Dynamic control of plant water use using designed ABA receptor agonists AS Vaidya, JDM Helander, FC Peterson, D Elzinga, W Dejonghe, ... Science 366 (6464), eaaw8848, 2019 | 118 | 2019 |
A rationally designed agonist defines subfamily IIIA abscisic acid receptors as critical targets for manipulating transpiration AS Vaidya, FC Peterson, D Yarmolinsky, E Merilo, I Verstraeten, SY Park, ... ACS Chemical Biology 12 (11), 2842-2848, 2017 | 67 | 2017 |
Chemical manipulation of plant water use JDM Helander, AS Vaidya, SR Cutler Bioorganic & Medicinal Chemistry 24 (3), 493-500, 2016 | 62 | 2016 |
A chimeric SERM–histone deacetylase inhibitor approach to breast cancer therapy HK Patel, MI Siklos, H Abdelkarim, EL Mendonca, A Vaidya, PA Petukhov, ... ChemMedChem 9 (3), 602-613, 2014 | 25 | 2014 |
Novel histone deacetylase 8 ligands without a zinc chelating group: Exploring an ‘upside-down’binding pose AS Vaidya, R Neelarapu, A Madriaga, H Bai, E Mendonca, H Abdelkarim, ... Bioorganic & medicinal chemistry letters 22 (21), 6621-6627, 2012 | 24 | 2012 |
Defining and exploiting hypersensitivity hotspots to facilitate abscisic acid agonist optimization D Elzinga, E Sternburg, D Sabbadin, M Bartsch, SY Park, A Vaidya, ... ACS chemical biology 14 (3), 332-336, 2019 | 23 | 2019 |
Design, synthesis, modeling, biological evaluation and photoaffinity labeling studies of novel series of photoreactive benzamide probes for histone deacetylase 2 AS Vaidya, B Karumudi, E Mendonca, A Madriaga, H Abdelkarim, ... Bioorganic & medicinal chemistry letters 22 (15), 5025-5030, 2012 | 21 | 2012 |
Click-to-lead design of a picomolar ABA receptor antagonist with potent activity in vivo AS Vaidya, FC Peterson, J Eckhardt, Z Xing, SY Park, W Dejonghe, ... Proceedings of the National Academy of Sciences 118 (38), e2108281118, 2021 | 16 | 2021 |
Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Amine‐based Histone Deacetylase Inhibitors H Abdelkarim, R Neelarapu, A Madriaga, AS Vaidya, I Kastrati, ... ChemMedChem 12 (24), 2030-2043, 2017 | 10 | 2017 |
Selective control of parasitic nematodes using bioactivated nematicides AR Burns, RJ Baker, M Kitner, J Knox, B Cooke, JR Volpatti, AS Vaidya, ... Nature, 1-8, 2023 | 5 | 2023 |
Chemical approaches for improving plant water use AS Vaidya, SR Cutler Abscisic Acid: Methods and Protocols, 221-230, 2022 | 4 | 2022 |
A luciferase reporter assay to identify chemical activators of ABA signaling I García-Maquilón, PL Rodriguez, AS Vaidya, J Lozano-Juste Plant Chemical Genomics: Methods and Protocols, 113-121, 2021 | 4 | 2021 |
Egg-laying and locomotory screens with C. elegans yield a nematode-selective small molecule stimulator of neurotransmitter release S Harrington, JJ Knox, AR Burns, KL Choo, A Au, M Kitner, C Haeberli, ... Communications Biology 5 (1), 865, 2022 | 3 | 2022 |
PYL10 bound to the ABA pan-antagonist 4a FC Peterson, AS Vaidya, BF Volkman, SR Cutler (No Title), 2021 | 2 | 2021 |
Synthesis and characterization of abscisic acid receptor modulators AS Vaidya, SY Park, Z Xing, SR Cutler Methods in Enzymology 671, 435-470, 2022 | 1 | 2022 |
In Planta Labeling Using a Clickable ER-Disrupting Probe Suggests a Role for Oleosins in Arabidopsis Seedling ER Integrity W Dejonghe, AS Vaidya, SE Alfred, SR Cutler ACS Chemical Biology 16 (11), 2151-2157, 2021 | 1 | 2021 |
Unusually potent ABA receptor pan-antagonists SR Cutler, A Vaidya US Patent 11,641,857, 2023 | | 2023 |
Nementin is a Nematode-Selective Small Molecule Agonist of Neurotransmitter Release S Harrington, JJ Knox, AR Burns, KL Choo, A Au, M Kitner, C Haeberli, ... bioRxiv, 2022.03. 12.484074, 2022 | | 2022 |
INAUGURAL ARTICLE by a Recently Elected Academy Member: Click-to-lead design of a picomolar ABA receptor antagonist with potent activity in vivo AS Vaidya, FC Peterson, J Eckhardt, Z Xing, SY Park, W Dejonghe, ... Proceedings of the National Academy of Sciences of the United States of …, 2021 | | 2021 |
Overpowered aba receptor agonists SR Cutler, A Vaidya, J Helander US Patent App. 17/135,194, 2021 | | 2021 |