| GPCRdb in 2018: adding GPCR structure models and ligands G Pándy-Szekeres, C Munk, TM Tsonkov, S Mordalski, K Harpsøe, ... Nucleic acids research 46 (D1), D440-D446, 2018 | 562 | 2018 |
| GPCRdb: an information system for G protein-coupled receptors V Isberg, S Mordalski, C Munk, K Rataj, K Harpsøe, AS Hauser, B Vroling, ... Nucleic acids research 44 (D1), D356-D364, 2016 | 465 | 2016 |
| 5-HT2C receptor structures reveal the structural basis of GPCR polypharmacology Y Peng, JD McCorvy, K Harpsøe, K Lansu, S Yuan, P Popov, L Qu, M Pu, ... Cell 172 (4), 719-730. e14, 2018 | 241 | 2018 |
| GPCRdb: the G protein‐coupled receptor database–an introduction C Munk, V Isberg, S Mordalski, K Harpsøe, K Rataj, AS Hauser, P Kolb, ... British Journal of Pharmacology 173 (14), 2195-2207, 2016 | 240 | 2016 |
| Structural insights into the lipid and ligand regulation of serotonin receptors P Xu, S Huang, H Zhang, C Mao, XE Zhou, X Cheng, IA Simon, DD Shen, ... Nature 592 (7854), 469-473, 2021 | 194 | 2021 |
| Unraveling the high-and low-sensitivity agonist responses of nicotinic acetylcholine receptors K Harpsøe, PK Ahring, JK Christensen, ML Jensen, D Peters, T Balle Journal of Neuroscience 31 (30), 10759-10766, 2011 | 162 | 2011 |
| Total synthesis and structure–activity relationship studies of a series of selective G protein inhibitors XF Xiong, H Zhang, CR Underwood, K Harpsøe, TJ Gardella, MF Wöldike, ... Nature chemistry 8 (11), 1035-1041, 2016 | 81 | 2016 |
| GPCRs steer Gi and Gs selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors S Huang, P Xu, DD Shen, IA Simon, C Mao, Y Tan, H Zhang, K Harpsøe, ... Molecular cell 82 (14), 2681-2695. e6, 2022 | 78 | 2022 |
| Structural proof of a dimeric positive modulator bridging two identical AMPA receptor-binding sites BH Kaae, K Harpsøe, JS Kastrup, AC Sanz, DS Pickering, B Metzler, ... Chemistry & biology 14 (11), 1294-1303, 2007 | 71 | 2007 |
| Rational design of α-conotoxin analogues targeting α7 nicotinic acetylcholine receptors C Armishaw, AA Jensen, T Balle, RJ Clark, K Harpsøe, C Skonberg, ... Journal of Biological Chemistry 284 (14), 9498-9512, 2009 | 61 | 2009 |
| Integrating structural and mutagenesis data to elucidate GPCR ligand binding C Munk, K Harpsøe, AS Hauser, V Isberg, DE Gloriam Current opinion in pharmacology 30, 51-58, 2016 | 57 | 2016 |
| Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine α4β2 receptors LAH Rohde, PK Ahring, ML Jensen, EØ Nielsen, D Peters, C Helgstrand, ... Journal of Biological Chemistry 287 (6), 4248-4259, 2012 | 56 | 2012 |
| GPCRdb: an information system for G protein-coupled receptors V Isberg, S Mordalski, C Munk, K Rataj, K Harpsøe, AS Hauser, B Vroling, ... Nucleic Acids Research 45 (5), 2936-2936, 2017 | 52 | 2017 |
| Selective negative allosteric modulation of metabotropic glutamate receptors–a structural perspective of ligands and mutants K Harpsøe, V Isberg, BG Tehan, D Weiss, A Arsova, FH Marshall, ... Scientific reports 5 (1), 13869, 2015 | 46 | 2015 |
| Rational design of a heterotrimeric G protein α subunit with artificial inhibitor sensitivity D Malfacini, J Patt, S Annala, K Harpsøe, F Eryilmaz, R Reher, ... Journal of Biological Chemistry 294 (15), 5747-5758, 2019 | 44 | 2019 |
| Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide MG Di Giglio, M Muttenthaler, K Harpsøe, Z Liutkeviciute, P Keov, T Eder, ... Scientific Reports 7 (1), 41002, 2017 | 42 | 2017 |
| mGluR5: exploration of orthosteric and allosteric ligand binding pockets and their applications to drug discovery C Mølck, K Harpsøe, DE Gloriam, JM Mathiesen, SM Nielsen, ... Neurochemical research 39, 1862-1875, 2014 | 38 | 2014 |
| Pharmacological characterization and modeling of the binding sites of novel 1, 3-bis (pyridinylethynyl) benzenes as metabotropic glutamate receptor 5-selective negative … C Mølck, K Harpsøe, DE Gloriam, RP Clausen, U Madsen, LØ Pedersen, ... Molecular pharmacology 82 (5), 929-937, 2012 | 37 | 2012 |
| Structure–activity relationship and conformational studies of the natural product cyclic depsipeptides YM-254890 and FR900359 H Zhang, AL Nielsen, MW Boesgaard, K Harpsøe, NL Daly, XF Xiong, ... European journal of medicinal chemistry 156, 847-860, 2018 | 34 | 2018 |
| Discovery of a novel allosteric modulator of 5-HT3 receptors: inhibition and potentiation of Cys-loop receptor signaling through a conserved transmembrane intersubunit site SM Trattnig, K Harpsøe, SB Thygesen, LM Rahr, PK Ahring, T Balle, ... Journal of Biological Chemistry 287 (30), 25241-25254, 2012 | 34 | 2012 |
Alexander Sebastian HauserUniversity of CopenhagenZweryfikowany adres z alumni.ku.dk
