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Aaron Debono
Aaron Debono
Verified email at monash.edu
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Cited by
Year
Progress toward the development of noscapine and derivatives as anticancer agents
A DeBono, B Capuano, PJ Scammells
Journal of medicinal chemistry 58 (15), 5699-5727, 2015
972015
Synthesis and Biological Evaluation of N‐Substituted Noscapine Analogues
AJ DeBono, JH Xie, S Ventura, CW Pouton, B Capuano, PJ Scammells
ChemMedChem 7 (12), 2122-2133, 2012
542012
8‐Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase
ML Dennis, MD Lee, JR Harjani, M Ahmed, AJ DeBono, NP Pitcher, ...
Chemistry–A European Journal 24 (8), 1922-1930, 2018
422018
The synthesis and biological evaluation of multifunctionalised derivatives of noscapine as cytotoxic agents
AJ DeBono, SJ Mistry, J Xie, D Muthiah, J Phillips, S Ventura, ...
ChemMedChem 9 (2), 399-410, 2014
392014
Identification of novel antivirals inhibiting recognition of Venezuelan equine encephalitis virus capsid protein by the Importin α/β1 heterodimer through high-throughput screening
DR Thomas, L Lundberg, C Pinkham, S Shechter, A DeBono, J Baell, ...
Antiviral research 151, 8-19, 2018
292018
Novel inhibitors targeting Venezuelan equine encephalitis virus capsid protein identified using In Silico Structure-Based-Drug-Design
S Shechter, DR Thomas, L Lundberg, C Pinkham, SC Lin, KM Wagstaff, ...
Scientific Reports 7 (1), 17705, 2017
272017
Substituted Pyridazin-3(2H)-ones as Highly Potent and Biased Formyl Peptide Receptor Agonists
GS Deora, CX Qin, EA Vecchio, AJ Debono, DL Priebbenow, RM Brady, ...
Journal of Medicinal Chemistry 62 (10), 5242-5248, 2019
192019
Overcoming P-glycoprotein–mediated drug resistance with noscapine derivatives
D Muthiah, GK Henshaw, AJ DeBono, B Capuano, PJ Scammells, ...
Drug Metabolism and Disposition 47 (2), 164-172, 2019
192019
Structure-based design and development of functionalized Mercaptoguanine derivatives as inhibitors of the folate biosynthesis pathway enzyme 6-hydroxymethyl-7, 8-dihydropterin …
ML Dennis, S Chhabra, ZC Wang, A Debono, O Dolezal, J Newman, ...
Journal of Medicinal Chemistry 57 (22), 9612-9626, 2014
192014
Negative allosteric modulators of the human calcium‐sensing receptor bind to overlapping and distinct sites within the 7‐transmembrane domain
TM Josephs, AN Keller, E Khajehali, A DeBono, CJ Langmead, ...
British journal of pharmacology 177 (8), 1917-1930, 2020
172020
Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli
ML Dennis, NP Pitcher, MD Lee, AJ DeBono, ZC Wang, JR Harjani, ...
Journal of Medicinal Chemistry 59 (11), 5248-5263, 2016
172016
Therapeutic opportunities of targeting allosteric binding sites on the calcium-sensing receptor
J Diao, A DeBono, TM Josephs, JE Bourke, B Capuano, KJ Gregory, ...
ACS Pharmacology & Translational Science 4 (2), 666-679, 2021
152021
Novel RU486 (mifepristone) analogues with increased activity against Venezuelan Equine Encephalitis Virus but reduced progesterone receptor antagonistic activity
A DeBono, DR Thomas, L Lundberg, C Pinkham, Y Cao, JD Graham, ...
Scientific reports 9 (1), 2634, 2019
152019
Correspondence: Reply to ‘Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury’
CX Qin, LT May, PM Sexton, AJ DeBono, JB Baell, A Christopoulos, ...
Nature Communications 9 (1), 530, 2018
82018
Development of AC265347‐Inspired Calcium‐Sensing Receptor Ago‐Positive Allosteric Modulators
LV Dinh, A DeBono, AN Keller, TM Josephs, KJ Gregory, K Leach, ...
ChemMedChem 16 (22), 3451-3462, 2021
22021
Reply to'Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury'
CX Qin, LT May, PM Sexton, AJ DeBono, JB Baell, A Christopoulos, ...
NATURE COMMUNICATIONS 9, 2018
2018
Novel inhibitors targeting Venezuelan equine encephalitis virus capsid protein identified using In Silico Structure-Based-Drug-Design (vol 7, 17705, 2017)
S Shechter, DR Thomas, L Lundberg, C Pinkham, SC Lin, KM Wagstaff, ...
Scientific Reports, 2018
2018
The structure activity relationships of noscapine related compounds and their pharmacological evaluation
AJ DeBono
Monash University, 2014
2014
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