Liquid biopsies come of age: towards implementation of circulating tumour DNA JCM Wan, C Massie, J Garcia-Corbacho, F Mouliere, JD Brenton, ... Nature Reviews Cancer 17 (4), 223-238, 2017 | 2396 | 2017 |
Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2 J Nangalia, CE Massie, EJ Baxter, FL Nice, G Gundem, DC Wedge, ... New England Journal of Medicine 369 (25), 2391-2405, 2013 | 2219 | 2013 |
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1935* | 2020 |
Somatic SF3B1 Mutation in Myelodysplasia with Ring Sideroblasts E Papaemmanuil, M Cazzola, J Boultwood, L Malcovati, P Vyas, D Bowen, ... New England Journal of Medicine 365 (15), 1384-1395, 2011 | 1476 | 2011 |
Enhanced detection of circulating tumor DNA by fragment size analysis F Mouliere, D Chandrananda, AM Piskorz, EK Moore, J Morris, ... Science translational medicine 10 (466), eaat4921, 2018 | 909 | 2018 |
The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis CE Massie, A Lynch, A Ramos‐Montoya, J Boren, R Stark, L Fazli, ... The EMBO journal 30 (13), 2719-2733, 2011 | 721 | 2011 |
Effect of mutation order on myeloproliferative neoplasms CA Ortmann, DG Kent, J Nangalia, Y Silber, DC Wedge, J Grinfeld, ... New England Journal of Medicine 372 (7), 601-612, 2015 | 627 | 2015 |
Classification and personalized prognosis in myeloproliferative neoplasms J Grinfeld, J Nangalia, EJ Baxter, DC Wedge, N Angelopoulos, R Cantrill, ... New England Journal of Medicine 379 (15), 1416-1430, 2018 | 616 | 2018 |
Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue CS Cooper, R Eeles, DC Wedge, P Van Loo, G Gundem, LB Alexandrov, ... Nature genetics 47 (4), 367-372, 2015 | 489 | 2015 |
The androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man NL Sharma, CE Massie, A Ramos-Montoya, V Zecchini, HE Scott, ... Cancer cell 23 (1), 35-47, 2013 | 439 | 2013 |
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer YS Ju, LB Alexandrov, M Gerstung, I Martincorena, S Nik-Zainal, ... elife 3, e02935, 2014 | 425 | 2014 |
New androgen receptor genomic targets show an interaction with the ETS1 transcription factor CE Massie, B Adryan, NL Barbosa‐Morais, AG Lynch, MG Tran, DE Neal, ... EMBO reports 8 (9), 871-878, 2007 | 303 | 2007 |
Cooperative interaction between retinoic acid receptor-α and estrogen receptor in breast cancer CS Ross-Innes, R Stark, KA Holmes, D Schmidt, C Spyrou, R Russell, ... Genes & development 24 (2), 171-182, 2010 | 286 | 2010 |
Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer M Asim, F Tarish, HI Zecchini, K Sanjiv, E Gelali, CE Massie, A Baridi, ... Nature communications 8 (1), 374, 2017 | 284 | 2017 |
The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel AA Ahmed, AD Mills, AEK Ibrahim, J Temple, C Blenkiron, M Vias, ... Cancer cell 12 (6), 514-527, 2007 | 249 | 2007 |
Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets DC Wedge, G Gundem, T Mitchell, DJ Woodcock, I Martincorena, M Ghori, ... Nature genetics 50 (5), 682-692, 2018 | 244 | 2018 |
OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer GC Sellar, KP Watt, GJ Rabiasz, EA Stronach, L Li, EP Miller, CE Massie, ... Nature genetics 34 (3), 337-343, 2003 | 242 | 2003 |
Inactivating CUX1 mutations promote tumorigenesis CC Wong, I Martincorena, AG Rust, M Rashid, C Alifrangis, ... Nature genetics 46 (1), 33-38, 2014 | 170 | 2014 |
ctDNA monitoring using patient-specific sequencing and integration of variant reads JCM Wan, K Heider, D Gale, S Murphy, E Fisher, F Mouliere, ... Science translational medicine 12 (548), eaaz8084, 2020 | 163 | 2020 |
The importance of DNA methylation in prostate cancer development CE Massie, IG Mills, AG Lynch The Journal of steroid biochemistry and molecular biology 166, 1-15, 2017 | 160 | 2017 |