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Fiona Marshall
Fiona Marshall
President Biomedical Research Novartis
Zweryfikowany adres z novartis.com
Tytuł
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The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids
AJ Brown, SM Goldsworthy, AA Barnes, MM Eilert, L Tcheang, D Daniels, ...
Journal of Biological Chemistry 278 (13), 11312-11319, 2003
24752003
Heterodimerization is required for the formation of a functional GABAB receptor
JH White, A Wise, MJ Main, A Green, NJ Fraser, GH Disney, AA Barnes, ...
Nature 396 (6712), 679-682, 1998
14981998
International Union of Pharmacology. XXXIII. Mammalian γ-aminobutyric acidB receptors: structure and function
NG Bowery, B Bettler, W Froestl, JP Gallagher, F Marshall, M Raiteri, ...
Pharmacological reviews 54 (2), 247-264, 2002
8162002
Molecular identification of high and low affinity receptors for nicotinic acid
A Wise, SM Foord, NJ Fraser, AA Barnes, N Elshourbagy, M Eilert, ...
Journal of Biological Chemistry 278 (11), 9869-9874, 2003
6512003
Structure of the adenosine A2A receptor in complex with ZM241385 and the xanthines XAC and caffeine
AS Doré, N Robertson, JC Errey, I Ng, K Hollenstein, B Tehan, E Hurrell, ...
Structure 19 (9), 1283-1293, 2011
6382011
Structure of class B GPCR corticotropin-releasing factor receptor 1
K Hollenstein, J Kean, A Bortolato, RKY Cheng, AS Doré, A Jazayeri, ...
Nature 499 (7459), 438-443, 2013
5042013
Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain
AS Doré, K Okrasa, JC Patel, M Serrano-Vega, K Bennett, RM Cooke, ...
Nature 511 (7511), 557-562, 2014
4622014
GABAB receptors–the first 7TM heterodimers
FH Marshall, KA Jones, K Kaupmann, B Bettler
Trends in pharmacological sciences 20 (10), 396-399, 1999
4541999
Generic GPCR residue numbers–aligning topology maps while minding the gaps
V Isberg, C De Graaf, A Bortolato, V Cherezov, V Katritch, FH Marshall, ...
Trends in pharmacological sciences 36 (1), 22-31, 2015
4522015
Discovery of 1,2,4-Triazine Derivatives as Adenosine A2A Antagonists using Structure Based Drug Design
M Congreve, SP Andrews, AS Doré, K Hollenstein, E Hurrell, ...
Journal of medicinal chemistry 55 (5), 1898-1903, 2012
3692012
CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain
N Clayton, FH Marshall, C Bountra, CT O'shaughnessy
Pain 96 (3), 253-260, 2002
3252002
Insights into the structure of class B GPCRs
K Hollenstein, C de Graaf, A Bortolato, MW Wang, FH Marshall, ...
Trends in pharmacological sciences 35 (1), 12-22, 2014
2662014
Progress in structure based drug design for G protein-coupled receptors
M Congreve, CJ Langmead, JS Mason, FH Marshall
Journal of medicinal chemistry 54 (13), 4283-4311, 2011
2622011
Structural insight into allosteric modulation of protease-activated receptor 2
RKY Cheng, C Fiez-Vandal, O Schlenker, K Edman, B Aggeler, DG Brown, ...
Nature 545 (7652), 112-115, 2017
2462017
A bioluminescent assay for agonist activity at potentially any G-protein-coupled receptor
J Stables, A Green, F Marshall, N Fraser, E Knight, M Sautel, G Milligan, ...
Analytical biochemistry 252 (1), 115-126, 1997
2421997
Intracellular allosteric antagonism of the CCR9 receptor
C Oswald, M Rappas, J Kean, AS Doré, JC Errey, K Bennett, F Deflorian, ...
Nature 540 (7633), 462-465, 2016
2392016
The GABAB receptor interacts directly with the related transcription factors CREB2 and ATFx
JH White, RAJ McIllhinney, A Wise, F Ciruela, WY Chan, PC Emson, ...
Proceedings of the National Academy of Sciences 97 (25), 13967-13972, 2000
2212000
Structures of human A1 and A2A adenosine receptors with xanthines reveal determinants of selectivity
RKY Cheng, E Segala, N Robertson, F Deflorian, AS Doré, JC Errey, ...
Structure 25 (8), 1275-1285. e4, 2017
2152017
Extra-helical binding site of a glucagon receptor antagonist
A Jazayeri, AS Doré, D Lamb, H Krishnamurthy, SM Southall, AH Baig, ...
Nature 533 (7602), 274-277, 2016
2082016
Crystal structure of the GLP-1 receptor bound to a peptide agonist
A Jazayeri, M Rappas, AJH Brown, J Kean, JC Errey, NJ Robertson, ...
Nature 546 (7657), 254-258, 2017
1992017
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