| IL-11 is a crucial determinant of cardiovascular fibrosis S Schafer, S Viswanathan, AA Widjaja, WW Lim, A Moreno-Moral, ... Nature 552 (7683), 110-115, 2017 | 516 | 2017 |
| Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis B Ng, J Dong, G D’Agostino, S Viswanathan, AA Widjaja, WW Lim, ... Science translational medicine 11 (511), eaaw1237, 2019 | 209 | 2019 |
| Inhibiting interleukin 11 signaling reduces hepatocyte death and liver fibrosis, inflammation, and steatosis in mouse models of nonalcoholic steatohepatitis AA Widjaja, BK Singh, E Adami, S Viswanathan, J Dong, GA D’Agostino, ... Gastroenterology 157 (3), 777-792. e14, 2019 | 205 | 2019 |
| Bipolar electrogram shannon entropy at sites of rotational activation: implications for ablation of atrial fibrillation AN Ganesan, P Kuklik, DH Lau, AG Brooks, M Baumert, WW Lim, ... Circulation: Arrhythmia and Electrophysiology 6 (1), 48-57, 2013 | 151 | 2013 |
| Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH J Dong, S Viswanathan, E Adami, BK Singh, SP Chothani, B Ng, WW Lim, ... Nature communications 12 (1), 66, 2021 | 82 | 2021 |
| Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury AA Widjaja, J Dong, E Adami, S Viswanathan, B Ng, LS Pakkiri, ... Science Translational Medicine 13 (597), eaba8146, 2021 | 56* | 2021 |
| Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models WW Lim, B Corden, B Ng, K Vanezis, G D’Agostino, AA Widjaja, WH Song, ... Scientific reports 10 (1), 17853, 2020 | 50 | 2020 |
| Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice WW Lim, B Ng, A Widjaja, C Xie, L Su, N Ko, SY Lim, XY Kwek, S Lim, ... PLoS One 15 (1), e0227505, 2020 | 49 | 2020 |
| A high-resolution map of human RNA translation SP Chothani, E Adami, AA Widjaja, SR Langley, S Viswanathan, CJ Pua, ... Molecular cell 82 (15), 2885-2899. e8, 2022 | 42 | 2022 |
| IL11 stimulates IL33 expression and proinflammatory fibroblast activation across tissues AA Widjaja, S Chothani, S Viswanathan, JWT Goh, WW Lim, SA Cook International Journal of Molecular Sciences 23 (16), 8900, 2022 | 24 | 2022 |
| Inhibition of IL11 signaling reduces aortic pathology in murine marfan syndrome WW Lim, J Dong, B Ng, AA Widjaja, C Xie, L Su, XY Kwek, NGZ Tee, ... Circulation Research 130 (5), 728-740, 2022 | 24 | 2022 |
| IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR initiating a mesenchymal program in stromal, epithelial, and cancer cells AA Widjaja, S Viswanathan, JGW Ting, J Tan, SG Shekeran, D Carling, ... IScience 25 (8), 2022 | 18 | 2022 |
| IL11 activates pancreatic stellate cells and causes pancreatic inflammation, fibrosis and atrophy in a mouse model of pancreatitis B Ng, S Viswanathan, AA Widjaja, WW Lim, SG Shekeran, JWT Goh, ... International Journal of Molecular Sciences 23 (7), 3549, 2022 | 17 | 2022 |
| Therapeutic targeting of interleukin-11 signalling reduces pressure overload–induced cardiac fibrosis in mice B Corden, WW Lim, W Song, X Chen, NSJ Ko, L Su, NGZ Tee, E Adami, ... Journal of Cardiovascular Translational Research 14, 222-228, 2021 | 17 | 2021 |
| Treatment of SMC mediated disease SA Cook, S Schaefer, WW Lim, BWM Ng US Patent 11,780,898, 2023 | 14 | 2023 |
| Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease AA Widjaja, S Viswanathan, SG Shekeran, E Adami, WW Lim, S Chothani, ... Nature Communications 13 (1), 7497, 2022 | 14 | 2022 |
| Antibody‐mediated neutralization of IL11 signalling reduces ERK activation and cardiac fibrosis in a mouse model of severe pressure overload WW Lim, B Corden, L Ye, S Viswanathan, AA Widjaja, C Xie, L Su, ... Clinical and Experimental Pharmacology and Physiology 48 (4), 605-613, 2021 | 13 | 2021 |
| Electrophysiological and structural remodeling of the atria in a mouse model of troponin-I mutation linked hypertrophic cardiomyopathy: implications for atrial fibrillation WW Lim, M Neo, S Thanigaimani, P Kuklik, AN Ganesan, DH Lau, ... International Journal of Molecular Sciences 22 (13), 6941, 2021 | 10 | 2021 |
| Interleukin-11: A potential biomarker and molecular therapeutic target in non-small cell lung cancer JH Leung, B Ng, WW Lim Cells 11 (14), 2257, 2022 | 8 | 2022 |
| Cardiomyocyte-restricted expression of IL11 causes cardiac fibrosis, inflammation, and dysfunction M Sweeney, K O’Fee, C Villanueva-Hayes, E Rahman, M Lee, K Vanezis, ... International Journal of Molecular Sciences 24 (16), 12989, 2023 | 5 | 2023 |
Anissa WidjajaAssistant Professor, Duke-NUS Medical SchoolVerified email at duke-nus.edu.sg
