| Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo FJ Najm, M Madhavan, A Zaremba, E Shick, RT Karl, DC Factor, TE Miller, ... Nature 522 (7555), 216-220, 2015 | 408 | 2015 |
| Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells FJ Najm, AM Lager, A Zaremba, K Wyatt, AV Caprariello, DC Factor, ... Nature biotechnology 31 (5), 426-433, 2013 | 314 | 2013 |
| Induction of myelinating oligodendrocytes in human cortical spheroids M Madhavan, ZS Nevin, HE Shick, E Garrison, C Clarkson-Paredes, ... Nature methods 15 (9), 700-706, 2018 | 260 | 2018 |
| Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling SC Mack, KW Pajtler, L Chavez, K Okonechnikov, KC Bertrand, X Wang, ... Nature 553 (7686), 101-105, 2018 | 194 | 2018 |
| Transcription elongation factors represent in vivo cancer dependencies in glioblastoma TE Miller, BB Liau, LC Wallace, AR Morton, Q Xie, D Dixit, DC Factor, ... Nature 547 (7663), 355-359, 2017 | 191 | 2017 |
| Accumulation of 8, 9-unsaturated sterols drives oligodendrocyte formation and remyelination Z Hubler, D Allimuthu, I Bederman, MS Elitt, M Madhavan, KC Allan, ... Nature 560 (7718), 372-376, 2018 | 184 | 2018 |
| Epigenomic comparison reveals activation of “seed” enhancers during transition from naive to primed pluripotency DC Factor, O Corradin, GE Zentner, A Saiakhova, L Song, JG Chenoweth, ... Cell stem cell 14 (6), 854-863, 2014 | 164 | 2014 |
| The epigenetic regulator UHRF1 promotes ubiquitination-mediated degradation of the tumor-suppressor protein promyelocytic leukemia protein D Guan, D Factor, Y Liu, Z Wang, HY Kao Oncogene 32 (33), 3819-3828, 2013 | 78 | 2013 |
| Modeling the mutational and phenotypic landscapes of Pelizaeus-Merzbacher disease with human iPSC-derived oligodendrocytes ZS Nevin, DC Factor, RT Karl, P Douvaras, J Laukka, MS Windrem, ... The American Journal of Human Genetics 100 (4), 617-634, 2017 | 64 | 2017 |
| RBPJ maintains brain tumor–initiating cells through CDK9-mediated transcriptional elongation Q Xie, Q Wu, L Kim, TE Miller, BB Liau, SC Mack, K Yang, DC Factor, ... The Journal of clinical investigation 126 (7), 2757-2772, 2016 | 54 | 2016 |
| Cell type-specific intralocus interactions reveal oligodendrocyte mechanisms in MS DC Factor, AM Barbeau, KC Allan, LR Hu, M Madhavan, AT Hoang, ... Cell 181 (2), 382-395. e21, 2020 | 38 | 2020 |
| Chemical screening identifies enhancers of mutant oligodendrocyte survival and unmasks a distinct pathological phase in Pelizaeus-Merzbacher disease MS Elitt, HE Shick, M Madhavan, KC Allan, BLL Clayton, C Weng, ... Stem Cell Reports 11 (3), 711-726, 2018 | 33 | 2018 |
| NG2 expression in NG2 glia is regulated by binding of SoxE and bHLH transcription factors to a Cspg4 intronic enhancer H Gotoh, WM Wood, KD Patel, DC Factor, LL Boshans, T Nomura, ... Glia 66 (12), 2684-2699, 2018 | 29 | 2018 |
| The chromatin environment around interneuron genes in oligodendrocyte precursor cells and their potential for interneuron reprograming LL Boshans, DC Factor, V Singh, J Liu, C Zhao, I Mandoiu, QR Lu, ... Frontiers in Neuroscience 13, 829, 2019 | 15 | 2019 |
| Generation and characterization of epiblast stem cells from blastocyst-stage mouse embryos DC Factor, FJ Najm, PJ Tesar Epiblast Stem Cells: Methods and Protocols, 1-13, 2013 | 9 | 2013 |
| Cellular Maturation of Oligodendrocytes is Governed by Transient Gene Melting KC Allan, TE Miller, AR Morton, MA Scavuzzo, MS Elitt, BLL Clayton, ... bioRxiv, 2022.11. 17.516981, 2022 | 1 | 2022 |
| Understanding Epigenetic Controllers of Stem Cell Fate and Function DC Factor Case Western Reserve University, 2018 | 1 | 2018 |
| Chromatin regulation by long non-coding RNAs DC Factor, PJ Tesar, AM Khalil Molecular Biology of Long Non-coding RNAs, 1-13, 2013 | 1 | 2013 |
| Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte Formation R Dorel, D Sun, N Carruthers, GM Castanedo, PMU Ung, DC Factor, T Li, ... Journal of Medicinal Chemistry, 2024 | | 2024 |
| Cell Type Specificity of Intralocus Interactions Reveals Oligodendrocyte Intrinsic Mechanisms For Multiple Sclerosis DC Factor, AM Barbeau, M Madhavan, S Nisraiyya, PA Hall, FJ Najm, ... | | 2019 |
Peter ScacheriProfessor, Case Western Reserve UniversityVerified email at case.edu
