Nicholas P Restifo, MD
Nicholas P Restifo, MD
Cellular Immunotherapy Explorer
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Cancer regression in patients after transfer of genetically engineered lymphocytes
RA Morgan, ME Dudley, JR Wunderlich, MS Hughes, JC Yang, ...
Science 314 (5796), 126-129, 2006
Cancer immunotherapy: moving beyond current vaccines
SA Rosenberg, JC Yang, NP Restifo
Nature medicine 10 (9), 909-915, 2004
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
ME Dudley, JR Wunderlich, PF Robbins, JC Yang, P Hwu, ...
Science 298 (5594), 850-854, 2002
Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy
SA Rosenberg, JC Yang, RM Sherry, US Kammula, MS Hughes, ...
Clinical cancer research 17 (13), 4550-4557, 2011
Adoptive cell transfer as personalized immunotherapy for human cancer
SA Rosenberg, NP Restifo
Science 348 (6230), 62-68, 2015
Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma
SA Rosenberg, JC Yang, DJ Schwartzentruber, P Hwu, FM Marincola, ...
Nature medicine 4 (3), 321-327, 1998
Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
ME Dudley, JR Wunderlich, JC Yang, RM Sherry, SL Topalian, NP Restifo, ...
Journal of clinical oncology: official journal of the American Society of …, 2005
Adoptive cell transfer: a clinical path to effective cancer immunotherapy
SA Rosenberg, NP Restifo, JC Yang, RA Morgan, ME Dudley
Nature Reviews Cancer 8 (4), 299-308, 2008
A human memory T cell subset with stem cell–like properties
L Gattinoni, E Lugli, Y Ji, Z Pos, CM Paulos, MF Quigley, JR Almeida, ...
Nature medicine 17 (10), 1290-1297, 2011
Adoptive immunotherapy for cancer: harnessing the T cell response
NP Restifo, ME Dudley, SA Rosenberg
Nature Reviews Immunology 12 (4), 269-281, 2012
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
GQ Phan, JC Yang, RM Sherry, P Hwu, SL Topalian, ...
Proceedings of the National Academy of Sciences 100 (14), 8372-8377, 2003
Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1
PF Robbins, RA Morgan, SA Feldman, JC Yang, RM Sherry, ME Dudley, ...
Journal of Clinical Oncology 29 (7), 917, 2011
Adoptive immunotherapy for cancer: building on success
L Gattinoni, DJ Powell Jr, SA Rosenberg, NP Restifo
Nature Reviews Immunology 6 (5), 383-393, 2006
Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
LA Johnson, RA Morgan, ME Dudley, L Cassard, JC Yang, MS Hughes, ...
Blood, The Journal of the American Society of Hematology 114 (3), 535-546, 2009
Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens
ME Dudley, JC Yang, R Sherry, MS Hughes, R Royal, U Kammula, ...
Journal of Clinical Oncology 26 (32), 5233, 2008
Natural selection of tumor variants in the generation of “tumor escape” phenotypes
HT Khong, NP Restifo
Nature immunology 3 (11), 999-1005, 2002
Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy
RA Morgan, N Chinnasamy, D Abate-Daga, A Gros, PF Robbins, Z Zheng, ...
Journal of immunotherapy 36 (2), 133-151, 2013
Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells
L Gattinoni, SE Finkelstein, CA Klebanoff, PA Antony, DC Palmer, ...
The Journal of experimental medicine 202 (7), 907-912, 2005
T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis
MR Parkhurst, JC Yang, RC Langan, ME Dudley, DAN Nathan, ...
Molecular Therapy 19 (3), 620-626, 2011
Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells
CA Klebanoff, L Gattinoni, P Torabi-Parizi, K Kerstann, AR Cardones, ...
Proceedings of the national academy of sciences 102 (27), 9571-9576, 2005
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