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Daniel De Carvalho
Daniel De Carvalho
Professor, University of Toronto. Senior Scientist, Princess Margaret Cancer Centre
Zweryfikowany adres z uhnresearch.ca - Strona główna
Tytuł
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Cytowane przez
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DNA-demethylating agents target colorectal cancer cells by inducing viral mimicry by endogenous transcripts
D Roulois, HL Yau, R Singhania, Y Wang, A Danesh, SY Shen, H Han, ...
Cell 162 (5), 961-973, 2015
12702015
Gene body methylation can alter gene expression and is a therapeutic target in cancer
X Yang, H Han, DD De Carvalho, FD Lay, PA Jones, G Liang
Cancer cell 26 (4), 577-590, 2014
11422014
Epigenetic modifications as therapeutic targets
TK Kelly, DD De Carvalho, PA Jones
Nature biotechnology 28 (10), 1069-1078, 2010
8872010
Sensitive tumour detection and classification using plasma cell-free DNA methylomes
SY Shen, R Singhania, G Fehringer, A Chakravarthy, MHA Roehrl, ...
Nature 563 (7732), 579-583, 2018
7102018
LSD1 ablation stimulates anti-tumor immunity and enables checkpoint blockade
W Sheng, MW LaFleur, TH Nguyen, S Chen, A Chakravarthy, JR Conway, ...
Cell 174 (3), 549-563. e19, 2018
5522018
TGF-β-associated extracellular matrix genes link cancer-associated fibroblasts to immune evasion and immunotherapy failure
A Chakravarthy, L Khan, NP Bensler, P Bose, DD De Carvalho
Nature communications 9 (1), 4692, 2018
4592018
Epigenetic therapy in immune-oncology
PA Jones, H Ohtani, A Chakravarthy, DD De Carvalho
Nature Reviews Cancer 19 (3), 151-161, 2019
4182019
DNA methylation screening identifies driver epigenetic events of cancer cell survival
DD De Carvalho, S Sharma, JS You, SF Su, PC Taberlay, TK Kelly, ...
Cancer cell 21 (5), 655-667, 2012
3282012
DNA methylation and cellular reprogramming
DD De Carvalho, JS You, PA Jones
Trends in cell biology 20 (10), 609-617, 2010
2672010
Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression
S Chen, G Zhu, Y Yang, F Wang, YT Xiao, N Zhang, X Bian, Y Zhu, Y Yu, ...
Nature cell biology 23 (1), 87-98, 2021
2412021
A clinically applicable integrative molecular classification of meningiomas
F Nassiri, J Liu, V Patil, Y Mamatjan, JZ Wang, R Hugh-White, AM Macklin, ...
Nature 597 (7874), 119-125, 2021
2312021
Integrated (epi)-genomic analyses identify subgroup-specific therapeutic targets in CNS rhabdoid tumors
J Torchia, B Golbourn, S Feng, KC Ho, P Sin-Chan, A Vasiljevic, ...
Cancer cell 30 (6), 891-908, 2016
2252016
Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes
PV Nuzzo, JE Berchuck, K Korthauer, S Spisak, AH Nassar, S Abou Alaiwi, ...
Nature medicine 26 (7), 1041-1043, 2020
2132020
Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes
F Nassiri, A Chakravarthy, S Feng, SY Shen, R Nejad, JA Zuccato, ...
Nature medicine 26 (7), 1044-1047, 2020
2102020
Mutant IDH1 downregulates ATM and alters DNA repair and sensitivity to DNA damage independent of TET2
S Inoue, WY Li, A Tseng, I Beerman, AJ Elia, SC Bendall, F Lemonnier, ...
Cancer cell 30 (2), 337-348, 2016
2082016
Polycomb-repressed genes have permissive enhancers that initiate reprogramming
PC Taberlay, TK Kelly, CC Liu, JS You, DD De Carvalho, TB Miranda, ...
Cell 147 (6), 1283-1294, 2011
2002011
IL17 promotes mammary tumor progression by changing the behavior of tumor cells and eliciting tumorigenic neutrophils recruitment
L Benevides, DM da Fonseca, PB Donate, DG Tiezzi, DD De Carvalho, ...
Cancer research 75 (18), 3788-3799, 2015
1982015
Pervasive H3K27 acetylation leads to ERV expression and a therapeutic vulnerability in H3K27M gliomas
B Krug, N De Jay, AS Harutyunyan, S Deshmukh, DM Marchione, ...
Cancer cell 35 (5), 782-797. e8, 2019
1762019
Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency
P Mehdipour, SA Marhon, I Ettayebi, A Chakravarthy, A Hosseini, Y Wang, ...
Nature 588 (7836), 169-173, 2020
1742020
OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes
JS You, TK Kelly, DD De Carvalho, PC Taberlay, G Liang, PA Jones
Proceedings of the National Academy of Sciences 108 (35), 14497-14502, 2011
1622011
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