IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer TA Mace, R Shakya, JR Pitarresi, B Swanson, CW McQuinn, S Loftus, ... Gut 67 (2), 320-332, 2018 | 453 | 2018 |
Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner TA Mace, Z Ameen, A Collins, S Wojcik, M Mair, GS Young, JR Fuchs, ... Cancer research 73 (10), 3007-3018, 2013 | 434 | 2013 |
Nitric oxide production by myeloid-derived suppressor cells plays a role in impairing Fc receptor–mediated natural killer cell function A Stiff, P Trikha, B Mundy-Bosse, E McMichael, TA Mace, B Benner, ... Clinical Cancer Research 24 (8), 1891-1904, 2018 | 193 | 2018 |
Myeloid-derived suppressor cells express Bruton's tyrosine kinase and can be depleted in tumor-bearing hosts by ibrutinib treatment A Stiff, P Trikha, R Wesolowski, K Kendra, V Hsu, S Uppati, E McMichael, ... Cancer research 76 (8), 2125-2136, 2016 | 190 | 2016 |
Randomized phase 2 trial of the oncolytic virus pelareorep (Reolysin) in upfront treatment of metastatic pancreatic adenocarcinoma AM Noonan, MR Farren, SM Geyer, Y Huang, S Tahiri, D Ahn, S Mikhail, ... Molecular Therapy 24 (6), 1150-1158, 2016 | 146 | 2016 |
Lipocalin-2 promotes pancreatic ductal adenocarcinoma by regulating inflammation in the tumor microenvironment SB Gomez-Chou, AK Swidnicka-Siergiejko, N Badi, M Chavez-Tomar, ... Cancer research 77 (10), 2647-2660, 2017 | 128 | 2017 |
Generation of monocyte-derived tumor-associated macrophages using tumor-conditioned media provides a novel method to study tumor-associated macrophages in vitro B Benner, L Scarberry, LP Suarez-Kelly, MC Duggan, AR Campbell, ... Journal for immunotherapy of cancer 7, 1-14, 2019 | 120 | 2019 |
Differentiation of CD8+ T cells into effector cells is enhanced by physiological range hyperthermia TA Mace, L Zhong, C Kilpatrick, E Zynda, CT Lee, M Capitano, ... Journal of leukocyte biology 90 (5), 951-962, 2011 | 111 | 2011 |
Hypoxia induces the overexpression of microRNA-21 in pancreatic cancer cells TA Mace, AL Collins, SE Wojcik, CM Croce, GB Lesinski, M Bloomston Journal of surgical research 184 (2), 855-860, 2013 | 109 | 2013 |
Effector CD8+ T cell IFN-γ production and cytotoxicity are enhanced by mild hyperthermia TA Mace, L Zhong, KM Kokolus, EA Repasky International Journal of Hyperthermia 28 (1), 9-18, 2012 | 108 | 2012 |
Hypoxia-driven immunosuppression: a new reason to use thermal therapy in the treatment of cancer? CT Lee, T Mace, EA Repasky International Journal of Hyperthermia 26 (3), 232-246, 2010 | 104 | 2010 |
Systemic immune activity predicts overall survival in treatment-naive patients with metastatic pancreatic cancer MR Farren, TA Mace, S Geyer, S Mikhail, C Wu, K Ciombor, S Tahiri, ... Clinical cancer research 22 (10), 2565-2574, 2016 | 100 | 2016 |
Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines MA Bill, C Nicholas, TA Mace, JP Etter, C Li, EB Schwartz, JR Fuchs, ... Public Library of Science 7 (8), e40724, 2012 | 99 | 2012 |
A phase I trial of single-agent reolysin in patients with relapsed multiple myeloma DW Sborov, GJ Nuovo, A Stiff, T Mace, GB Lesinski, DM Benson Jr, ... Clinical cancer research 20 (23), 5946-5955, 2014 | 89 | 2014 |
Consumption of soy isoflavone enriched bread in men with prostate cancer is associated with reduced proinflammatory cytokines and immunosuppressive cells GB Lesinski, PK Reville, TA Mace, GS Young, J Ahn-Jarvis, ... Cancer Prevention Research 8 (11), 1036-1044, 2015 | 88 | 2015 |
Elevation in body temperature to fever range enhances and prolongs subsequent responsiveness of macrophages to endotoxin challenge CT Lee, L Zhong, TA Mace, EA Repasky PLoS One 7 (1), e30077, 2012 | 83 | 2012 |
Inhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo HM Komar, G Serpa, C Kerscher, E Schwoegl, TA Mace, M Jin, MC Yang, ... Scientific reports 7 (1), 1787, 2017 | 77 | 2017 |
Pancreatic cancer-associated stellate cells: A viable target for reducing immunosuppression in the tumor microenvironment TA Mace, M Bloomston, GB Lesinski Oncoimmunology 2 (7), e24891, 2013 | 71 | 2013 |
Circulating myeloid-derived suppressor cells increase in patients undergoing neo-adjuvant chemotherapy for breast cancer R Wesolowski, MC Duggan, A Stiff, J Markowitz, P Trikha, KM Levine, ... Cancer Immunology, Immunotherapy 66, 1437-1447, 2017 | 70 | 2017 |
CD200 promotes immunosuppression in the pancreatic tumor microenvironment F Choueiry, M Torok, R Shakya, K Agrawal, A Deems, B Benner, A Hinton, ... Journal for immunotherapy of cancer 8 (1), 2020 | 68 | 2020 |