Martin Grininger
Martin Grininger
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Inhibition of the fungal fatty acid synthase type I multienzyme complex
P Johansson, B Wiltschi, P Kumari, B Kessler, C Vonrhein, J Vonck, ...
Proceedings of the National Academy of Sciences 105 (35), 12803-12808, 2008
Parameters affecting the X-ray dose absorbed by macromolecular crystals
JW Murray, E Rudino-Pinera, RL Owen, M Grininger, RBG Ravelli, ...
Journal of synchrotron radiation 12 (3), 268-275, 2005
Engineering fungal de novo fatty acid synthesis for short chain fatty acid production
J Gajewski, R Pavlovic, M Fischer, E Boles, M Grininger
Nature communications 8 (1), 1-8, 2017
Expanding the product portfolio of fungal type I fatty acid synthases
Z Zhu, YJ Zhou, A Krivoruchko, M Grininger, ZK Zhao, J Nielsen
Nature chemical biology 13 (4), 360-362, 2017
Protein denaturation at the air-water interface and how to prevent it
E D'Imprima, D Floris, M Joppe, R Sánchez, M Grininger, W Kühlbrandt
Elife 8, e42747, 2019
Direct structural insight into the substrate-shuttling mechanism of yeast fatty acid synthase by electron cryomicroscopy
P Gipson, DJ Mills, R Wouts, M Grininger, J Vonck, W Kühlbrandt
Proceedings of the National Academy of Sciences 107 (20), 9164-9169, 2010
Engineering strategies for rational polyketide synthase design
M Klaus, M Grininger
Natural product reports 35 (10), 1070-1081, 2018
Dodecins: a family of lumichrome binding proteins
M Grininger, K Zeth, D Oesterhelt
Journal of molecular biology 357 (3), 842-857, 2006
Engineering fatty acid synthases for directed polyketide production
J Gajewski, F Buelens, S Serdjukow, M Janßen, N Cortina, H Grubmüller, ...
Nature chemical biology 13 (4), 363-365, 2017
Dodecin is the key player in flavin homeostasis of archaea
M Grininger, H Staudt, P Johansson, J Wachtveitl, D Oesterhelt
Journal of Biological Chemistry 284 (19), 13068-13076, 2009
Perspectives on the evolution, assembly and conformational dynamics of fatty acid synthase type I (FAS I) systems
M Grininger
Current opinion in structural biology 25, 49-56, 2014
Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase
P Johansson, B Mulinacci, C Koestler, R Vollrath, D Oesterhelt, ...
Structure 17 (8), 1063-1074, 2009
Structural and biochemical characterization of a halophilic archaeal alkaline phosphatase
A Wende, P Johansson, R Vollrath, M Dyall-Smith, D Oesterhelt, ...
Journal of molecular biology 400 (1), 52-62, 2010
Structure and conformational variability of the Mycobacterium tuberculosis fatty acid synthase multienzyme complex
L Ciccarelli, SR Connell, M Enderle, DJ Mills, J Vonck, M Grininger
Structure 21 (7), 1251-1257, 2013
Dodecin sequesters FAD in closed conformation from the aqueous solution
M Grininger, F Seiler, K Zeth, D Oesterhelt
Journal of molecular biology 364 (4), 561-566, 2006
Mechanism of substrate shuttling by the acyl-carrier protein within the fatty acid mega-synthase
C Anselmi, M Grininger, P Gipson, JD Faraldo-Gómez
Journal of the American Chemical Society 132 (35), 12357-12364, 2010
Fatty acid biosynthesis: Chain‐length regulation and control
CS Heil, SS Wehrheim, KS Paithankar, M Grininger
ChemBioChem 20 (18), 2298-2321, 2019
Ultrafast excited-state deactivation of flavins bound to dodecin
H Staudt, D Oesterhelt, M Grininger, J Wachtveitl
Journal of Biological Chemistry 287 (21), 17637-17644, 2012
Cryo‐EM structure of fatty acid synthase (FAS) from Rhodosporidium toruloides provides insights into the evolutionary development of fungal FAS
M Fischer, D Rhinow, Z Zhu, DJ Mills, ZK Zhao, J Vonck, M Grininger
Protein Science 24 (6), 987-995, 2015
Multi-ligand-binding flavoprotein dodecin as a key element for reversible surface modification in nano-biotechnology
C Gutiérrez Sánchez, Q Su, H Schönherr, M Grininger, G Nöll
ACS nano 9 (4), 3491-3500, 2015
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