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Sarah Piel
Sarah Piel
Post-doctoral Researcher, Universitätsklinikum Düsseldorf
Zweryfikowany adres z med.uni-duesseldorf.de
Tytuł
Cytowane przez
Cytowane przez
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Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency
JK Ehinger, S Piel, R Ford, M Karlsson, F Sjövall, EÅ Frostner, S Morota, ...
Nature communications 7 (1), 12317, 2016
1292016
Metformin induces lactate production in peripheral blood mononuclear cells and platelets through specific mitochondrial complex I inhibition
S Piel, JK Ehinger, E Elmer, MJ Hansson
Acta physiologica 213 (1), 171-180, 2015
762015
White adipose tissue browning in the R6/2 mouse model of Huntington’s disease
AC McCourt, L Jakobsson, S Larsson, C Holm, S Piel, E Elmér, ...
PloS one 11 (8), e0159870, 2016
282016
Bioenergetic bypass using cell-permeable succinate, but not methylene blue, attenuates metformin-induced lactate production
S Piel, JK Ehinger, I Chamkha, EÅ Frostner, F Sjövall, E Elmér, ...
Intensive care medicine experimental 6, 1-12, 2018
242018
Changes in energy metabolism due to acute rotenone-induced mitochondrial complex I dysfunction–An in vivo large animal model
M Karlsson, JK Ehinger, S Piel, F Sjövall, J Henriksnäs, U Höglund, ...
Mitochondrion 31, 56-62, 2016
212016
α1-Microglobulin (A1M) Protects Human Proximal Tubule Epithelial Cells from Heme-Induced Damage In Vitro
A Kristiansson, S Davidsson, ME Johansson, S Piel, E Elmér, ...
International journal of molecular sciences 21 (16), 5825, 2020
192020
Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose
S Piel, I Chamkha, AK Dehlin, JK Ehinger, F Sjövall, E Elmér, MJ Hansson
PLoS One 15 (4), e0231173, 2020
172020
Mitochondrial respiratory chain complex I dysfunction induced by N-methyl carbamate ex vivo can be alleviated with a cell-permeable succinate prodrug
JI Janowska, S Piel, N Saliba, CD Kim, DH Jang, M Karlsson, TJ Kilbaugh, ...
Toxicology in Vitro 65, 104794, 2020
152020
In vitro comparison of hydroxocobalamin (B12a) and the mitochondrial directed therapy by a succinate prodrug in a cellular model of cyanide poisoning
S Owiredu, A Ranganathan, JC Greenwood, S Piel, JI Janowska, ...
Toxicology Reports 7, 1263-1271, 2020
132020
Respiratory uncoupling by increased H+ or K+ flux is beneficial for heart mitochondrial turnover of reactive oxygen species but not for permeability transition
S Morota, S Piel, MJ Hansson
BMC cell biology 14, 1-10, 2013
112013
Alterations in cerebral and cardiac mitochondrial function in a porcine model of acute carbon monoxide poisoning
DH Jang, S Piel, JC Greenwood, M Kelly, VM Mazandi, A Ranganathan, ...
Clinical Toxicology 59 (9), 801-809, 2021
92021
Mitochondrial Physiology
E Gnaiger
The many Faces 158, 2005
7*2005
Emerging cellular-based therapies in carbon monoxide poisoning
DH Jang, S Piel, JC Greenwood, JK Ehinger, TJ Kilbaugh
American Journal of Physiology-Cell Physiology 321 (2), C269-C275, 2021
52021
Preliminary Research: Application of Non-Invasive Measure of Cytochrome c Oxidase Redox States and Mitochondrial Function in a Porcine Model of Carbon …
A Lewis, RM Forti, O Alomaja, C Mesaros, S Piel, JC Greenwood, ...
Journal of Medical Toxicology 18 (3), 214-222, 2022
42022
Alteration in cerebral metabolism in a rodent model of acute sub-lethal cyanide poisoning
O Alomaja, FS Shofer, JC Greenwood, S Piel, C Clayman, C Mesaros, ...
Journal of Medical Toxicology 19 (2), 196-204, 2023
22023
Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning
S Piel, JI Janowska, JL Ward, MJ McManus, JS Jose, J Starr, M Sheldon, ...
Scientific Reports 12 (1), 20329, 2022
22022
Succinate prodrugs for use in the treatment of lactic acidosis or drug-induced side-effects due to Complex I-related impairment of mitochondrial oxidative phosphorylation
E Elmer, MJ Hansson, KHJ Ehinger, S Piel, S Moss
US Patent 10,307,389, 2019
22019
Mitochondrial targeted biofuels as countermeasures against chemical threats
S Piel, J Janowska, JK Ehinger, M Karlsson, TJ Kilbaugh
A44. CRITICAL CARE: ONE THOUSAND AND ONE NIGHTS-NON-PULMONARY CRITICAL CARE …, 2019
22019
Mitochondrial medicine. New strategies to evaluate drug toxicity and develop pharmacological protection of the cell’s powerhouse.
S Piel
12018
NVP019 POTENTLY INHIBITS CYCLOPHILIN D-DEPENDENT MITOCHONDRIAL PERMEABILITY TRANSITION IN HUMAN HEART AND REDUCES MYOCARDIAL INFARCT SIZE IN MICE
B Pillot, S Piel, F Derimay, A Gharib, MJ Hansson, M Ovize
Journal of the American College of Cardiology 65 (10S), A159-A159, 2015
12015
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