| Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord KA Kigerl, JC Gensel, DP Ankeny, JK Alexander, DJ Donnelly, ... Journal of Neuroscience 29 (43), 13435-13444, 2009 | 2428 | 2009 |
| Pattern recognition receptors and central nervous system repair KA Kigerl, JP de Rivero Vaccari, WD Dietrich, PG Popovich, RW Keane Experimental Neurology 258, 5-16, 2014 | 482 | 2014 |
| Rats and mice exhibit distinct inflammatory reactions after spinal cord injury JM Sroga, T Jones, KA Kigerl, VM McGaughy, PG Popovich Journal of Comparative Neurology 462 (2), 223-240, 2003 | 449 | 2003 |
| Toll‐like receptor (TLR)‐2 and TLR‐4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury KA Kigerl, W Lai, S Rivest, RP Hart, AR Satoskar, PG Popovich Journal of neurochemistry 102 (1), 37-50, 2007 | 343 | 2007 |
| Comparative analysis of lesion development and intraspinal inflammation in four strains of mice following spinal contusion injury KA Kigerl, VM McGAUGHY, PG Popovich Journal of Comparative Neurology 494 (4), 578-594, 2006 | 321 | 2006 |
| Gut dysbiosis impairs recovery after spinal cord injury KA Kigerl, JCE Hall, L Wang, X Mo, Z Yu, PG Popovich Journal of Experimental Medicine 213 (12), 2603-2620, 2016 | 299 | 2016 |
| Deficient CX3CR1 signaling promotes recovery after mouse spinal cord injury by limiting the recruitment and activation of Ly6Clo/iNOS+ macrophages DJ Donnelly, EE Longbrake, TM Shawler, KA Kigerl, W Lai, CA Tovar, ... Journal of Neuroscience 31 (27), 9910-9922, 2011 | 235 | 2011 |
| Stress exacerbates neuropathic pain via glucocorticoid and NMDA receptor activation JK Alexander, AC DeVries, KA Kigerl, JM Dahlman, PG Popovich Brain, behavior, and immunity 23 (6), 851-860, 2009 | 175 | 2009 |
| Gut microbiota are disease-modifying factors after traumatic spinal cord injury KA Kigerl, K Mostacada, PG Popovich Neurotherapeutics 15, 60-67, 2018 | 114 | 2018 |
| Fecal transplant prevents gut dysbiosis and anxiety-like behaviour after spinal cord injury in rats EKA Schmidt, A Torres-Espin, PJF Raposo, KL Madsen, KA Kigerl, ... PloS one 15 (1), e0226128, 2020 | 106 | 2020 |
| Microglia coordinate cellular interactions during spinal cord repair in mice FH Brennan, Y Li, C Wang, A Ma, Q Guo, Y Li, N Pukos, WA Campbell, ... Nature Communications 13 (1), 1-20, 2022 | 90 | 2022 |
| Progranulin expression is upregulated after spinal contusion in mice SB Naphade, KA Kigerl, LB Jakeman, SK Kostyk, PG Popovich, J Kuret Acta neuropathologica 119, 123-133, 2010 | 79 | 2010 |
| System x c− regulates microglia and macrophage glutamate excitotoxicity in vivo KA Kigerl, DP Ankeny, SK Garg, P Wei, Z Guan, W Lai, DM McTigue, ... Experimental neurology 233 (1), 333-341, 2012 | 74 | 2012 |
| Macrophage migration inhibitory factor (MIF) is essential for inflammatory and neuropathic pain and enhances pain in response to stress JK Alexander, GM Cox, JB Tian, AM Zha, P Wei, KA Kigerl, MK Reddy, ... Experimental neurology 236 (2), 351-362, 2012 | 71 | 2012 |
| High mobility group box-1 (HMGB1) is increased in injured mouse spinal cord and can elicit neurotoxic inflammation KA Kigerl, W Lai, LM Wallace, H Yang, PG Popovich Brain, behavior, and immunity 72, 22-33, 2018 | 65 | 2018 |
| Achieving CNS axon regeneration by manipulating convergent neuro-immune signaling JC Gensel, KA Kigerl, SS Mandrekar-Colucci, AD Gaudet, PG Popovich Cell and tissue research 349, 201-213, 2012 | 63 | 2012 |
| TLR4 deficiency impairs oligodendrocyte formation in the injured spinal cord JS Church, KA Kigerl, JK Lerch, PG Popovich, DM McTigue Journal of Neuroscience 36 (23), 6352-6364, 2016 | 59 | 2016 |
| p53 Regulates the neuronal intrinsic and extrinsic responses affecting the recovery of motor function following spinal cord injury EM Floriddia, KI Rathore, A Tedeschi, G Quadrato, A Wuttke, ... Journal of Neuroscience 32 (40), 13956-13970, 2012 | 59 | 2012 |
| Toll-like receptors in spinal cord injury KA Kigerl, PG Popovich Toll-like Receptors: Roles in Infection and Neuropathology, 121-136, 2009 | 57 | 2009 |
| The spinal cord-gut-immune axis as a master regulator of health and neurological function after spinal cord injury KA Kigerl, K Zane, K Adams, MB Sullivan, PG Popovich Experimental neurology 323, 113085, 2020 | 56 | 2020 |
