|Synthesis and function of 3-phosphorylated inositol lipids|
B Vanhaesebroeck, SJ Leevers, K Ahmadi, J Timms, R Katso, PC Driscoll, ...
Annual review of biochemistry 70 (1), 535-602, 2001
|Cellular function of phosphoinositide 3-kinases: implications for development, immunity, homeostasis, and cancer|
R Katso, K Okkenhaug, K Ahmadi, S White, J Timms, MD Waterfield
Annual review of cell and developmental biology 17 (1), 615-675, 2001
|Exploring the specificity of the PI3K family inhibitor LY294002|
SI Gharbi, MJ Zvelebil, SJ Shuttleworth, T Hancox, N Saghir, JF Timms, ...
Biochemical Journal 404 (1), 15-21, 2007
|Evaluation of two-dimensional differential gel electrophoresis for proteomic expression analysis of a model breast cancer cell system|
S Gharbi, P Gaffney, A Yang, MJ Zvelebil, R Cramer, MD Waterfield, ...
Molecular & Cellular Proteomics 1 (2), 91-98, 2002
|Regulation of early events in integrin signaling by protein tyrosine phosphatase SHP-2|
ES Oh, H Gu, TM Saxton, JF Timms, S Hausdorff, EU Frevert, BB Kahn, ...
Molecular and cellular biology 19 (4), 3205-3215, 1999
|Difference gel electrophoresis|
JF Timms, R Cramer
Proteomics 8 (23‐24), 4886-4897, 2008
|Identification of major binding proteins and substrates for the SH2-containing protein tyrosine phosphatase SHP-1 in macrophages|
JF Timms, K Carlberg, H Gu, H Chen, S Kamatkar, MJS Nadler, ...
Molecular and cellular biology 18 (7), 3838-3850, 1998
|Preanalytic influence of sample handling on SELDI-TOF serum protein profiles|
JF Timms, E Arslan-Low, A Gentry-Maharaj, Z Luo, D T’Jampens, ...
Clinical chemistry 53 (4), 645-656, 2007
|The B-cell transmembrane protein CD72 binds to and is an in vivo substrate of the protein tyrosine phosphatase SHP-1|
Y Wu, MJS Nadler, LA Brennan, GD Gish, JF Timms, N Fusaki, ...
Current biology 8 (18), 1009-1017, 1998
|Proteomic analysis of redox‐and ErbB2‐dependent changes in mammary luminal epithelial cells using cysteine‐and lysine‐labelling two‐dimensional difference gel electrophoresis|
HL Chan, S Gharbi, PR Gaffney, R Cramer, MD Waterfield, JF Timms
Proteomics 5 (11), 2908-2926, 2005
|AGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and D|
L Dumartin, HJ Whiteman, ME Weeks, D Hariharan, B Dmitrovic, ...
Cancer research 71 (22), 7091-7102, 2011
|Heat shock protein 27 is the major differentially phosphorylated protein involved in renal epithelial cellular stress response and controls focal adhesion organization and …|
M de Graauw, I Tijdens, R Cramer, S Corless, JF Timms, B Van De Water
Journal of Biological Chemistry 280 (33), 29885-29898, 2005
|SHPS-1 is a scaffold for assembling distinct adhesion-regulated multi-protein complexes in macrophages|
JF Timms, KD Swanson, A Marie-Cardine, M Raab, CE Rudd, B Schraven, ...
Current biology 9 (16), 927-S4, 1999
|The role of S100P in the invasion of pancreatic cancer cells is mediated through cytoskeletal changes and regulation of cathepsin D|
HJ Whiteman, ME Weeks, SE Dowen, S Barry, JF Timms, NR Lemoine, ...
Cancer research 67 (18), 8633-8642, 2007
|Serum CA19-9 is significantly upregulated up to 2 years before diagnosis with pancreatic cancer: implications for early disease detection|
DP O'Brien, NS Sandanayake, C Jenkinson, A Gentry-Maharaj, ...
Clinical Cancer Research 21 (3), 622-631, 2015
|Proteomics study of oxidative stress and Src kinase inhibition in H9C2 cardiomyocytes: a cell model of heart ischemia–reperfusion injury and treatment|
HC Chou, YW Chen, TR Lee, FS Wu, HT Chan, PC Lyu, JF Timms, ...
Free Radical Biology and Medicine 49 (1), 96-108, 2010
|Effects of ErbB-2 overexpression on mitogenic signalling and cell cycle progression in human breast luminal epithelial cells|
JF Timms, SL White, MJ O'Hare, MD Waterfield
Oncogene 21 (43), 6573-6586, 2002
|Serum peptide profiling using MALDI mass spectrometry: Avoiding the pitfalls of coated magnetic beads using well‐established ZipTip technology|
A Tiss, C Smith, S Camuzeaux, M Kabir, S Gayther, U Menon, ...
Proteomics 7 (S1), 77-89, 2007
|Lectin microarray profiling of metastatic breast cancers|
SA Fry, B Afrough, HJ Lomax-Browne, JF Timms, LS Velentzis, ...
Glycobiology 21 (8), 1060-1070, 2011
|Three‐dimensional in vitro cell biology models of ovarian and endometrial cancer|
B Grun, E Benjamin, J Sinclair, JF Timms, IJ Jacobs, SA Gayther, D Dafou
Cell proliferation 42 (2), 219-228, 2009