Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency JK Ehinger, S Piel, R Ford, M Karlsson, F Sjövall, EÅ Frostner, S Morota, ... Nature communications 7 (1), 12317, 2016 | 129 | 2016 |
Metformin induces lactate production in peripheral blood mononuclear cells and platelets through specific mitochondrial complex I inhibition S Piel, JK Ehinger, E Elmer, MJ Hansson Acta physiologica 213 (1), 171-180, 2015 | 76 | 2015 |
White adipose tissue browning in the R6/2 mouse model of Huntington’s disease AC McCourt, L Jakobsson, S Larsson, C Holm, S Piel, E Elmér, ... PloS one 11 (8), e0159870, 2016 | 28 | 2016 |
Bioenergetic bypass using cell-permeable succinate, but not methylene blue, attenuates metformin-induced lactate production S Piel, JK Ehinger, I Chamkha, EÅ Frostner, F Sjövall, E Elmér, ... Intensive care medicine experimental 6, 1-12, 2018 | 24 | 2018 |
Changes in energy metabolism due to acute rotenone-induced mitochondrial complex I dysfunction–An in vivo large animal model M Karlsson, JK Ehinger, S Piel, F Sjövall, J Henriksnäs, U Höglund, ... Mitochondrion 31, 56-62, 2016 | 21 | 2016 |
α1-Microglobulin (A1M) Protects Human Proximal Tubule Epithelial Cells from Heme-Induced Damage In Vitro A Kristiansson, S Davidsson, ME Johansson, S Piel, E Elmér, ... International journal of molecular sciences 21 (16), 5825, 2020 | 19 | 2020 |
Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose S Piel, I Chamkha, AK Dehlin, JK Ehinger, F Sjövall, E Elmér, MJ Hansson PLoS One 15 (4), e0231173, 2020 | 17 | 2020 |
Mitochondrial respiratory chain complex I dysfunction induced by N-methyl carbamate ex vivo can be alleviated with a cell-permeable succinate prodrug JI Janowska, S Piel, N Saliba, CD Kim, DH Jang, M Karlsson, TJ Kilbaugh, ... Toxicology in Vitro 65, 104794, 2020 | 15 | 2020 |
In vitro comparison of hydroxocobalamin (B12a) and the mitochondrial directed therapy by a succinate prodrug in a cellular model of cyanide poisoning S Owiredu, A Ranganathan, JC Greenwood, S Piel, JI Janowska, ... Toxicology Reports 7, 1263-1271, 2020 | 13 | 2020 |
Respiratory uncoupling by increased H+ or K+ flux is beneficial for heart mitochondrial turnover of reactive oxygen species but not for permeability transition S Morota, S Piel, MJ Hansson BMC cell biology 14, 1-10, 2013 | 11 | 2013 |
Alterations in cerebral and cardiac mitochondrial function in a porcine model of acute carbon monoxide poisoning DH Jang, S Piel, JC Greenwood, M Kelly, VM Mazandi, A Ranganathan, ... Clinical Toxicology 59 (9), 801-809, 2021 | 9 | 2021 |
Mitochondrial Physiology E Gnaiger The many Faces 158, 2005 | 7* | 2005 |
Emerging cellular-based therapies in carbon monoxide poisoning DH Jang, S Piel, JC Greenwood, JK Ehinger, TJ Kilbaugh American Journal of Physiology-Cell Physiology 321 (2), C269-C275, 2021 | 5 | 2021 |
Preliminary Research: Application of Non-Invasive Measure of Cytochrome c Oxidase Redox States and Mitochondrial Function in a Porcine Model of Carbon … A Lewis, RM Forti, O Alomaja, C Mesaros, S Piel, JC Greenwood, ... Journal of Medical Toxicology 18 (3), 214-222, 2022 | 4 | 2022 |
Alteration in cerebral metabolism in a rodent model of acute sub-lethal cyanide poisoning O Alomaja, FS Shofer, JC Greenwood, S Piel, C Clayman, C Mesaros, ... Journal of Medical Toxicology 19 (2), 196-204, 2023 | 2 | 2023 |
Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning S Piel, JI Janowska, JL Ward, MJ McManus, JS Jose, J Starr, M Sheldon, ... Scientific Reports 12 (1), 20329, 2022 | 2 | 2022 |
Succinate prodrugs for use in the treatment of lactic acidosis or drug-induced side-effects due to Complex I-related impairment of mitochondrial oxidative phosphorylation E Elmer, MJ Hansson, KHJ Ehinger, S Piel, S Moss US Patent 10,307,389, 2019 | 2 | 2019 |
Mitochondrial targeted biofuels as countermeasures against chemical threats S Piel, J Janowska, JK Ehinger, M Karlsson, TJ Kilbaugh A44. CRITICAL CARE: ONE THOUSAND AND ONE NIGHTS-NON-PULMONARY CRITICAL CARE …, 2019 | 2 | 2019 |
Mitochondrial medicine. New strategies to evaluate drug toxicity and develop pharmacological protection of the cell’s powerhouse. S Piel | 1 | 2018 |
NVP019 POTENTLY INHIBITS CYCLOPHILIN D-DEPENDENT MITOCHONDRIAL PERMEABILITY TRANSITION IN HUMAN HEART AND REDUCES MYOCARDIAL INFARCT SIZE IN MICE B Pillot, S Piel, F Derimay, A Gharib, MJ Hansson, M Ovize Journal of the American College of Cardiology 65 (10S), A159-A159, 2015 | 1 | 2015 |