Laurence C Eisenlohr
Laurence C Eisenlohr
Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania
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The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
T Fernandes-Alnemri, JW Yu, C Juliana, L Solorzano, S Kang, J Wu, ...
Nature immunology 11 (5), 385-393, 2010
Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses
N Pardi, MJ Hogan, MS Naradikian, K Parkhouse, DW Cain, L Jones, ...
Journal of Experimental Medicine 215 (6), 1571-1588, 2018
Intratumoral recombinant GM-CSF-encoding virus as gene therapy in patients with cutaneous melanoma
MJ Mastrangelo, HC Maguire, LC Eisenlohr, CE Laughlin, CE Monken, ...
Cancer gene therapy 6 (5), 409-422, 1999
SARS-CoV-2 mRNA vaccines foster potent antigen-specific germinal center responses associated with neutralizing antibody generation
K Lederer, D Castaño, DG Atria, TH Oguin, S Wang, TB Manzoni, ...
Immunity 53 (6), 1281-1295. e5, 2020
A single immunization with nucleoside-modified mRNA vaccines elicits strong cellular and humoral immune responses against SARS-CoV-2 in mice
D Laczkó, MJ Hogan, SA Toulmin, P Hicks, K Lederer, BT Gaudette, ...
Immunity 53 (4), 724-732. e7, 2020
Impaired assembly yet normal trafficking of MHC class I molecules in Tapasin mutant mice
AG Grandea, TN Golovina, SE Hamilton, V Sriram, T Spies, ...
Immunity 13 (2), 213-222, 2000
Antigen processing in vivo and the elicitation of primary CTL responses.
NP Restifo, I Bacik, KR Irvine, JW Yewdell, BJ McCabe, RW Anderson, ...
Journal of immunology (Baltimore, Md.: 1950) 154 (9), 4414-4422, 1995
MHC affinity, peptide liberation, T cell repertoire, and immunodominance all contribute to the paucity of MHC class I-restricted peptides recognized by antiviral CTL.
Y Deng, JW Yewdell, LC Eisenlohr, JR Bennink
Journal of immunology (Baltimore, Md.: 1950) 158 (4), 1507-1515, 1997
Flanking sequences influence the presentation of an endogenously synthesized peptide to cytotoxic T lymphocytes.
LC Eisenlohr, JW Yewdell, JR Bennink
The Journal of experimental medicine 175 (2), 481-487, 1992
The immunogenicity of a new human minor histocompatibility antigen results from differential antigen processing
AG Brickner, EH Warren, JA Caldwell, Y Akatsuka, TN Golovina, ...
The Journal of experimental medicine 193 (2), 195-206, 2001
The induction of virus-specific CTL as a function of increasing epitope expression: responses rise steadily until excessively high levels of epitope are attained
EJ Wherry, KA Puorro, A Porgador, LC Eisenlohr
The Journal of Immunology 163 (7), 3735-3745, 1999
Antigen presentation requires transport of MHC class I molecules from the endoplasmic reticulum
JH Cox, JW Yewdell, LC Eisenlohr, PR Johnson, JR Bennink
Science 247 (4943), 715-718, 1990
A cytosolic pathway for MHC class II–restricted antigen processing that is proteasome and TAP dependent
MK Tewari, G Sinnathamby, D Rajagopal, LC Eisenlohr
Nature immunology 6 (3), 287-294, 2005
Expression of a membrane protease enhances presentation of endogenous antigens to MHC class I-restricted T lymphocytes
LC Eiseniohr, I Bacik, JR Bennink, K Bernstein, JW Yewdell
Cell 71 (6), 963-972, 1992
The HA-2 minor histocompatibility antigen is derived from a diallelic gene encoding a novel human class I myosin protein
RA Pierce, ED Field, T Mutis, TN Golovina, CV Kap-Herr, J Pool, ...
The Journal of Immunology 167 (6), 3223-3230, 2001
The adenovirus capsid protein hexon contains a highly conserved human CD4+ T-cell epitope
M Olive, L Eisenlohr, N Flomenberg, S Hsu, P Flomenberg
Human gene therapy 13 (10), 1167-1178, 2002
Dependence of both spontaneous and antibody-dependent, granule exocytosis-mediated NK cell cytotoxicity on extracellular signal-regulated kinases
R Trotta, KA Puorro, M Paroli, L Azzoni, B Abebe, LC Eisenlohr, ...
The Journal of Immunology 161 (12), 6648-6656, 1998
The minor histocompatibility antigen HA-3 arises from differential proteasome–mediated cleavage of the lymphoid blast crisis (Lbc) oncoprotein
E Spierings, AG Brickner, JA Caldwell, S Zegveld, N Tatsis, E Blokland, ...
Blood 102 (2), 621-629, 2003
Generation of CD8+ T cell memory in response to low, high, and excessive levels of epitope
EJ Wherry, MJ McElhaugh, LC Eisenlohr
The Journal of Immunology 168 (9), 4455-4461, 2002
Ribosomal scanning past the primary initiation codon as a mechanism for expression of CTL epitopes encoded in alternative reading frames.
TN Bullock, LC Eisenlohr
The Journal of experimental medicine 184 (4), 1319-1329, 1996
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