Phagocytosis: receptors, signal integration, and the cytoskeleton SA Freeman, S Grinstein Immunological reviews 262 (1), 193-215, 2014 | 621 | 2014 |
VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis R Hua, D Cheng, É Coyaud, S Freeman, E Di Pietro, Y Wang, A Vissa, ... Journal of Cell Biology 216 (2), 367-377, 2017 | 263 | 2017 |
Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation Y Leng, J Zhang, K Badour, E Arpaia, S Freeman, P Cheung, M Siu, ... Proceedings of the National Academy of Sciences 102 (4), 1098-1103, 2005 | 253 | 2005 |
Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins D Schlam, RD Bagshaw, SA Freeman, RF Collins, T Pawson, GD Fairn, ... Nature communications 6 (1), 8623, 2015 | 227 | 2015 |
Transmembrane pickets connect cyto-and pericellular skeletons forming barriers to receptor engagement SA Freeman, A Vega, M Riedl, RF Collins, PP Ostrowski, EC Woods, ... Cell 172 (1), 305-317. e10, 2018 | 214 | 2018 |
Integrins form an expanding diffusional barrier that coordinates phagocytosis SA Freeman, J Goyette, W Furuya, EC Woods, CR Bertozzi, W Bergmeier, ... Cell 164 (1), 128-140, 2016 | 207 | 2016 |
(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells D Barsyte-Lovejoy, F Li, MJ Oudhoff, JH Tatlock, A Dong, H Zeng, H Wu, ... Proceedings of the National Academy of Sciences 111 (35), 12853-12858, 2014 | 190 | 2014 |
Control of the hippo pathway by Set7-dependent methylation of Yap MJ Oudhoff, SA Freeman, AL Couzens, F Antignano, E Kuznetsova, ... Developmental cell 26 (2), 188-194, 2013 | 182 | 2013 |
Interaction of the Wiskott–Aldrich syndrome protein with sorting nexin 9 is required for CD28 endocytosis and cosignaling in T cells K Badour, MKH McGavin, J Zhang, S Freeman, C Vieira, D Filipp, M Julius, ... Proceedings of the National Academy of Sciences 104 (5), 1593-1598, 2007 | 145 | 2007 |
The cytoskeleton in phagocytosis and macropinocytosis S Mylvaganam, SA Freeman, S Grinstein Current Biology 31 (10), R619-R632, 2021 | 141 | 2021 |
Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance SA Freeman, S Uderhardt, A Saric, RF Collins, CM Buckley, ... Science 367 (6475), 301-305, 2020 | 131 | 2020 |
Cofilin-mediated F-actin severing is regulated by the Rap GTPase and controls the cytoskeletal dynamics that drive lymphocyte spreading and BCR microcluster formation SA Freeman, V Lei, M Dang-Lawson, K Mizuno, CD Roskelley, MR Gold The Journal of Immunology 187 (11), 5887-5900, 2011 | 127 | 2011 |
The rap GTPases regulate B cell morphology, immune-synapse formation, and signaling by particulate B cell receptor ligands KBL Lin, SA Freeman, S Zabetian, H Brugger, M Weber, V Lei, ... Immunity 28 (1), 75-87, 2008 | 122 | 2008 |
Phagocytosis by the retinal pigment epithelium: recognition, resolution, recycling W Kwon, SA Freeman Frontiers in immunology 11, 604205, 2020 | 110 | 2020 |
SETD7 controls intestinal regeneration and tumorigenesis by regulating Wnt/β-catenin and Hippo/YAP signaling MJ Oudhoff, MJS Braam, SA Freeman, D Wong, DG Rattray, J Wang, ... Developmental cell 37 (1), 47-57, 2016 | 107 | 2016 |
Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor SA Freeman, V Jaumouillé, K Choi, BE Hsu, HS Wong, L Abraham, ... Nature communications 6 (1), 6168, 2015 | 104 | 2015 |
Lipid peroxidation increases membrane tension, Piezo1 gating, and cation permeability to execute ferroptosis Y Hirata, R Cai, A Volchuk, BE Steinberg, Y Saito, A Matsuzawa, ... Current Biology 33 (7), 1282-1294. e5, 2023 | 84 | 2023 |
Diffusion barriers, mechanical forces, and the biophysics of phagocytosis PP Ostrowski, S Grinstein, SA Freeman Developmental cell 38 (2), 135-146, 2016 | 79 | 2016 |
Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice L Wang, D Aschenbrenner, Z Zeng, X Cao, D Mayr, M Mehta, M Capitani, ... Nature genetics 53 (4), 500-510, 2021 | 77 | 2021 |
Multistep track segmentation and motion classification for transient mobility analysis AR Vega, SA Freeman, S Grinstein, K Jaqaman Biophysical journal 114 (5), 1018-1025, 2018 | 74 | 2018 |