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Andrew J Rowan
Andrew J Rowan
Principal Laboratory Research Scientist, Francis Crick Institute
Zweryfikowany adres z crick.ac.uk
Tytuł
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Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
M Gerlinger, AJ Rowan, S Horswell, J Larkin, D Endesfelder, E Gronroos, ...
New England journal of medicine 366 (10), 883-892, 2012
85782012
Tracking the evolution of non–small-cell lung cancer
M Jamal-Hanjani, GA Wilson, N McGranahan, NJ Birkbak, TBK Watkins, ...
New England Journal of Medicine 376 (22), 2109-2121, 2017
22012017
Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer
IPM Tomlinson, NA Alam, AJ Rowan, E Barclay, EEM Jaeger, D Kelsell, ...
Nature genetics 30 (4), 406, 2002
17382002
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ...
Nature 545 (7655), 446-451, 2017
17222017
p53 mutations in colorectal cancer.
NR Rodrigues, A Rowan, ME Smith, IB Kerr, WF Bodmer, JV Gannon, ...
Proceedings of the National Academy of Sciences 87 (19), 7555-7559, 1990
13821990
Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
M Gerlinger, S Horswell, J Larkin, AJ Rowan, MP Salm, I Varela, R Fisher, ...
Nature genetics 46 (3), 225-233, 2014
13692014
Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
EC De Bruin, N McGranahan, R Mitter, M Salm, DC Wedge, L Yates, ...
Science 346 (6206), 251-256, 2014
12512014
Allele-specific HLA loss and immune escape in lung cancer evolution
N McGranahan, R Rosenthal, CT Hiley, AJ Rowan, TBK Watkins, ...
Cell 171 (6), 1259-1271. e11, 2017
11782017
A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24. 21
I Tomlinson, E Webb, L Carvajal-Carmona, P Broderick, Z Kemp, S Spain, ...
Nature genetics 39 (8), 984-988, 2007
9332007
Replication stress links structural and numerical cancer chromosomal instability
RA Burrell, SE McClelland, D Endesfelder, P Groth, MC Weller, N Shaikh, ...
Nature 494 (7438), 492-496, 2013
9162013
Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis
S Turajlic, K Litchfield, H Xu, R Rosenthal, N McGranahan, JL Reading, ...
The lancet oncology 18 (8), 1009-1021, 2017
8652017
Tracking cancer evolution reveals constrained routes to metastases: TRACERx renal
S Turajlic, H Xu, K Litchfield, A Rowan, T Chambers, JI Lopez, D Nicol, ...
Cell 173 (3), 581-594. e12, 2018
7182018
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23. 3
IPM Tomlinson, E Webb, L Carvajal-Carmona, P Broderick, K Howarth, ...
Nature genetics 40 (5), 623-630, 2008
6552008
β-Catenin mutations in cell lines established from human colorectal cancers
M Ilyas, IPM Tomlinson, A Rowan, M Pignatelli, WF Bodmer
Proceedings of the National Academy of Sciences 94 (19), 10330-10334, 1997
6211997
APC mutations in sporadic colorectal tumors: A mutational “hotspot” and interdependence of the “two hits”
AJ Rowan, H Lamlum, M Ilyas, J Wheeler, J Straub, A Papadopoulou, ...
Proceedings of the National Academy of Sciences 97 (7), 3352-3357, 2000
6182000
A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk
P Broderick, L Carvajal-Carmona, AM Pittman, E Webb, K Howarth, ...
Nature genetics 39 (11), 1315-1317, 2007
6112007
Meta-analysis of tumor-and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition
K Litchfield, JL Reading, C Puttick, K Thakkar, C Abbosh, R Bentham, ...
Cell 184 (3), 596-614. e14, 2021
5792021
Deterministic evolutionary trajectories influence primary tumor growth: TRACERx renal
S Turajlic, H Xu, K Litchfield, A Rowan, S Horswell, T Chambers, ...
Cell 173 (3), 595-610. e11, 2018
5522018
Fc effector function contributes to the activity of human anti-CTLA-4 antibodies
FA Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ...
Cancer cell 33 (4), 649-663. e4, 2018
5432018
Chromosomal instability confers intrinsic multidrug resistance
AJX Lee, D Endesfelder, AJ Rowan, A Walther, NJ Birkbak, PA Futreal, ...
Cancer research 71 (5), 1858-1870, 2011
5172011
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