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SIMONE MAZZAFERRO
SIMONE MAZZAFERRO
University of Cambridge
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Cited by
Cited by
Year
Additional acetylcholine (ACh) binding site at α4/α4 interface of (α4β2) 2α4 nicotinic receptor influences agonist sensitivity
S Mazzaferro, N Benallegue, A Carbone, F Gasparri, R Vijayan, ...
Journal of Biological Chemistry 286 (35), 31043-31054, 2011
1432011
α4β2 nicotinic acetylcholine receptors: relationships between subunit stoichiometry and function at the single channel level
S Mazzaferro, I Bermudez, SM Sine
Journal of Biological Chemistry 292 (7), 2729-2740, 2017
522017
Non-equivalent ligand selectivity of agonist sites in (α4β2) 2α4 nicotinic acetylcholine receptors: a key determinant of agonist efficacy
S Mazzaferro, F Gasparri, K New, C Alcaino, M Faundez, PI Vasquez, ...
Journal of Biological Chemistry 289 (31), 21795-21806, 2014
452014
The additional ACh binding site at the α4(+)/α4(−) interface of the (α4β2)2α4 nicotinic ACh receptor contributes to desensitization
N Benallegue, S Mazzaferro, C Alcaino, I Bermudez
British journal of pharmacology 170 (2), 304-316, 2013
352013
Role of the cys loop and transmembrane domain in the allosteric modulation of α4β2 nicotinic acetylcholine receptors
C Alcaino, M Musgaard, T Minguez, S Mazzaferro, M Faundez, ...
Journal of Biological Chemistry 292 (2), 551-562, 2017
312017
Additional acetylcholine (ACh) binding site at a4/a4 interface of (a4b2) 2a4 nicotinic receptor influences agonist sensitivity
S Mazzaferro, N Benallegue, A Carbone, F Gasparri, R Vijayan, ...
J Biol Chem 286, 31043-31054, 2011
232011
Potentiation of a neuronal nicotinic receptor via pseudo-agonist site
S Mazzaferro, I Bermudez, SM Sine
Cellular and molecular life sciences 76, 1151-1167, 2019
202019
NACHO and 14-3-3 promote expression of distinct subunit stoichiometries of the α4β2 acetylcholine receptor
S Mazzaferro, ST Whiteman, C Alcaino, A Beyder, SM Sine
Cellular and Molecular Life Sciences 78, 1565-1575, 2021
152021
Allosteric modulators of α4β2 nicotinic acetylcholine receptors: a new direction for antidepressant drug discovery
E Mantione, S Micheloni, C Alcaino, K New, S Mazzaferro, I Bermudez
Future Medicinal Chemistry 4 (17), 2217-2230, 2012
142012
Structural basis for α-bungarotoxin insensitivity of neuronal nicotinic acetylcholine receptors
SM Sine, JR Strikwerda, S Mazzaferro
Neuropharmacology 160, 107660, 2019
92019
Stoichiometry‐selective modulation of α4β2 nicotinic ACh receptors by divalent cations
S Mazzaferro, JR Strikwerda, SM Sine
British Journal of Pharmacology 179 (7), 1353-1370, 2022
62022
The additional acetylcholine binding site at the α4 (+)/α4 (−) interface of the (α4β2) 2α4 nicotinic acetylcholine receptor contributes to desensitisation
N Benallegue, S Mazzaferro, C Alcaino, I Bermudez
Br J Pharmacol 170, 304-316, 2013
62013
The fifth subunit of the (α4β2)2β2 nicotinic ACh receptor modulates maximal ACh responses
K New, SG Del Villar, S Mazzaferro, C Alcaino, I Bermudez
British Journal of Pharmacology 175 (11), 1822-1837, 2018
52018
Genetic Variant in Nicotinic Receptor α4-Subunit Causes Sleep-Related Hyperkinetic Epilepsy via Increased Channel Opening
SMS Simone Mazzaferro, Deborah J. Msekela, Edward C. Cooper, Atul Maheshwari
Int. J. Mol. Sci. 2022, 23(20), 12124; https://doi.org/10.3390/ijms232012124 …, 2022
4*2022
Differentiation, Transcriptomic Profiling, and Calcium Imaging of Human Hypothalamic Neurons
HJC Chen, S Mazzaferro, T Tian, I Mali, FT Merkle
Current protocols 3 (6), e786, 2023
32023
An analogue of the Prolactin Releasing Peptide reduces obesity and promotes adult neurogenesis
SKM Jörgensen, A Karnošová, S Mazzaferro, O Rowley, HJC Chen, ...
EMBO reports 25 (1), 351-377, 2024
12024
Profiling human hypothalamic neurons reveals a candidate combination drug therapy for weight loss
HJC Chen, A Yang, S Mazzaferro, I Mali, O Cahn, K Kentistou, C Rowley, ...
bioRxiv, 2023.07. 18.549357, 2023
12023
Structural bases for stoichiometry‐selective calcium potentiation of a neuronal nicotinic receptor
S Mazzaferro, G Kang, K Natarajan, RE Hibbs, SM Sine
British Journal of Pharmacology, 2024
2024
GLP1R agonists activate human POMC neurons
S Mazzaferro, HJC Chen, O Cahn, A Yang, D Shepilov, J Chen, C Alcaino, ...
bioRxiv, 2024.04. 02.587825, 2024
2024
THE FIFTH SUBUNIT MODULATES THE FUNCTION OF CANONICAL AGONIST SITES IN alpha 4 beta 2 NICOTINIC RECEPTORS
GS del Villar, K New, S Mazzaferro, S Bermudez
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 121, 47-47, 2017
2017
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