| TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome RHJ Olsen, JF DiBerto, JG English, AM Glaudin, BE Krumm, ST Slocum, ... Nature chemical biology 16 (8), 841-849, 2020 | 408 | 2020 |
| Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys Y Nagai, N Miyakawa, H Takuwa, Y Hori, K Oyama, B Ji, M Takahashi, ... Nature neuroscience 23 (9), 1157-1167, 2020 | 286 | 2020 |
| Virtual discovery of melatonin receptor ligands to modulate circadian rhythms RM Stein, HJ Kang, JD McCorvy, GC Glatfelter, AJ Jones, T Che, ... Nature 579 (7800), 609-614, 2020 | 266 | 2020 |
| Structural basis of ligand recognition at the human MT1 melatonin receptor B Stauch, LC Johansson, JD McCorvy, N Patel, GW Han, XP Huang, ... Nature 569 (7755), 284-288, 2019 | 196 | 2019 |
| DREADD Agonist 21 Is an Effective Agonist for Muscarinic-Based DREADDs in Vitro and in Vivo KJ Thompson, E Khajehali, SJ Bradley, JS Navarrete, XP Huang, ... ACS Pharmacology & Translational Science 1 (1), 61-72, 2018 | 178 | 2018 |
| Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity AL Kaplan, DN Confair, K Kim, X Barros-Álvarez, RM Rodriguiz, Y Yang, ... Nature 610 (7932), 582-591, 2022 | 169 | 2022 |
| Structure, function and pharmacology of human itch GPCRs C Cao, HJ Kang, I Singh, H Chen, C Zhang, W Ye, BW Hayes, J Liu, ... Nature 600 (7887), 170-175, 2021 | 151 | 2021 |
| XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity LC Johansson, B Stauch, JD McCorvy, GW Han, N Patel, XP Huang, ... Nature 569 (7755), 289-292, 2019 | 145 | 2019 |
| Chemoenzymatic Total Synthesis and Structural Diversification of Tylactone-Based Macrolide Antibiotics through Late-Stage Polyketide Assembly, Tailoring, and C H Functionalization AN Lowell, MD DeMars, ST Slocum, F Yu, K Anand, JA Chemler, ... Journal of the American Chemical Society 139 (23), 7913-7920, 2017 | 87 | 2017 |
| The activities of drug inactive ingredients on biological targets J Pottel, D Armstrong, L Zou, A Fekete, XP Huang, H Torosyan, ... Science 369 (6502), 403-413, 2020 | 77 | 2020 |
| Structure-based design of bitopic ligands for the µ-opioid receptor A Faouzi, H Wang, SA Zaidi, JF DiBerto, T Che, Q Qu, MJ Robertson, ... Nature 613 (7945), 767-774, 2023 | 72 | 2023 |
| Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site R Uprety, T Che, SA Zaidi, SG Grinnell, BR Varga, A Faouzi, ST Slocum, ... Elife 10, e56519, 2021 | 58 | 2021 |
| Oxidative metabolism as a modulator of kratom’s biological actions S Chakraborty, R Uprety, ST Slocum, T Irie, V Le Rouzic, X Li, LL Wilson, ... Journal of medicinal chemistry 64 (22), 16553-16572, 2021 | 44 | 2021 |
| Molecular insights into psychedelic drug action ST Slocum, JF DiBerto, BL Roth Journal of neurochemistry 162 (1), 24-38, 2022 | 43 | 2022 |
| Neurotensin receptor allosterism revealed in complex with a biased allosteric modulator BE Krumm, JF DiBerto, RHJ Olsen, HJ Kang, ST Slocum, S Zhang, ... Biochemistry 62 (7), 1233-1248, 2023 | 31 | 2023 |
| Structure-Based Design of a Chemical Probe Set for the 5-HT5A Serotonin Receptor A Levit Kaplan, RT Strachan, JM Braz, V Craik, S Slocum, T Mangano, ... Journal of medicinal chemistry 65 (5), 4201-4217, 2022 | 30 | 2022 |
| Design, synthesis, and characterization of ogerin-based positive allosteric modulators for G protein-coupled receptor 68 (GPR68) X Yu, XP Huang, TP Kenakin, ST Slocum, X Chen, ML Martini, J Liu, J Jin Journal of medicinal chemistry 62 (16), 7557-7574, 2019 | 28 | 2019 |
| 5-HT2A SNPs Alter the Pharmacological Signaling of Potentially Therapeutic Psychedelics GP Schmitz, MK Jain, ST Slocum, BL Roth ACS Chemical Neuroscience 13 (16), 2386-2398, 2022 | 20 | 2022 |
| HypoRiPPAtlas as an Atlas of hypothetical natural products for mass spectrometry database search YY Lee, M Guler, DN Chigumba, S Wang, N Mittal, C Miller, ... Nature Communications 14 (1), 4219, 2023 | 10 | 2023 |
| Chemoenzymatic dissection of polyketide β-branching in the bryostatin pathway ST Slocum, AN Lowell, A Tripathi, VV Shende, JL Smith, DH Sherman Methods in enzymology 604, 207-236, 2018 | 8 | 2018 |
