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Adam E. Mullick
Adam E. Mullick
Ionis Pharmaceuticals, Inc.
Zweryfikowany adres z ionisph.com - Strona główna
Tytuł
Cytowane przez
Cytowane przez
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CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation
FJ Sheedy, A Grebe, KJ Rayner, P Kalantari, B Ramkhelawon, ...
Nature immunology 14 (8), 812-820, 2013
9602013
Modulation of atherosclerosis in mice by Toll-like receptor 2
AE Mullick, PS Tobias, LK Curtiss
The Journal of clinical investigation 115 (11), 3149-3156, 2005
6732005
Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans
MJ Graham, RG Lee, TA Bell III, W Fu, AE Mullick, VJ Alexander, ...
Circulation research 112 (11), 1479-1490, 2013
4192013
Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events
AE Mullick, K Soldau, WB Kiosses, TA Bell III, PS Tobias, LK Curtiss
The Journal of experimental medicine 205 (2), 373-383, 2008
2822008
ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors
PLSM Gordts, R Nock, NH Son, B Ramms, I Lew, JC Gonzales, ...
The Journal of clinical investigation 126 (8), 2855-2866, 2016
2422016
Endothelial cell CD36 optimizes tissue fatty acid uptake
NH Son, D Basu, D Samovski, TA Pietka, VS Peche, F Willecke, X Fang, ...
The Journal of clinical investigation 128 (10), 4329-4342, 2018
2032018
Antisense oligonucleotide directed to human apolipoprotein B-100 reduces lipoprotein (a) levels and oxidized phospholipids on human apolipoprotein B-100 particles in …
E Merki, MJ Graham, AE Mullick, ER Miller, RM Crooke, RE Pitas, ...
Circulation 118 (7), 743-753, 2008
186*2008
Antisense oligonucleotide lowers plasma levels of apolipoprotein (a) and lipoprotein (a) in transgenic mice
E Merki, M Graham, A Taleb, G Leibundgut, X Yang, ER Miller, W Fu, ...
Journal of the American College of Cardiology 57 (15), 1611-1621, 2011
1442011
Mechanism of increased LDL (low-density lipoprotein) and decreased triglycerides with SGLT2 (sodium-glucose cotransporter 2) inhibition
D Basu, LA Huggins, D Scerbo, J Obunike, AE Mullick, PL Rothenberg, ...
Arteriosclerosis, thrombosis, and vascular biology 38 (9), 2207-2216, 2018
1382018
Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle
TP Prakash, AE Mullick, RG Lee, J Yu, ST Yeh, A Low, AE Chappell, ...
Nucleic Acids Research 47 (12), 6029-6044, 2019
1302019
Renin angiotensin aldosterone inhibition in the treatment of cardiovascular disease
CM Ferrario, AE Mullick
Pharmacological research 125, 57-71, 2017
1262017
Direct visualization of lipid deposition and reverse lipid transport in a perfused artery: roles of VLDL and HDL
JC Rutledge, AE Mullick, G Gardner, IJ Goldberg
Circulation research 86 (7), 768-773, 2000
1162000
Modulation of apolipoprotein CIII (ApoCIII) expression
A Mullick, RM Crooke, MJ Graham, KW Dobie, R Lee
US Patent 9,157,082, 2015
1072015
Hypercholesterolemia induced by a PCSK9 gain-of-function mutation augments angiotensin ii–induced abdominal aortic aneurysms in C57BL/6 mice—brief report
H Lu, DA Howatt, A Balakrishnan, MJ Graham, AE Mullick, A Daugherty
Arteriosclerosis, thrombosis, and vascular biology 36 (9), 1753-1757, 2016
1022016
Conjugation of hydrophobic moieties enhances potency of antisense oligonucleotides in the muscle of rodents and non-human primates
ME Østergaard, M Jackson, A Low, A E. Chappell, R G. Lee, RQ Peralta, ...
Nucleic Acids Research 47 (12), 6045-6058, 2019
962019
Hyperhomocysteinemia evoked by folate depletion: effects on coronary and carotid arterial function
JD Symons, AE Mullick, JL Ensunsa, AA Ma, JC Rutledge
Arteriosclerosis, thrombosis, and vascular biology 22 (5), 772-780, 2002
932002
Toll-like receptors and atherosclerosis: key contributors in disease and health?
AE Mullick, PS Tobias, LK Curtiss
Immunologic research 34, 193-209, 2006
892006
Angiotensinogen exerts effects independent of angiotensin II
H Lu, C Wu, DA Howatt, A Balakrishnan, JJ Moorleghen, X Chen, M Zhao, ...
Arteriosclerosis, thrombosis, and vascular biology 36 (2), 256-265, 2016
832016
Glucose lowering by SGLT2-inhibitor empagliflozin accelerates atherosclerosis regression in hyperglycemic STZ-diabetic mice
J Pennig, P Scherrer, MC Gissler, N Anto-Michel, N Hoppe, L Füner, ...
Scientific Reports 9 (1), 17937, 2019
672019
Antagonism of scavenger receptor CD36 by 5A peptide prevents chronic kidney disease progression in mice independent of blood pressure regulation
ACP Souza, AV Bocharov, IN Baranova, TG Vishnyakova, YG Huang, ...
Kidney international 89 (4), 809-822, 2016
672016
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