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Maciej Gielnik
Maciej Gielnik
Department of Molecular Biology and Genetics, Aarhus University
Zweryfikowany adres z mbg.au.dk
Tytuł
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Cytowane przez
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Zn (II) binding causes interdomain changes in the structure and flexibility of the human prion protein
M Gielnik, M Taube, L Zhukova, I Zhukov, SKTS Wärmländer, Ž Svedružić, ...
Scientific reports 11 (1), 21703, 2021
102021
PrP (58–93) peptide from unstructured N-terminal domain of human prion protein forms amyloid-like fibrillar structures in the presence of Zn 2+ ions
M Gielnik, Z Pietralik, I Zhukov, A Szymańska, WM Kwiatek, M Kozak
RSC advances 9 (39), 22211-22219, 2019
92019
The engineered peptide construct NCAM1-Aβ inhibits fibrillization of the human prion protein (PrP)
M Gielnik, L Zhukova, I Zhukov, A Gräslund, M Kozak, SKTS Wärmländer
Acta Biochimica Polonica, https://doi.org/10.18388/abp.2020_5679, 2022
7*2022
Effect of posttranslational modifications on the structure and activity of FTO demethylase
M Marcinkowski, T Pilžys, D Garbicz, J Piwowarski, D Mielecki, ...
International journal of molecular sciences 22 (9), 4512, 2021
52021
Characterization of Uranyl (UO22+) Ion Binding to Amyloid Beta (Aβ) Peptides: Effects on Aβ Structure and Aggregation
E Berntsson, F Vosough, A Noormagi, K Padari, F Asplund, M Gielnik, ...
ACS Chemical Neuroscience 14 (15), 2618-2633, 2023
32023
Prion Protein Octarepeat Domain Forms Transient β-Sheet Structures upon Residue-Specific Binding to Cu (II) and Zn (II) Ions
M Gielnik, A Szymańska, X Dong, J Jarvet, ZM Svedruzic, A Graslund, ...
Biochemistry 62 (11), 1689-1705, 2023
22023
The prion protein octarepeat domain forms transient β-sheet structures upon residue-specific Cu (II) and Zn (II) binding
M Gielnik, A Szymańska, X Dong, J Jarvet, ŽM Svedružić, A Gräslund, ...
bioRxiv, 2021.12. 12.472308, 2021
12021
Design of functional intrinsically disordered proteins
A Garg, NS González-Foutel, MB Gielnik, M Kjaergaard
Protein Engineering, Design and Selection 37, gzae004, 2024
2024
Fałdowanie i agregacja ludzkiego białka prionowego: biofizyczne badania oddziaływań z jonami metali oraz konstruktem peptydowym NCAM1-Aβ
M Gielnik
2022
FTO DIOXYGENASE STRUCTURE AND ITS INTERACTORS-BIOPHYSICAL STUDIES.
M Marcinkowski, T Pilzys, D Garbicz, M Winiewska, A Maciejewska, ...
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 59, 95-95, 2018
2018
Fibrillation of N-Terminal Prion Protein Fragment in Presence of Zinc Ions
MB Gielnik, M Nowakowski, A Szymańska, IY Zhukov, WM Kwiatek, ...
Biophysical Journal 114 (3), 429a, 2018
2018
Conformational Dynamics of Human Prion Protein and Binding Sites of Zn Cations
M Gielnik, M Nowakowski, M Taube, I Zhukov, WM Kwiatek, DM Lesovoy, ...
Biophysical Journal 114 (3), 387a, 2018
2018
Selected applications of small-angle X-ray and neutron scattering (SAXS/SANS) in studies of complexes and flexible protein structures
M Kozak, M Taube, M Gielnik, Z Pietralik
Acta Biochimica Polonica 65 (S2), 2018
2018
Spectroscopic and SAXS Studies of Human Prion Protein Variants Complexed with Divalent Cations
M Kozak, M Gielnik, M Taube, I Zhukov
Biophysical Journal 112 (3), 190a, 2017
2017
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