Kostantin Dobrenis
Kostantin Dobrenis
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Absence of colony stimulation factor-1 receptor results in loss of microglia, disrupted brain development and olfactory deficits
B Erblich, L Zhu, AM Etgen, K Dobrenis, JW Pollard
PloS one 6 (10), e26317, 2011
Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression
CD Davidson, NF Ali, MC Micsenyi, G Stephney, S Renault, K Dobrenis, ...
PloS one 4 (9), e6951, 2009
Microglial stimulation of glioblastoma invasion involves epidermal growth factor receptor (EGFR) and colony stimulating factor 1 receptor (CSF-1R) signaling
SJ Coniglio, E Eugenin, K Dobrenis, ER Stanley, BL West, MH Symons, ...
Molecular medicine 18, 519-527, 2012
Neurons in Niemann-Pick disease type C accumulate gangliosides as well as unesterified cholesterol and undergo dendritic and axonal alterations
M Zervas, K Dobrenis, SU Walkley
Journal of Neuropathology & Experimental Neurology 60 (1), 49-64, 2001
Differential subcellular localization of cholesterol, gangliosides, and glycosaminoglycans in murine models of mucopolysaccharide storage disorders
R McGlynn, K Dobrenis, SU Walkley
Journal of Comparative Neurology 480 (4), 415-426, 2004
Bone marrow transplantation corrects the enzyme defect in neurons of the central nervous system in a lysosomal storage disease.
SU Walkley, MA Thrall, K Dobrenis, M Huang, PA March, DA Siegel, ...
Proceedings of the National Academy of Sciences 91 (8), 2970-2974, 1994
A mouse model for mucopolysaccharidosis type III A (Sanfilippo syndrome)
M Bhaumik, VJ Muller, T Rozaklis, J Linda, K Dobrenis, R Bhattacharyya, ...
Glycobiology 9 (12), 1389-1396, 1999
Neuronal accumulation of glucosylceramide in a mouse model of neuronopathic Gaucher disease leads to neurodegeneration
T Farfel-Becker, EB Vitner, SL Kelly, JR Bame, J Duan, V Shinder, ...
Human molecular genetics 23 (4), 843-854, 2014
Human and mouse microglia express connexin36, and functional gap junctions are formed between rodent microglia and neurons
K Dobrenis, HY Chang, MH Pina‐Benabou, A Woodroffe, SC Lee, ...
Journal of neuroscience research 82 (3), 306-315, 2005
Macroautophagy is defective in mucolipin-1-deficient mouse neurons
C Curcio-Morelli, FA Charles, MC Micsenyi, Y Cao, B Venugopal, ...
Neurobiology of disease 40 (2), 370-377, 2010
Macroautophagy is defective in mucolipin-1-deficient mouse neurons
C Curcio-Morelli, FA Charles, MC Micsenyi, Y Cao, B Venugopal, ...
Neurobiology of disease 40 (2), 370-377, 2010
Neuropathology of the Mcoln1−/− Knockout Mouse Model of Mucolipidosis Type IV
MC Micsenyi, K Dobrenis, G Stephney, J Pickel, MT Vanier, ...
Journal of Neuropathology & Experimental Neurology 68 (2), 125-135, 2009
Efficacy and ototoxicity of different cyclodextrins in Niemann–Pick C disease
CD Davidson, YI Fishman, I Puskás, J Szemán, T Sohajda, LA McCauliff, ...
Annals of Clinical and Translational Neurology 3 (5), 366-380, 2016
Microglia in cell culture and in transplantation therapy for central nervous system disease
K Dobrenis
Methods 16 (3), 320-344, 1998
Protein transduction of Rab9 in Niemann‐Pick C cells reduces cholesterol storage
K Narita, A Choudhury, K Dobrenis, DK Sharma, EL Holicky, DL Marks, ...
The FASEB journal 19 (11), 1558-1560, 2005
X-linked Angelman-like syndrome caused by Slc9a6 knockout in mice exhibits evidence of endosomal–lysosomal dysfunction
P Strĝmme, K Dobrenis, RV Sillitoe, M Gulinello, NF Ali, C Davidson, ...
Brain 134 (11), 3369-3383, 2011
Neuronal lysosomal enzyme replacement using fragment C of tetanus toxin.
K Dobrenis, A Joseph, MC Rattazzi
Proceedings of the National Academy of Sciences 89 (6), 2297-2301, 1992
Occurrence of the opiate alkaloid-selective μ3 receptor in mammalian microglia, astrocytes and Kupffer cells
K Dobrenis, MH Makman, GB Stefano
Brain research 686 (2), 239-248, 1995
Granulocyte colony‐stimulating factor off‐target effect on nerve outgrowth promotes prostate cancer development
K Dobrenis, LR Gauthier, V Barroca, C Magnon
International journal of cancer 136 (4), 982-988, 2015
Lysosomal membrane permeability stimulates protein aggregate formation in neurons of a lysosomal disease
MC Micsenyi, J Sikora, G Stephney, K Dobrenis, SU Walkley
Journal of Neuroscience 33 (26), 10815-10827, 2013
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