Identification of essential genes for cancer immunotherapy SJ Patel, NE Sanjana, RJ Kishton, A Eidizadeh, SK Vodnala, M Cam, ... Nature 548 (7669), 537-542, 2017 | 846 | 2017 |
Ionic immune suppression within the tumour microenvironment limits T cell effector function R Eil, SK Vodnala, D Clever, CA Klebanoff, M Sukumar, JH Pan, ... Nature 537 (7621), 539-543, 2016 | 585 | 2016 |
T cell stemness and dysfunction in tumors are triggered by a common mechanism SK Vodnala, R Eil, RJ Kishton, M Sukumar, TN Yamamoto, NH Ha, ... Science 363 (6434), eaau0135, 2019 | 450 | 2019 |
Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence L Vera-Ramirez, SK Vodnala, R Nini, KW Hunter, JE Green Nature communications 9 (1), 1944, 2018 | 384 | 2018 |
Inhibition of AKT signaling uncouples T cell differentiation from expansion for receptor-engineered adoptive immunotherapy CA Klebanoff, JG Crompton, AJ Leonardi, TN Yamamoto, SS Chandran, ... JCI insight 2 (23), 2017 | 198 | 2017 |
T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy TN Yamamoto, PH Lee, SK Vodnala, D Gurusamy, RJ Kishton, Z Yu, ... The Journal of clinical investigation 129 (4), 1551-1565, 2019 | 148 | 2019 |
Multi-phenotype CRISPR-Cas9 screen identifies p38 kinase as a target for adoptive immunotherapies D Gurusamy, AN Henning, TN Yamamoto, Z Yu, N Zacharakis, S Krishna, ... Cancer cell 37 (6), 818-833. e9, 2020 | 132 | 2020 |
Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy E Pérez-Guijarro, HH Yang, RE Araya, R El Meskini, HT Michael, ... Nature medicine 26 (5), 781-791, 2020 | 100 | 2020 |
Bioluminescent Imaging of Trypanosoma brucei Shows Preferential Testis Dissemination Which May Hamper Drug Efficacy in Sleeping Sickness F Claes, SK Vodnala, N van Reet, N Boucher, H Lunden-Miguel, T Baltz, ... PLoS neglected tropical diseases 3 (7), e486, 2009 | 94 | 2009 |
Nitric oxide protects against infection-induced neuroinflammation by preserving the stability of the blood-brain barrier GC Olivera, X Ren, SK Vodnala, J Lu, L Coppo, C Leepiyasakulchai, ... PLoS pathogens 12 (2), e1005442, 2016 | 65 | 2016 |
Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells PH Lee, TN Yamamoto, D Gurusamy, M Sukumar, Z Yu, J Hu-Li, ... Journal of Experimental Medicine 216 (11), 2619-2634, 2019 | 64 | 2019 |
Ebsulfur is a benzisothiazolone cytocidal inhibitor targeting the trypanothione reductase of Trypanosoma brucei J Lu, SK Vodnala, AL Gustavsson, TN Gustafsson, B Sjöberg, ... Journal of Biological Chemistry 288 (38), 27456-27468, 2013 | 64 | 2013 |
Structure–activity relationships of synthetic cordycepin analogues as experimental therapeutics for African trypanosomiasis SK Vodnala, T Lundbäck, E Yeheskieli, B Sjöberg, AL Gustavsson, ... Journal of medicinal chemistry 56 (24), 9861-9873, 2013 | 61 | 2013 |
Distinct toll-like receptor signals regulate cerebral parasite load and interferon α/β and tumor necrosis factor α–dependent T-cell infiltration in the brains of Trypanosoma … DN Amin, SK Vodnala, W Masocha, B Sun, K Kristensson, ME Rottenberg Journal of Infectious Diseases 205 (2), 320-332, 2012 | 61 | 2012 |
Preclinical assessment of the treatment of second-stage African trypanosomiasis with cordycepin and deoxycoformycin SK Vodnala, M Ferella, H Lundén-Miguel, E Betha, N van Reet, DN Amin, ... PLoS neglected tropical diseases 3 (8), e495, 2009 | 60 | 2009 |
Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade DC Palmer, BR Webber, Y Patel, MJ Johnson, CM Kariya, WS Lahr, ... Med 3 (10), 682-704. e8, 2022 | 54 | 2022 |
miR-130a and miR-145 reprogram Gr-1+CD11b+ myeloid cells and inhibit tumor metastasis through improved host immunity H Ishii, SK Vodnala, BR Achyut, JY So, MC Hollander, TF Greten, A Lal, ... Nature communications 9 (1), 2611, 2018 | 36 | 2018 |
Opposing Contributions of Polynucleotide Phosphorylase and the Membrane Protein NlpI to Biofilm Formation by Salmonella enterica Serovar Typhimurium SF Rouf, I Ahmad, N Anwar, SK Vodnala, A Kader, U Römling, M Rhen Journal of bacteriology 193 (2), 580-582, 2011 | 25 | 2011 |
Next generation immunotherapy: enhancing stemness of polyclonal T cells to improve anti-tumor activity RJ Kishton, SK Vodnala, R Vizcardo, NP Restifo Current Opinion in Immunology 74, 39-45, 2022 | 21 | 2022 |
Aicardi-Goutières syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer SK Deasy, R Uehara, SK Vodnala, HH Yang, RA Dass, Y Hu, MP Lee, ... PLoS Genetics 15 (5), e1008020, 2019 | 15 | 2019 |