Nicholas P Restifo, MD
Nicholas P Restifo, MD
Cellular Immunotherapy Explorer
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Cancer regression in patients after transfer of genetically engineered lymphocytes
RA Morgan, ME Dudley, JR Wunderlich, MS Hughes, JC Yang, ...
Science 314 (5796), 126-129, 2006
Cancer immunotherapy: moving beyond current vaccines
SA Rosenberg, JC Yang, NP Restifo
Nature medicine 10 (9), 909-915, 2004
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
ME Dudley, JR Wunderlich, PF Robbins, JC Yang, P Hwu, ...
Science 298 (5594), 850-854, 2002
Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapycomplete regressions in melanoma
SA Rosenberg, JC Yang, RM Sherry, US Kammula, MS Hughes, ...
Clinical cancer research 17 (13), 4550-4557, 2011
Adoptive cell transfer as personalized immunotherapy for human cancer
SA Rosenberg, NP Restifo
Science 348 (6230), 62-68, 2015
Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma
SA Rosenberg, JC Yang, DJ Schwartzentruber, P Hwu, FM Marincola, ...
Nature medicine 4 (3), 321-327, 1998
Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
ME Dudley, JR Wunderlich, JC Yang, RM Sherry, SL Topalian, NP Restifo, ...
Journal of clinical oncology: official journal of the American Society of …, 2005
Adoptive cell transfer: a clinical path to effective cancer immunotherapy
SA Rosenberg, NP Restifo, JC Yang, RA Morgan, ME Dudley
Nature Reviews Cancer 8 (4), 299-308, 2008
Adoptive immunotherapy for cancer: harnessing the T cell response
NP Restifo, ME Dudley, SA Rosenberg
Nature Reviews Immunology 12 (4), 269-281, 2012
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
GQ Phan, JC Yang, RM Sherry, P Hwu, SL Topalian, ...
Proceedings of the National Academy of Sciences 100 (14), 8372-8377, 2003
A human memory T cell subset with stem cell–like properties
L Gattinoni, E Lugli, Y Ji, Z Pos, CM Paulos, MF Quigley, JR Almeida, ...
Nature medicine 17 (10), 1290-1297, 2011
Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1
PF Robbins, RA Morgan, SA Feldman, JC Yang, RM Sherry, ME Dudley, ...
Journal of Clinical Oncology 29 (7), 917, 2011
Adoptive immunotherapy for cancer: building on success
L Gattinoni, DJ Powell Jr, SA Rosenberg, NP Restifo
Nature Reviews Immunology 6 (5), 383-393, 2006
Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
LA Johnson, RA Morgan, ME Dudley, L Cassard, JC Yang, MS Hughes, ...
Blood, The Journal of the American Society of Hematology 114 (3), 535-546, 2009
Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens
ME Dudley, JC Yang, R Sherry, MS Hughes, R Royal, U Kammula, ...
Journal of Clinical Oncology 26 (32), 5233, 2008
Natural selection of tumor variants in the generation of “tumor escape” phenotypes
HT Khong, NP Restifo
Nature immunology 3 (11), 999-1005, 2002
Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy
RA Morgan, N Chinnasamy, D Abate-Daga, A Gros, PF Robbins, Z Zheng, ...
Journal of immunotherapy 36 (2), 133-151, 2013
Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells
L Gattinoni, SE Finkelstein, CA Klebanoff, PA Antony, DC Palmer, ...
The Journal of experimental medicine 202 (7), 907-912, 2005
Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells
L Gattinoni, CA Klebanoff, DC Palmer, C Wrzesinski, K Kerstann, Z Yu, ...
The Journal of clinical investigation 115 (6), 1616-1626, 2005
Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti–cytotoxic T-lymphocyte antigen-4
P Attia, GQ Phan, AV Maker, MR Robinson, MM Quezado, JC Yang, ...
Journal of clinical oncology: official journal of the American Society of …, 2005
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