Isabel Cardoso
Isabel Cardoso
IBMC- Instituto de Biologia Molecular e Celular
Zweryfikowany adres z ibmc.up.pt
Tytuł
Cytowane przez
Cytowane przez
Rok
Deposition of transthyretin in early stages of familial amyloidotic polyneuropathy: evidence for toxicity of nonfibrillar aggregates
MM Sousa, I Cardoso, R Fernandes, A Guimaraes, MJ Saraiva
The American journal of pathology 159 (6), 1993-2000, 2001
3632001
Tetramer dissociation and monomer partial unfolding precedes protofibril formation in amyloidogenic transthyretin variants
A Quintas, DC Vaz, I Cardoso, MJM Saraiva, RMM Brito
Journal of Biological Chemistry 276 (29), 27207-27213, 2001
3232001
Doxycycline disrupts transthyretin amyloid: evidence from studies in a FAP transgenic mice model
I Cardoso, MJ Saraiva
The FASEB Journal 20 (2), 234-239, 2006
1442006
Synergy of combined doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated biomarkers: studies in FAP mouse models
I Cardoso, D Martins, T Ribeiro, G Merlini, MJ Saraiva
Journal of translational medicine 8 (1), 74, 2010
1362010
Transthyretin binding to A-Beta peptide–impact on A-Beta fibrillogenesis and toxicity
R Costa, A Goncalves, MJ Saraiva, I Cardoso
FEBS letters 582 (6), 936-942, 2008
1282008
Transthyretin fibrillogenesis entails the assembly of monomers: a molecular model for in vitro assembled transthyretin amyloid-like fibrils
I Cardoso, CS Goldsbury, SA Müller, V Olivieri, S Wirtz, AM Damas, ...
Journal of molecular biology 317 (5), 683-695, 2002
1252002
4′‐iodo‐4′‐deoxydoxorubicin and tetracyclines disrupt transthyretin amyloid fibrils in vitro producing noncytotoxic species: screening for TTR fibril disrupters
I Cardoso, G Merlini, MJ Saraiva
The FASEB journal 17 (8), 803-809, 2003
1222003
Transthyretin protects against A-beta peptide toxicity by proteolytic cleavage of the peptide: a mechanism sensitive to the Kunitz protease inhibitor
R Costa, F Ferreira-da-Silva, MJ Saraiva, I Cardoso
PloS one 3 (8), e2899, 2008
1172008
Transthyretin and Alzheimer's disease: where in the brain?
JC Sousa, I Cardoso, F Marques, MJ Saraiva, JA Palha
Neurobiology of aging 28 (5), 713-718, 2007
1152007
Binding of epigallocatechin-3-gallate to transthyretin modulates its amyloidogenicity
N Ferreira, I Cardoso, MR Domingues, R Vitorino, M Bastos, G Bai, ...
FEBS letters 583 (22), 3569-3576, 2009
1122009
Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative
MR Almeida, B Macedo, I Cardoso, I Alves, G Valencia, G Arsequell, ...
Biochemical Journal 381 (2), 351-356, 2004
942004
Small transthyretin (TTR) ligands as possible therapeutic agents in TTR amyloidoses
MR Almeida, L Gales, AM Damas, I Cardoso, MJ Saraiva
Current Drug Targets-CNS & Neurological Disorders 4 (5), 587-596, 2005
672005
4′-Iodo-4′-deoxydoxorubicin disrupts the fibrillar structure of transthyretin amyloid
JA Palha, D Ballinari, N Amboldi, I Cardoso, R Fernandes, V Bellotti, ...
The American journal of pathology 156 (6), 1919-1925, 2000
632000
Activation of ERK1/2 MAP kinases in familial amyloidotic polyneuropathy
FA Monteiro, MM Sousa, I Cardoso, JB do Amaral, A Guimarães, ...
Journal of neurochemistry 97 (1), 151-161, 2006
572006
Testing the therapeutic potential of doxycycline in a Drosophila melanogaster model of Alzheimer disease
R Costa, E Speretta, DC Crowther, I Cardoso
Journal of Biological Chemistry 286 (48), 41647-41655, 2011
562011
Calcium ions promote superoxide dismutase 1 (SOD1) aggregation into non-fibrillar amyloid a link to toxic effects of calcium overload in amyotrophic lateral sclerosis (ALS)?
SS Leal, I Cardoso, JS Valentine, CM Gomes
Journal of Biological Chemistry 288 (35), 25219-25228, 2013
472013
Design and biological activity of β-sheet breaker peptide conjugates
S Rocha, I Cardoso, H Börner, MC Pereira, MJ Saraiva, M Coelho
Biochemical and biophysical research communications 380 (2), 397-401, 2009
452009
Controlling Amyloid‐β Peptide (1–42) Oligomerization and Toxicity by Fluorinated Nanoparticles
AM Saraiva, I Cardoso, MC Pereira, MAN Coelho, MJ Saraiva, ...
ChemBioChem 11 (13), 1905-1913, 2010
432010
Randomization of Amyloid‐β‐Peptide (1‐42) Conformation by Sulfonated and Sulfated Nanoparticles Reduces Aggregation and Cytotoxicity
AM Saraiva, I Cardoso, MJ Saraiva, K Tauer, MC Pereira, MAN Coelho, ...
Macromolecular bioscience 10 (10), 1152-1163, 2010
412010
Comparative in vitro and ex vivo activities of selected inhibitors of transthyretin aggregation: relevance in drug design
I Cardoso, MR Almeida, N Ferreira, G Arsequell, G Valencia, MJ Saraiva
Biochemical Journal 408 (1), 131-138, 2007
402007
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