steroidal mineralocorticoid receptor antagonists: synthesis and biology C Yarnold, JM Bainbridge, HS Boehm, M Brewer, S Courtney, H Deboves, ... ChemistrySelect 2 (1), 175-189, 2017 | 1 | 2017 |
| Heteroaryl inhibitors of PAD4 R Devraj, G Kumaravel, H Atton, E Beaumont, E Gadouleau, L Gleave, ... US Patent 11,897,866, 2024 | | 2024 |
| Bcl6 inhibitors BR Bellenie, KMJ Cheung, OA Davis, S Hoelder, R Huckvale, G Collie, ... US Patent App. 17/968,159, 2023 | | 2023 |
Antonio MacchiaruloFull Professor, University of PerugiaVerified email at chimfarm.unipg.it
