ikbel achour
Tytuł
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Single-domain antibodies recognize selectively small oligomeric forms of amyloid β, prevent Aβ-induced neurotoxicity and inhibit fibril formation
P Lafaye, I Achour, P England, C Duyckaerts, F Rougeon
Molecular immunology 46 (4), 695-704, 2009
1032009
Tetrameric and homodimeric camelid IgGs originate from the same IgH locus
I Achour, P Cavelier, M Tichit, C Bouchier, P Lafaye, F Rougeon
The journal of immunology 181 (3), 2001-2009, 2008
752008
The discriminatory cost of ICD-10-CM transition between clinical specialties: metrics, case study, and mitigating tools
AD Boyd, JJ Li, MD Burton, M Jonen, V Gardeux, I Achour, RQ Luo, ...
Journal of the American Medical Informatics Association 20 (4), 708-717, 2013
512013
Network models of genome-wide association studies uncover the topological centrality of protein interactions in complex diseases
Y Lee, H Li, J Li, E Rebman, I Achour, KE Regan, ER Gamazon, JL Chen, ...
Journal of the American Medical Informatics Association, 2013
512013
Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform
A Klarenbeek, KE Mazouari, A Desmyter, C Blanchetot, A Hultberg, ...
MAbs 7 (4), 693-706, 2015
432015
Flexible ordering of antibody class switch and V(D)J joining during B-cell ontogeny
S Kumar, R Wuerffel, I Achour, B Lajoie, R Sen, J Dekker, AJ Feeney, ...
412013
‘N-of-1-pathways’ unveils personal deregulated mechanisms from a single pair of RNA-Seq samples: towards precision medicine
V Gardeux, I Achour, J Li, M Maienschein-Cline, H Li, L Pesce, ...
Journal of the American Medical Informatics Association 21 (6), 1015-1025, 2014
372014
Three dimensional architecture of the Igh locus facilitates class switch recombination
AL Kenter, S Feldman, R Wuerffel, I Achour, L Wang, S Kumar
Annals of the New York Academy of Sciences 1267 (1), 86, 2012
362012
Projection system with integrated optical device
M Peterson, J Gohman
US Patent 6,672,724, 2004
312004
hMSH2 expression is driven by AP1‐dependent regulation through phorbol‐ester exposure
O Humbert, I Achour, D Lautier, G Laurent, B Salles
Nucleic acids research 31 (19), 5627-5634, 2003
282003
Dynamic changes of RNA-sequencing expression for precision medicine: N-of-1-pathways Mahalanobis distance within pathways of single subjects predicts breast cancer survival
AG Schissler, V Gardeux, Q Li, I Achour, H Li, WW Piegorsch, YA Lussier
Bioinformatics 31 (12), i293-i302, 2015
242015
N-of-1-pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes
Q Li, AG Schissler, V Gardeux, I Achour, C Kenost, J Berghout, H Li, ...
BMC Medical Genomics 10 (1), 5-16, 2017
222017
A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbations
V Gardeux, J Berghout, I Achour, AG Schissler, Q Li, C Kenost, J Li, ...
Journal of the American Medical Informatics Association 24 (6), 1116-1126, 2017
212017
53BP1 contributes to Igh locus chromatin topology during class switch recombination
S Feldman, R Wuerffel, I Achour, L Wang, PB Carpenter, AL Kenter
The Journal of Immunology 198 (6), 2434-2444, 2017
202017
Constraints Contributed by Chromatin Looping Limit Recombination Targeting during Immunoglobulin Class Switch Recombination.
KAL Feldman S, Achour I, Wuerffel R, Kumar S, Gerasimova T, Sen R
Journal of Immunology, 2015
19*2015
Concordance of deregulated mechanisms unveiled in underpowered experiments: PTBP1 knockdown case study
V Gardeux, AD Arslan, I Achour, TT Ho, WT Beck, YA Lussier
BMC medical genomics 7 (1), 1-13, 2014
192014
Integrative genomics analyses unveil downstream biological effectors of disease-specific polymorphisms buried in intergenic regions
H Li, I Achour, L Bastarache, J Berghout, V Gardeux, J Li, Y Lee, L Pesce, ...
NPJ genomic medicine 1 (1), 1-12, 2016
172016
kMEn: Analyzing noisy and bidirectional transcriptional pathway responses in single subjects
Q Li, AG Schissler, V Gardeux, J Berghout, I Achour, C Kenost, H Li, ...
Journal of biomedical informatics 66, 32-41, 2017
152017
Anti-PD-1 monoclonal antibody MEDI0680 in a phase I study of patients with advanced solid malignancies
A Naing, J Infante, S Goel, H Burris, C Black, S Marshall, I Achour, ...
Journal for immunotherapy of cancer 7 (1), 1-15, 2019
122019
Analysis of aggregated cell–cell statistical distances within pathways unveils therapeutic-resistance mechanisms in circulating tumor cells
AG Schissler, Q Li, JL Chen, C Kenost, I Achour, DD Billheimer, H Li, ...
Bioinformatics 32 (12), i80-i89, 2016
112016
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