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Fiona Marshall
Fiona Marshall
Senior Vice President, Discovery, Preclinical and Translational medicine
Verified email at merck.com
Title
Cited by
Cited by
Year
The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids
AJ Brown, SM Goldsworthy, AA Barnes, MM Eilert, L Tcheang, D Daniels, ...
Journal of Biological Chemistry 278 (13), 11312-11319, 2003
19812003
Heterodimerization is required for the formation of a functional GABAB receptor
JH White, A Wise, MJ Main, A Green, NJ Fraser, GH Disney, AA Barnes, ...
Nature 396 (6712), 679-682, 1998
14231998
International Union of Pharmacology. XXXIII. Mammalian γ-aminobutyric acidB receptors: structure and function
NG Bowery, B Bettler, W Froestl, JP Gallagher, F Marshall, M Raiteri, ...
Pharmacological reviews 54 (2), 247-264, 2002
7572002
Molecular identification of high and low affinity receptors for nicotinic acid
A Wise, SM Foord, NJ Fraser, AA Barnes, N Elshourbagy, M Eilert, ...
Journal of Biological Chemistry 278 (11), 9869-9874, 2003
6052003
Structure of the adenosine A2A receptor in complex with ZM241385 and the xanthines XAC and caffeine
AS Doré, N Robertson, JC Errey, I Ng, K Hollenstein, B Tehan, E Hurrell, ...
Structure 19 (9), 1283-1293, 2011
5562011
Structure of class B GPCR corticotropin-releasing factor receptor 1
K Hollenstein, J Kean, A Bortolato, RKY Cheng, AS Doré, A Jazayeri, ...
Nature 499 (7459), 438-443, 2013
4542013
GABAB receptors–the first 7TM heterodimers
FH Marshall, KA Jones, K Kaupmann, B Bettler
Trends in pharmacological sciences 20 (10), 396-399, 1999
4371999
Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain
AS Doré, K Okrasa, JC Patel, M Serrano-Vega, K Bennett, RM Cooke, ...
Nature 511 (7511), 557-562, 2014
4002014
Discovery of 1,2,4-Triazine Derivatives as Adenosine A2A Antagonists using Structure Based Drug Design
M Congreve, SP Andrews, AS Doré, K Hollenstein, E Hurrell, ...
Journal of medicinal chemistry 55 (5), 1898-1903, 2012
3332012
Generic GPCR residue numbers–aligning topology maps while minding the gaps
V Isberg, C De Graaf, A Bortolato, V Cherezov, V Katritch, FH Marshall, ...
Trends in pharmacological sciences 36 (1), 22-31, 2015
3192015
CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain
N Clayton, FH Marshall, C Bountra, CT O'shaughnessy
Pain 96 (3), 253-260, 2002
2842002
Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study
DN Wijeysundera, RM Pearse, MA Shulman, TEF Abbott, E Torres, ...
The Lancet 391 (10140), 2631-2640, 2018
2422018
Progress in structure based drug design for G protein-coupled receptors
M Congreve, CJ Langmead, JS Mason, FH Marshall
Journal of medicinal chemistry 54 (13), 4283-4311, 2011
2412011
A bioluminescent assay for agonist activity at potentially any G-protein-coupled receptor
J Stables, A Green, F Marshall, N Fraser, E Knight, M Sautel, G Milligan, ...
Analytical biochemistry 252 (1), 115-126, 1997
2341997
Insights into the structure of class B GPCRs
K Hollenstein, C de Graaf, A Bortolato, MW Wang, FH Marshall, ...
Trends in pharmacological sciences 35 (1), 12-22, 2014
2182014
The GABAB receptor interacts directly with the related transcription factors CREB2 and ATFx
JH White, RAJ McIllhinney, A Wise, F Ciruela, WY Chan, PC Emson, ...
Proceedings of the National Academy of Sciences 97 (25), 13967-13972, 2000
2162000
RAMPs: accessory proteins for seven transmembrane domain receptors
SM Foord, FH Marshall
Trends in pharmacological sciences 20 (5), 184-187, 1999
1871999
Extra-helical binding site of a glucagon receptor antagonist
A Jazayeri, AS Doré, D Lamb, H Krishnamurthy, SM Southall, AH Baig, ...
Nature 533 (7602), 274-277, 2016
1832016
Intracellular allosteric antagonism of the CCR9 receptor
C Oswald, M Rappas, J Kean, AS Doré, JC Errey, K Bennett, F Deflorian, ...
Nature 540 (7633), 462-465, 2016
1812016
New insights from structural biology into the druggability of G protein-coupled receptors
JS Mason, A Bortolato, M Congreve, FH Marshall
Trends in pharmacological sciences 33 (5), 249-260, 2012
1752012
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