John F. Timms
TitleCited byYear
Synthesis and function of 3-phosphorylated inositol lipids
B Vanhaesebroeck, SJ Leevers, K Ahmadi, J Timms, R Katso, PC Driscoll, ...
Annual review of biochemistry 70 (1), 535-602, 2001
Cellular function of phosphoinositide 3-kinases: implications for development, immunity, homeostasis, and cancer
R Katso, K Okkenhaug, K Ahmadi, S White, J Timms, MD Waterfield
Annual review of cell and developmental biology 17 (1), 615-675, 2001
Exploring the specificity of the PI3K family inhibitor LY294002
SI Gharbi, MJ Zvelebil, SJ Shuttleworth, T Hancox, N Saghir, JF Timms, ...
Biochemical Journal 404 (1), 15-21, 2007
Evaluation of two-dimensional differential gel electrophoresis for proteomic expression analysis of a model breast cancer cell system
S Gharbi, P Gaffney, A Yang, MJ Zvelebil, R Cramer, MD Waterfield, ...
Molecular & Cellular Proteomics 1 (2), 91-98, 2002
Regulation of early events in integrin signaling by protein tyrosine phosphatase SHP-2
ES Oh, H Gu, TM Saxton, JF Timms, S Hausdorff, EU Frevert, BB Kahn, ...
Molecular and cellular biology 19 (4), 3205-3215, 1999
Difference gel electrophoresis
JF Timms, R Cramer
Proteomics 8 (23‐24), 4886-4897, 2008
Identification of major binding proteins and substrates for the SH2-containing protein tyrosine phosphatase SHP-1 in macrophages
JF Timms, K Carlberg, H Gu, H Chen, S Kamatkar, MJS Nadler, ...
Molecular and cellular biology 18 (7), 3838-3850, 1998
Preanalytic influence of sample handling on SELDI-TOF serum protein profiles
JF Timms, E Arslan-Low, A Gentry-Maharaj, Z Luo, D T’Jampens, ...
Clinical chemistry 53 (4), 645-656, 2007
The B-cell transmembrane protein CD72 binds to and is an in vivo substrate of the protein tyrosine phosphatase SHP-1
Y Wu, MJS Nadler, LA Brennan, GD Gish, JF Timms, N Fusaki, ...
Current biology 8 (18), 1009-1017, 1998
Proteomic analysis of redox‐and ErbB2‐dependent changes in mammary luminal epithelial cells using cysteine‐and lysine‐labelling two‐dimensional difference gel electrophoresis
HL Chan, S Gharbi, PR Gaffney, R Cramer, MD Waterfield, JF Timms
Proteomics 5 (11), 2908-2926, 2005
AGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and D
L Dumartin, HJ Whiteman, ME Weeks, D Hariharan, B Dmitrovic, ...
Cancer research 71 (22), 7091-7102, 2011
Heat shock protein 27 is the major differentially phosphorylated protein involved in renal epithelial cellular stress response and controls focal adhesion organization and …
M de Graauw, I Tijdens, R Cramer, S Corless, JF Timms, B Van De Water
Journal of Biological Chemistry 280 (33), 29885-29898, 2005
SHPS-1 is a scaffold for assembling distinct adhesion-regulated multi-protein complexes in macrophages
JF Timms, KD Swanson, A Marie-Cardine, M Raab, CE Rudd, B Schraven, ...
Current biology 9 (16), 927-S4, 1999
The role of S100P in the invasion of pancreatic cancer cells is mediated through cytoskeletal changes and regulation of cathepsin D
HJ Whiteman, ME Weeks, SE Dowen, S Barry, JF Timms, NR Lemoine, ...
Cancer research 67 (18), 8633-8642, 2007
Serum CA19-9 is significantly upregulated up to 2 years before diagnosis with pancreatic cancer: implications for early disease detection
DP O'Brien, NS Sandanayake, C Jenkinson, A Gentry-Maharaj, ...
Clinical Cancer Research 21 (3), 622-631, 2015
Proteomics study of oxidative stress and Src kinase inhibition in H9C2 cardiomyocytes: a cell model of heart ischemia–reperfusion injury and treatment
HC Chou, YW Chen, TR Lee, FS Wu, HT Chan, PC Lyu, JF Timms, ...
Free Radical Biology and Medicine 49 (1), 96-108, 2010
Effects of ErbB-2 overexpression on mitogenic signalling and cell cycle progression in human breast luminal epithelial cells
JF Timms, SL White, MJ O'Hare, MD Waterfield
Oncogene 21 (43), 6573-6586, 2002
Serum peptide profiling using MALDI mass spectrometry: Avoiding the pitfalls of coated magnetic beads using well‐established ZipTip technology
A Tiss, C Smith, S Camuzeaux, M Kabir, S Gayther, U Menon, ...
Proteomics 7 (S1), 77-89, 2007
Lectin microarray profiling of metastatic breast cancers
SA Fry, B Afrough, HJ Lomax-Browne, JF Timms, LS Velentzis, ...
Glycobiology 21 (8), 1060-1070, 2011
Three‐dimensional in vitro cell biology models of ovarian and endometrial cancer
B Grun, E Benjamin, J Sinclair, JF Timms, IJ Jacobs, SA Gayther, D Dafou
Cell proliferation 42 (2), 219-228, 2009
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