Samuel Slocum
Samuel Slocum
Postdoctoral Associate, University of North Carolina
Verified email at
Cited by
Cited by
TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome
RHJ Olsen, JF DiBerto, JG English, AM Glaudin, BE Krumm, ST Slocum, ...
Nature chemical biology 16 (8), 841-849, 2020
Virtual discovery of melatonin receptor ligands to modulate circadian rhythms
RM Stein, HJ Kang, JD McCorvy, GC Glatfelter, AJ Jones, T Che, ...
Nature 579 (7800), 609-614, 2020
Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys
Y Nagai, N Miyakawa, H Takuwa, Y Hori, K Oyama, B Ji, M Takahashi, ...
Nature neuroscience 23 (9), 1157-1167, 2020
Structural basis of ligand recognition at the human MT1 melatonin receptor
B Stauch, LC Johansson, JD McCorvy, N Patel, GW Han, XP Huang, ...
Nature 569 (7755), 284-288, 2019
DREADD Agonist 21 Is an Effective Agonist for Muscarinic-Based DREADDs in Vitro and in Vivo
KJ Thompson, E Khajehali, SJ Bradley, JS Navarrete, XP Huang, ...
ACS Pharmacology & Translational Science 1 (1), 61-72, 2018
XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity
LC Johansson, B Stauch, JD McCorvy, GW Han, N Patel, XP Huang, ...
Nature 569 (7755), 289-292, 2019
Structure, function and pharmacology of human itch GPCRs
C Cao, HJ Kang, I Singh, H Chen, C Zhang, W Ye, BW Hayes, J Liu, ...
Nature 600 (7887), 170-175, 2021
Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity
AL Kaplan, DN Confair, K Kim, X Barros-Álvarez, RM Rodriguiz, Y Yang, ...
Nature 610 (7932), 582-591, 2022
Chemoenzymatic Total Synthesis and Structural Diversification of Tylactone-Based Macrolide Antibiotics through Late-Stage Polyketide Assembly, Tailoring, and C H Functionalization
AN Lowell, MD DeMars, ST Slocum, F Yu, K Anand, JA Chemler, ...
Journal of the American Chemical Society 139 (23), 7913-7920, 2017
The activities of drug inactive ingredients on biological targets
J Pottel, D Armstrong, L Zou, A Fekete, XP Huang, H Torosyan, ...
Science 369 (6502), 403-413, 2020
Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site
R Uprety, T Che, SA Zaidi, SG Grinnell, BR Varga, A Faouzi, ST Slocum, ...
Elife 10, e56519, 2021
Structure-based design of bitopic ligands for the µ-opioid receptor
A Faouzi, H Wang, SA Zaidi, JF DiBerto, T Che, Q Qu, MJ Robertson, ...
Nature 613 (7945), 767-774, 2023
Molecular insights into psychedelic drug action
ST Slocum, JF DiBerto, BL Roth
Journal of Neurochemistry 162 (1), 24-38, 2022
Oxidative metabolism as a modulator of kratom’s biological actions
S Chakraborty, R Uprety, ST Slocum, T Irie, V Le Rouzic, X Li, LL Wilson, ...
Journal of Medicinal Chemistry 64 (22), 16553-16572, 2021
Design, synthesis, and characterization of ogerin-based positive allosteric modulators for G protein-coupled receptor 68 (GPR68)
X Yu, XP Huang, TP Kenakin, ST Slocum, X Chen, ML Martini, J Liu, J Jin
Journal of medicinal chemistry 62 (16), 7557-7574, 2019
Structure-Based Design of a Chemical Probe Set for the 5-HT5A Serotonin Receptor
A Levit Kaplan, RT Strachan, JM Braz, V Craik, S Slocum, T Mangano, ...
Journal of medicinal chemistry 65 (5), 4201-4217, 2022
5-HT2A SNPs Alter the Pharmacological Signaling of Potentially Therapeutic Psychedelics
GP Schmitz, MK Jain, ST Slocum, BL Roth
ACS Chemical Neuroscience 13 (16), 2386-2398, 2022
Neurotensin receptor allosterism revealed in complex with a biased allosteric modulator
BE Krumm, JF DiBerto, RHJ Olsen, HJ Kang, ST Slocum, S Zhang, ...
Biochemistry 62 (7), 1233-1248, 2023
Chemoenzymatic dissection of polyketide β-branching in the bryostatin pathway
ST Slocum, AN Lowell, A Tripathi, VV Shende, JL Smith, DH Sherman
Methods in enzymology 604, 207-236, 2018
Synthesis and Pharmacological Evaluation of Fluorinated Quinoxaline‐Based κ‐Opioid Receptor (KOR) Agonists Designed for PET Studies
G Tangherlini, F Börgel, D Schepmann, S Slocum, T Che, S Wagner, ...
ChemMedChem 15 (19), 1834-1853, 2020
The system can't perform the operation now. Try again later.
Articles 1–20