Kate L White
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A new DREADD facilitates the multiplexed chemogenetic interrogation of behavior
E Vardy, JE Robinson, C Li, RHJ Olsen, JF DiBerto, PM Giguere, ...
Neuron 86 (4), 936-946, 2015
Structural basis for selectivity and diversity in angiotensin II receptors
H Zhang, GW Han, A Batyuk, A Ishchenko, KL White, N Patel, ...
Nature 544 (7650), 327-332, 2017
Allosteric coupling of drug binding and intracellular signaling in the A2A adenosine receptor
MT Eddy, MY Lee, ZG Gao, KL White, T Didenko, R Horst, M Audet, ...
Cell 172 (1), 68-80. e12, 2018
The G protein–biased κ-opioid receptor agonist RB-64 is analgesic with a unique spectrum of activities in vivo
KL White, JE Robinson, H Zhu, JF DiBerto, PR Polepally, JK Zjawiony, ...
Journal of Pharmacology and Experimental Therapeutics 352 (1), 98-109, 2015
Structural connection between activation microswitch and allosteric sodium site in GPCR signaling
KL White, MT Eddy, ZG Gao, GW Han, T Lian, A Deary, N Patel, ...
Structure 26 (2), 259-269. e5, 2018
Identification of novel functionally selective κ-opioid receptor scaffolds
KL White, AP Scopton, ML Rives, RV Bikbulatov, PR Polepally, PJ Brown, ...
Molecular pharmacology 85 (1), 83-90, 2014
Single-molecule view of basal activity and activation mechanisms of the G protein-coupled receptor β2AR
R Lamichhane, JJ Liu, G Pljevaljcic, KL White, E van der Schans, ...
Proceedings of the National Academy of Sciences 112 (46), 14254-14259, 2015
NMR structure and dynamics of the agonist dynorphin peptide bound to the human kappa opioid receptor
C O’Connor, KL White, N Doncescu, T Didenko, BL Roth, G Czaplicki, ...
Proceedings of the National Academy of Sciences 112 (38), 11852-11857, 2015
Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists
T Claff, J Yu, V Blais, N Patel, C Martin, L Wu, GW Han, BJ Holleran, ...
Science advances 5 (11), eaax9115, 2019
Opportunities and challenges in building a spatiotemporal multi-scale model of the human pancreatic β cell
J Singla, KM McClary, KL White, F Alber, A Sali, RC Stevens
Cell 173 (1), 11-19, 2018
Federating structural models and data: outcomes from a workshop on archiving integrative structures
HM Berman, PD Adams, AA Bonvin, SK Burley, B Carragher, W Chiu, ...
Structure 27 (12), 1745-1759, 2019
Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor
M Audet, KL White, B Breton, B Zarzycka, GW Han, Y Lu, C Gati, A Batyuk, ...
Nature chemical biology 15 (1), 11-17, 2019
Biased signaling of the G-protein-coupled receptor β2AR is governed by conformational exchange kinetics
R Lamichhane, JJ Liu, KL White, V Katritch, RC Stevens, K WŁthrich, ...
Structure 28 (3), 371-377. e3, 2020
Receptor reserve moderates mesolimbic responses to opioids in a humanized mouse model of the OPRM1 A118G polymorphism
JE Robinson, E Vardy, JF DiBerto, VI Chefer, KL White, EW Fish, M Chen, ...
Neuropsychopharmacology 40 (11), 2614-2622, 2015
In Vitro and In Vivo Characterization of the Alkaloid Nuciferine
MS Farrell, JD McCorvy, XP Huang, DJ Urban, KL White, PM Giguere, ...
PLoS One 11 (3), e0150602, 2016
Visualizing subcellular rearrangements in intact β cells using soft x-ray tomography
KL White, J Singla, V Loconte, JH Chen, A Ekman, L Sun, X Zhang, ...
Science advances 6 (50), eabc8262, 2020
Visualizing insulin vesicle neighborhoods in β cells by cryo–electron tomography
X Zhang, SD Carter, J Singla, KL White, PC Butler, RC Stevens, ...
Science Advances 6 (50), eabc8258, 2020
Kappa-opioid receptor-selective dicarboxylic ester-derived salvinorin A ligands
PR Polepally, K White, E Vardy, BL Roth, D Ferreira, JK Zjawiony
Bioorganic & medicinal chemistry letters 23 (10), 2860-2862, 2013
Psychotomimetic effects of kappa opioid receptor agonists
KL White, BL Roth
Biological psychiatry 72 (10), 797-798, 2012
Bayesian metamodeling of complex biological systems across varying representations
B Raveh, L Sun, KL White, T Sanyal, J Tempkin, D Zheng, K Bharath, ...
Proceedings of the National Academy of Sciences 118 (35), e2104559118, 2021
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