SUMO-mediated regulation of NLRP3 modulates inflammasome activity R Barry, SW John, G Liccardi, T Tenev, I Jaco, CH Chen, J Choi, ... Nature communications 9 (1), 3001, 2018 | 171 | 2018 |
Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling P Kasperkiewicz, M Poreba, SJ Snipas, H Parker, CC Winterbourn, ... Proceedings of the National Academy of Sciences 111 (7), 2518-2523, 2014 | 164 | 2014 |
Mechanism and specificity of the human paracaspase MALT1 J Hachmann, SJ Snipas, BJ van Raam, EM Cancino, EJ Houlihan, ... Biochemical Journal 443 (1), 287-295, 2012 | 105 | 2012 |
Toolbox of fluorescent probes for parallel imaging reveals uneven location of serine proteases in neutrophils P Kasperkiewicz, Y Altman, M D’Angelo, GS Salvesen, M Drag Journal of the American Chemical Society 139 (29), 10115-10125, 2017 | 92 | 2017 |
Small molecule active site directed tools for studying human caspases M Poreba, A Szalek, P Kasperkiewicz, W Rut, GS Salvesen, M Drag Chemical reviews 115 (22), 12546-12629, 2015 | 85 | 2015 |
Unnatural amino acids increase sensitivity and provide for the design of highly selective caspase substrates M Poreba, P Kasperkiewicz, SJ Snipas, D Fasci, GS Salvesen, M Drag Cell Death & Differentiation 21 (9), 1482-1492, 2014 | 83 | 2014 |
Selective imaging of cathepsin L in breast cancer by fluorescent activity-based probes M Poreba, W Rut, M Vizovisek, K Groborz, P Kasperkiewicz, D Finlay, ... Chemical Science 9 (8), 2113-2129, 2018 | 70 | 2018 |
Highly sensitive and adaptable fluorescence-quenched pair discloses the substrate specificity profiles in diverse protease families M Poreba, A Szalek, W Rut, P Kasperkiewicz, I Rutkowska-Wlodarczyk, ... Scientific reports 7 (1), 1-13, 2017 | 67 | 2017 |
SARS hCoV papain-like protease is a unique Lys48 linkage-specific di-distributive deubiquitinating enzyme M Békés, W Rut, P Kasperkiewicz, MPC Mulder, H Ovaa, M Drag, ... Biochemical Journal 468 (2), 215-226, 2015 | 66 | 2015 |
Counter selection substrate library strategy for developing specific protease substrates and probes M Poreba, R Solberg, W Rut, NN Lunde, P Kasperkiewicz, SJ Snipas, ... Cell chemical biology 23 (8), 1023-1035, 2016 | 60 | 2016 |
Extended substrate specificity and first potent irreversible inhibitor/activity-based probe design for Zika virus NS2B-NS3 protease W Rut, L Zhang, P Kasperkiewicz, M Poreba, R Hilgenfeld, M Drąg Antiviral research 139, 88-94, 2017 | 59 | 2017 |
Design of a selective substrate and activity based probe for human neutrophil serine protease 4 P Kasperkiewicz, M Poreba, SJ Snipas, SJ Lin, D Kirchhofer, ... PLoS One 10 (7), e0132818, 2015 | 58 | 2015 |
Emerging challenges in the design of selective substrates, inhibitors and activity‐based probes for indistinguishable proteases P Kasperkiewicz, M Poreba, K Groborz, M Drag The FEBS journal 284 (10), 1518-1539, 2017 | 53 | 2017 |
Design of Selective Substrates and Activity-Based Probes for Hydrolase Important for Pathogenesis 1 (HIP1) from Mycobacterium tuberculosis CS Lentz, AA Ordonez, P Kasperkiewicz, F La Greca, AJ O’Donoghue, ... ACS infectious diseases 2 (11), 807-815, 2016 | 48 | 2016 |
Positional scanning substrate combinatorial library (PS-SCL) approach to define caspase substrate specificity M Poręba, A Szalek, P Kasperkiewicz, M Drąg Caspases, Paracaspases, and Metacaspases: Methods and Protocols, 41-59, 2014 | 35 | 2014 |
The elastase-PK101 structure: mechanism of an ultrasensitive activity-based probe revealed BC Lechtenberg, P Kasperkiewicz, H Robinson, M Drag, SJ Riedl ACS Chemical Biology 10 (4), 945-951, 2015 | 30 | 2015 |
Effects of curcumin based PDT on the viability and the organization of actin in melanotic (A375) and amelanotic melanoma (C32)–in vitro studies W Szlasa, S Supplitt, M Drąg-Zalesińska, D Przystupski, K Kotowski, ... Biomedicine & Pharmacotherapy 132, 110883, 2020 | 29 | 2020 |
Noninvasive optical detection of granzyme B from natural killer cells with enzyme-activated fluorogenic probes T Janiszewski, S Kołt, D Kaiserman, SJ Snipas, S Li, J Kulbacka, J Saczko, ... Journal of Biological Chemistry 295 (28), 9567-9582, 2020 | 28 | 2020 |
Selective substrates and activity-based probes for imaging of the human constitutive 20S proteasome in cells and blood samples W Rut, M Poreba, P Kasperkiewicz, SJ Snipas, M Drag Journal of Medicinal Chemistry 61 (12), 5222-5234, 2018 | 28 | 2018 |
Substrate specificity and possible heterologous targets of phytaspase, a plant cell death protease RA Galiullina, P Kasperkiewicz, NV Chichkova, A Szalek, ... Journal of Biological Chemistry 290 (41), 24806-24815, 2015 | 28 | 2015 |