| Kinetic investigations of the role of factor inhibiting hypoxia-inducible factor (FIH) as an oxygen sensor H Tarhonskaya, AP Hardy, EA Howe, ND Loik, HB Kramer, ... Journal of Biological Chemistry 290 (32), 19726-19742, 2015 | 88 | 2015 |
| Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases H Tarhonskaya, AM Rydzik, IKH Leung, ND Loik, MC Chan, A Kawamura, ... Nature communications 5 (1), 3423, 2014 | 83 | 2014 |
| Ribonucleotide reductase requires subunit switching in hypoxia to maintain DNA replication IP Foskolou, C Jorgensen, KB Leszczynska, MM Olcina, H Tarhonskaya, ... Molecular cell 66 (2), 206-220. e9, 2017 | 79 | 2017 |
| Biochemical characterization of New Delhi metallo-β-lactamase variants reveals differences in protein stability A Makena, J Brem, I Pfeffer, REJ Geffen, SE Wilkins, H Tarhonskaya, ... Journal of antimicrobial chemotherapy 70 (2), 463-469, 2015 | 71 | 2015 |
| Investigations on the oxygen dependence of a 2-oxoglutarate histone demethylase EM Sánchez-Fernández, H Tarhonskaya, K Al-Qahtani, RJ Hopkinson, ... Biochemical Journal 449 (2), 491-496, 2013 | 67 | 2013 |
| Investigating the contribution of the active site environment to the slow reaction of hypoxia-inducible factor prolyl hydroxylase domain 2 with oxygen H Tarhonskaya, R Chowdhury, IKH Leung, ND Loik, JSO McCullagh, ... Biochemical Journal 463 (3), 363-372, 2014 | 53 | 2014 |
| Studies on deacetoxycephalosporin C synthase support a consensus mechanism for 2-oxoglutarate dependent oxygenases H Tarhonskaya, A Szöllössi, IKH Leung, JT Bush, L Henry, ... Biochemistry 53 (15), 2483-2493, 2014 | 51 | 2014 |
| Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases CC Thinnes, A Tumber, C Yapp, G Scozzafava, T Yeh, MC Chan, TA Tran, ... Chemical communications 51 (84), 15458-15461, 2015 | 49 | 2015 |
| Studying the active-site loop movement of the São Paolo metallo-β-lactamase-1 J Brem, WB Struwe, AM Rydzik, H Tarhonskaya, I Pfeffer, E Flashman, ... Chemical science 6 (2), 956-963, 2015 | 42 | 2015 |
| Studies on the interaction of the histone demethylase KDM5B with tricarboxylic acid cycle intermediates H Tarhonskaya, RP Nowak, C Johansson, A Szykowska, A Tumber, ... Journal of Molecular Biology 429 (19), 2895-2906, 2017 | 37 | 2017 |
| The clinically used iron chelator deferasirox is an inhibitor of epigenetic JumonjiC domain-containing histone demethylases M Roatsch, I Hoffmann, MI Abboud, RL Hancock, H Tarhonskaya, KF Hsu, ... ACS Chemical Biology 14 (8), 1737-1750, 2019 | 29 | 2019 |
| Structure and mechanism of a viral collagen prolyl hydroxylase JE Longbotham, C Levy, LO Johannissen, H Tarhonskaya, S Jiang, ... Biochemistry 54 (39), 6093-6105, 2015 | 28 | 2015 |
| Use of ferrous iron by metallo-β-lactamases ST Cahill, H Tarhonskaya, AM Rydzik, E Flashman, MA McDonough, ... Journal of inorganic biochemistry 163, 185-193, 2016 | 22 | 2016 |
| Synthesis and Biological Evaluation of Tripartin, a Putative KDM4 Natural Product Inhibitor, and 1‐Dichloromethylinden‐1‐ol Analogues L Guillade, F Sarno, H Tarhonskaya, A Nebbioso, S Alvarez, A Kawamura, ... ChemMedChem 13 (18), 1949-1956, 2018 | 15 | 2018 |
| Born to sense: biophysical analyses of the oxygen sensing prolyl hydroxylase from the simplest animal Trichoplax adhaerens K Lippl, A Boleininger, MA McDonough, MI Abboud, H Tarhonskaya, ... Hypoxia, 57-71, 2018 | 13 | 2018 |
| Studying the active-site loop movement of the Sao Paolo metallo--lactamase-1. Chem Sci 6: 956–963 J Brem, WB Struwe, AM Rydzik, H Tarhonskaya, I Pfeffer, E Flashman, ... | 8 | 2015 |
| YcfDRM is a thermophilic oxygen-dependent ribosomal protein uL16 oxygenase R Sekirnik, SE Wilkins, J Bush, H Tarhonskaya, M Münzel, A Hussein, ... Extremophiles 22, 553-562, 2018 | 7 | 2018 |
| In Vitro Enzyme Assays for JmjC‐Domain‐Containing Lysine Histone Demethylases (JmjC‐KDMs) H Tarhonskaya, A Tumber, A Kawamura, CJ Schofield Current Protocols in Pharmacology 80 (1), 3.15. 1-3.15. 12, 2018 | 5 | 2018 |
| The Clinically Used Iron Chelator Deferasirox is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone Demethylases M Jung, M Roatsch, I Hoffmann, MI Abboud, RL Hancock, H Tarhonskaya, ... | | 2019 |
| Kinetic and mechanistic studies of oxygen sensing Fe (II)/2-oxoglutarate dependent oxygenases H Tarhonskaya Oxford University, UK, 2014 | | 2014 |
