CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation FJ Sheedy, A Grebe, KJ Rayner, P Kalantari, B Ramkhelawon, ... Nature immunology 14 (8), 812-820, 2013 | 960 | 2013 |
Modulation of atherosclerosis in mice by Toll-like receptor 2 AE Mullick, PS Tobias, LK Curtiss The Journal of clinical investigation 115 (11), 3149-3156, 2005 | 673 | 2005 |
Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans MJ Graham, RG Lee, TA Bell III, W Fu, AE Mullick, VJ Alexander, ... Circulation research 112 (11), 1479-1490, 2013 | 419 | 2013 |
Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events AE Mullick, K Soldau, WB Kiosses, TA Bell III, PS Tobias, LK Curtiss The Journal of experimental medicine 205 (2), 373-383, 2008 | 282 | 2008 |
ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors PLSM Gordts, R Nock, NH Son, B Ramms, I Lew, JC Gonzales, ... The Journal of clinical investigation 126 (8), 2855-2866, 2016 | 242 | 2016 |
Endothelial cell CD36 optimizes tissue fatty acid uptake NH Son, D Basu, D Samovski, TA Pietka, VS Peche, F Willecke, X Fang, ... The Journal of clinical investigation 128 (10), 4329-4342, 2018 | 203 | 2018 |
Antisense oligonucleotide directed to human apolipoprotein B-100 reduces lipoprotein (a) levels and oxidized phospholipids on human apolipoprotein B-100 particles in … E Merki, MJ Graham, AE Mullick, ER Miller, RM Crooke, RE Pitas, ... Circulation 118 (7), 743-753, 2008 | 186* | 2008 |
Antisense oligonucleotide lowers plasma levels of apolipoprotein (a) and lipoprotein (a) in transgenic mice E Merki, M Graham, A Taleb, G Leibundgut, X Yang, ER Miller, W Fu, ... Journal of the American College of Cardiology 57 (15), 1611-1621, 2011 | 144 | 2011 |
Mechanism of increased LDL (low-density lipoprotein) and decreased triglycerides with SGLT2 (sodium-glucose cotransporter 2) inhibition D Basu, LA Huggins, D Scerbo, J Obunike, AE Mullick, PL Rothenberg, ... Arteriosclerosis, thrombosis, and vascular biology 38 (9), 2207-2216, 2018 | 138 | 2018 |
Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle TP Prakash, AE Mullick, RG Lee, J Yu, ST Yeh, A Low, AE Chappell, ... Nucleic Acids Research 47 (12), 6029-6044, 2019 | 130 | 2019 |
Renin angiotensin aldosterone inhibition in the treatment of cardiovascular disease CM Ferrario, AE Mullick Pharmacological research 125, 57-71, 2017 | 126 | 2017 |
Direct visualization of lipid deposition and reverse lipid transport in a perfused artery: roles of VLDL and HDL JC Rutledge, AE Mullick, G Gardner, IJ Goldberg Circulation research 86 (7), 768-773, 2000 | 116 | 2000 |
Modulation of apolipoprotein CIII (ApoCIII) expression A Mullick, RM Crooke, MJ Graham, KW Dobie, R Lee US Patent 9,157,082, 2015 | 107 | 2015 |
Hypercholesterolemia induced by a PCSK9 gain-of-function mutation augments angiotensin ii–induced abdominal aortic aneurysms in C57BL/6 mice—brief report H Lu, DA Howatt, A Balakrishnan, MJ Graham, AE Mullick, A Daugherty Arteriosclerosis, thrombosis, and vascular biology 36 (9), 1753-1757, 2016 | 102 | 2016 |
Conjugation of hydrophobic moieties enhances potency of antisense oligonucleotides in the muscle of rodents and non-human primates ME Østergaard, M Jackson, A Low, A E. Chappell, R G. Lee, RQ Peralta, ... Nucleic Acids Research 47 (12), 6045-6058, 2019 | 96 | 2019 |
Hyperhomocysteinemia evoked by folate depletion: effects on coronary and carotid arterial function JD Symons, AE Mullick, JL Ensunsa, AA Ma, JC Rutledge Arteriosclerosis, thrombosis, and vascular biology 22 (5), 772-780, 2002 | 93 | 2002 |
Toll-like receptors and atherosclerosis: key contributors in disease and health? AE Mullick, PS Tobias, LK Curtiss Immunologic research 34, 193-209, 2006 | 89 | 2006 |
Angiotensinogen exerts effects independent of angiotensin II H Lu, C Wu, DA Howatt, A Balakrishnan, JJ Moorleghen, X Chen, M Zhao, ... Arteriosclerosis, thrombosis, and vascular biology 36 (2), 256-265, 2016 | 83 | 2016 |
Glucose lowering by SGLT2-inhibitor empagliflozin accelerates atherosclerosis regression in hyperglycemic STZ-diabetic mice J Pennig, P Scherrer, MC Gissler, N Anto-Michel, N Hoppe, L Füner, ... Scientific Reports 9 (1), 17937, 2019 | 67 | 2019 |
Antagonism of scavenger receptor CD36 by 5A peptide prevents chronic kidney disease progression in mice independent of blood pressure regulation ACP Souza, AV Bocharov, IN Baranova, TG Vishnyakova, YG Huang, ... Kidney international 89 (4), 809-822, 2016 | 67 | 2016 |