| The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain JM Lamar, P Stern, H Liu, JW Schindler, ZG Jiang, RO Hynes Proceedings of the National Academy of Sciences 109 (37), E2441-E2450, 2012 | 649 | 2012 |
| Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters A Naba, KR Clauser, JM Lamar, SA Carr, RO Hynes elife 3, e01308, 2014 | 427 | 2014 |
| A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis NE Reticker-Flynn, DFB Malta, MM Winslow, JM Lamar, MJ Xu, ... Nature communications 3 (1), 1122, 2012 | 217 | 2012 |
| Tumor cell–driven extracellular matrix remodeling drives haptotaxis during metastatic progression MJ Oudin, O Jonas, T Kosciuk, LC Broye, BC Guido, J Wyckoff, ... Cancer discovery 6 (5), 516-531, 2016 | 205 | 2016 |
| KLF8 promotes human breast cancer cell invasion and metastasis by transcriptional activation of MMP9 X Wang, H Lu, AM Urvalek, T Li, L Yu, J Lamar, CM DiPersio, PJ Feustel, ... Oncogene 30 (16), 1901-1911, 2011 | 190 | 2011 |
| α3β1 integrin promotes keratinocyte cell survival through activation of a MEK/ERK signaling pathway A Manohar, SG Shome, J Lamar, L Stirling, V Iyer, K Pumiglia, ... Journal of cell science 117 (18), 4043-4054, 2004 | 158 | 2004 |
| YAP/TAZ activation as a target for treating metastatic cancer JSA Warren, Y Xiao, JM Lamar Cancers 10 (4), 115, 2018 | 154 | 2018 |
| SRC tyrosine kinase activates the YAP/TAZ axis and thereby drives tumor growth and metastasis JM Lamar, Y Xiao, E Norton, ZG Jiang, GM Gerhard, S Kooner, ... Journal of Biological Chemistry 294 (7), 2302-2317, 2019 | 151 | 2019 |
| Elucidation of the roles of tumor integrin β1 in the extravasation stage of the metastasis cascade MB Chen, JM Lamar, R Li, RO Hynes, RD Kamm Cancer research 76 (9), 2513-2524, 2016 | 150 | 2016 |
| Proteomic profiling of the ECM of xenograft breast cancer metastases in different organs reveals distinct metastatic niches JD Hebert, SA Myers, A Naba, G Abbruzzese, JM Lamar, SA Carr, ... Cancer research 80 (7), 1475-1485, 2020 | 86 | 2020 |
| Endothelial α3β1-integrin represses pathological angiogenesis and sustains endothelial-VEGF RG Da Silva, B Tavora, SD Robinson, LE Reynolds, C Szekeres, J Lamar, ... The American journal of pathology 177 (3), 1534-1548, 2010 | 77 | 2010 |
| Integrin α3β1 potentiates TGFβ-mediated induction of MMP-9 in immortalized keratinocytes JM Lamar, V Iyer, CM DiPersio Journal of investigative dermatology 128 (3), 575-586, 2008 | 68 | 2008 |
| RUNX1 and RUNX3 protect against YAP-mediated EMT, stem-ness and shorter survival outcomes in breast cancer M Kulkarni, TZ Tan, NBS Sulaiman, JM Lamar, P Bansal, J Cui, Y Qiao, ... Oncotarget 9 (18), 14175, 2018 | 66 | 2018 |
| An immortalization-dependent switch in integrin function up-regulates MMP-9 to enhance tumor cell invasion JM Lamar, KM Pumiglia, CM DiPersio Cancer research 68 (18), 7371-7379, 2008 | 66 | 2008 |
| WWTR1 (TAZ)-CAMTA1 gene fusion is sufficient to dysregulate YAP/TAZ signaling and drive epithelioid hemangioendothelioma tumorigenesis CN Seavey, AV Pobbati, A Hallett, S Ma, JP Reynolds, R Kanai, JM Lamar, ... Genes & development 35 (7-8), 512-527, 2021 | 40 | 2021 |
| MEF2 (myocyte enhancer factor 2) is essential for endothelial homeostasis and the atheroprotective gene expression program YW Lu, N Martino, BD Gerlach, JM Lamar, PA Vincent, AP Adam, ... Arteriosclerosis, thrombosis, and vascular biology 41 (3), 1105-1123, 2021 | 35 | 2021 |
| Epithelioid hemangioendothelioma as a model of YAP/TAZ-driven cancer: insights from a rare fusion sarcoma JM Lamar, V Motilal Nehru, G Weinberg Cancers 10 (7), 229, 2018 | 35 | 2018 |
| Nephronectin is correlated with poor prognosis in breast cancer and promotes metastasis via its integrin-binding motifs TS Steigedal, J Toraskar, RP Redvers, M Valla, SN Magnussen, AM Bofin, ... Neoplasia 20 (4), 387-400, 2018 | 34 | 2018 |
| Complex Rab4-mediated regulation of endosomal size and EGFR activation K Tubbesing, J Ward, R Abini-Agbomson, A Malhotra, A Rudkouskaya, ... Molecular Cancer Research 18 (5), 757-773, 2020 | 24 | 2020 |
| Radiation-induced macrophage senescence impairs resolution programs and drives cardiovascular inflammation S Sadhu, C Decker, BE Sansbury, M Marinello, A Seyfried, J Howard, ... The Journal of Immunology 207 (7), 1812-1823, 2021 | 23 | 2021 |
Kevin PumigliaProfessor of Regenerative and Cancer Cell BilogyVerified email at mail.amc.edu
