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Mate Gyimesi
Mate Gyimesi
ELTE Eötvös Loránd University
Zweryfikowany adres z ttk.elte.hu
Tytuł
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Targeting myosin by blebbistatin derivatives: optimization and pharmacological potential
AÁ Rauscher, M Gyimesi, M Kovács, A Málnási-Csizmadia
Trends in biochemical sciences 43 (9), 700-713, 2018
972018
From keys to bulldozers: expanding roles for winged helix domains in nucleic-acid-binding proteins
GM Harami, M Gyimesi, M Kovács
Trends in biochemical sciences 38 (7), 364-371, 2013
932013
Reversible movement of switch 1 loop of myosin determines actin interaction
B Kintses, M Gyimesi, DS Pearson, MA Geeves, W Zeng, CR Bagshaw, ...
The EMBO journal 26 (1), 265-274, 2007
722007
The mechanism of the reverse recovery step, phosphate release, and actin activation of Dictyostelium myosin II
M Gyimesi, B Kintses, A Bodor, A Perczel, S Fischer, CR Bagshaw, ...
Journal of biological chemistry 283 (13), 8153-8163, 2008
672008
Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke
B Takács, N Billington, M Gyimesi, B Kintses, A Málnási-Csizmadia, ...
Proceedings of the National Academy of Sciences 107 (15), 6799-6804, 2010
622010
Processive translocation mechanism of the human Bloom’s syndrome helicase along single-stranded DNA
M Gyimesi, K Sarlos, M Kovacs
Nucleic acids research 38 (13), 4404-4414, 2010
522010
Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state
M Špírek, J Mlčoušková, O Beláň, M Gyimesi, GM Harami, E Molnár, ...
Nucleic Acids Research 46 (8), 3967-3980, 2018
402018
Shuttling along DNA and directed processing of D-loops by RecQ helicase support quality control of homologous recombination
GM Harami, Y Seol, J In, V Ferencziová, M Martina, M Gyimesi, K Sarlós, ...
Proceedings of the National Academy of Sciences 114 (4), E466-E475, 2017
362017
RecQ helicase translocates along single-stranded DNA with a moderate processivity and tight mechanochemical coupling
K Sarlós, M Gyimesi, M Kovács
Proceedings of the National Academy of Sciences 109 (25), 9804-9809, 2012
352012
Complex activities of the human Bloom's syndrome helicase are encoded in a core region comprising the RecA and Zn-binding domains
M Gyimesi, GM Harami, K Sarlos, E Hazai, Z Bikadi, M Kovacs
Nucleic acids research 40 (9), 3952-3963, 2012
312012
Single residue variation in skeletal muscle myosin enables direct and selective drug targeting for spasticity and muscle stiffness
M Gyimesi, ÁI Horváth, D Túrós, SK Suthar, M Pénzes, C Kurdi, L Canon, ...
Cell 183 (2), 335-346. e13, 2020
272020
RecQ helicase triggers a binding mode change in the SSB–DNA complex to efficiently initiate DNA unwinding
M Mills, GM Harami, Y Seol, M Gyimesi, M Martina, ZJ Kovács, M Kovács, ...
Nucleic acids research 45 (20), 11878-11890, 2017
252017
Enzyme kinetics above denaturation temperature: a temperature-jump/stopped-flow apparatus
B Kintses, Z Simon, M Gyimesi, J Tóth, B Jelinek, C Niedetzky, M Kovács, ...
Biophysical journal 91 (12), 4605-4610, 2006
252006
kinetic characterization of the function of myosin loop 4 in the actin− myosin interaction
M Gyimesi, AK Tsaturyan, MSZ Kellermayer, A Málnási-Csizmadia
Biochemistry 47 (1), 283-291, 2008
242008
Myosin cleft closure by double electron–electron resonance and dipolar EPR
PG Fajer, M Gyimesi, A Malnasi-Csizmadia, CR Bagshaw, KI Sen, L Song
Journal of Physics: Condensed Matter 19 (28), 285208, 2007
212007
Functional adaptation of the switch-2 nucleotide sensor enables rapid processive translocation by myosin-5.
NT Nagy, T Sakamoto, B Takács, M Gyimesi, E Hazai, Z Bikádi, JR Sellers, ...
The FASEB Journal 24 (11), 4480, 2010
202010
Visualization of human Bloom's syndrome helicase molecules bound to homologous recombination intermediates
M Gyimesi, RH Pires, N Billington, ZS Kocsis, K Módos, MSZ Kellermayer, ...
The FASEB Journal 27 (12), 4954, 2013
182013
Streamlined determination of processive run length and mechanochemical coupling of nucleic acid motor activities
M Gyimesi, K Sarlós, I Derényi, M Kovács
Nucleic acids research 38 (7), e102-e102, 2010
172010
Direct myosin-2 inhibition enhances cerebral perfusion resulting in functional improvement after ischemic stroke
M Pénzes, D Túrós, D Máthé, K Szigeti, N Hegedűs, AÁ Rauscher, P Tóth, ...
Theranostics 10 (12), 5341, 2020
132020
Effect of allosteric inhibition of non-muscle myosin 2 on its intracellular diffusion
ÁI Horváth, M Gyimesi, BH Várkuti, M Képiró, G Szegvári, I Lőrincz, ...
Scientific Reports 10 (1), 13341, 2020
92020
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