Obserwuj
John Fryer
John Fryer
Professor, Associate Dean, Mayo Clinic
Zweryfikowany adres z mayo.edu
Tytuł
Cytowane przez
Cytowane przez
Rok
TIA1 mutations in amyotrophic lateral sclerosis and frontotemporal dementia promote phase separation and alter stress granule dynamics
IR Mackenzie, AM Nicholson, M Sarkar, J Messing, MD Purice, C Pottier, ...
Neuron 95 (4), 808-816. e9, 2017
5592017
ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE
SE Wahrle, H Jiang, M Parsadanian, J Legleiter, X Han, JD Fryer, ...
Journal of Biological Chemistry 279 (39), 40987-40993, 2004
5282004
Apolipoprotein E is a ligand for triggering receptor expressed on myeloid cells 2 (TREM2)
Y Atagi, CC Liu, MM Painter, XF Chen, C Verbeeck, H Zheng, X Li, ...
Journal of Biological Chemistry 290 (43), 26043-26050, 2015
4782015
C9ORF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits
J Chew, TF Gendron, M Prudencio, H Sasaguri, YJ Zhang, ...
Science 348 (6239), 1151-1154, 2015
4532015
Diet and exercise orthogonally alter the gut microbiome and reveal independent associations with anxiety and cognition
SS Kang, PR Jeraldo, A Kurti, MEB Miller, MD Cook, K Whitlock, ...
Molecular neurodegeneration 9, 1-12, 2014
3572014
Noncompetitive functional inhibition at diverse, human nicotinic acetylcholine receptor subtypes by bupropion, phencyclidine, and ibogaine
JD Fryer, RJ Lukas
Journal of Pharmacology and Experimental Therapeutics 288 (1), 88-92, 1999
3511999
ATAXIN-1 interacts with the repressor Capicua in its native complex to cause SCA1 neuropathology
YC Lam, AB Bowman, P Jafar-Nejad, J Lim, R Richman, JD Fryer, ...
Cell 127 (7), 1335-1347, 2006
3502006
C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins
YJ Zhang, TF Gendron, JC Grima, H Sasaguri, K Jansen-West, YF Xu, ...
Nature neuroscience 19 (5), 668-677, 2016
3182016
Human apolipoprotein E4 alters the amyloid-β 40: 42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model
JD Fryer, K Simmons, M Parsadanian, KR Bales, SM Paul, PM Sullivan, ...
Journal of Neuroscience 25 (11), 2803-2810, 2005
3162005
Soluble TREM2 induces inflammatory responses and enhances microglial survival
L Zhong, XF Chen, T Wang, Z Wang, C Liao, Z Wang, R Huang, D Wang, ...
Journal of Experimental Medicine 214 (3), 597-607, 2017
2872017
TREM2 promotes microglial survival by activating Wnt/β-catenin pathway
H Zheng, L Jia, CC Liu, Z Rong, L Zhong, L Yang, XF Chen, JD Fryer, ...
Journal of Neuroscience 37 (7), 1772-1784, 2017
2822017
Voluntary and forced exercise differentially alters the gut microbiome in C57BL/6J mice
JM Allen, MEB Miller, BD Pence, K Whitlock, V Nehra, HR Gaskins, ...
Journal of applied physiology, 2015
2772015
Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis
YJ Zhang, TF Gendron, MTW Ebbert, AD O’Raw, M Yue, K Jansen-West, ...
Nature medicine 24 (8), 1136-1142, 2018
2712018
Large-scale topology and the default mode network in the mouse connectome
JM Stafford, BR Jarrett, O Miranda-Dominguez, BD Mills, N Cain, ...
Proceedings of the National Academy of Sciences 111 (52), 18745-18750, 2014
2622014
Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice
M Yue, KM Hinkle, P Davies, E Trushina, FC Fiesel, TA Christenson, ...
Neurobiology of disease 78, 172-195, 2015
2502015
Clusterin contributes to caspase-3–independent brain injury following neonatal hypoxia-ischemia
BH Han, RB DeMattos, LL Dugan, JS Kim-Han, RP Brendza, JD Fryer, ...
Nature medicine 7 (3), 338-343, 2001
2472001
Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice
RB DeMattos, RP Brendza, JE Heuser, M Kierson, JR Cirrito, J Fryer, ...
Neurochemistry international 39 (5-6), 415-425, 2001
2252001
Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis
TF Gendron, J Chew, JN Stankowski, LR Hayes, YJ Zhang, M Prudencio, ...
Science translational medicine 9 (383), eaai7866, 2017
2232017
A partial loss of function allele of Methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome
RC Samaco, JD Fryer, J Ren, S Fyffe, HT Chao, Y Sun, JJ Greer, ...
Human molecular genetics 17 (12), 1718-1727, 2008
2132008
Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity
YJ Zhang, L Guo, PK Gonzales, TF Gendron, Y Wu, K Jansen-West, ...
Science 363 (6428), eaav2606, 2019
2082019
Nie można teraz wykonać tej operacji. Spróbuj ponownie później.
Prace 1–20