Antimutagenic compounds and their possible mechanisms of action K Słoczyńska, B Powroźnik, E Pękala, AM Waszkielewicz Journal of applied genetics 55, 273-285, 2014 | 208 | 2014 |
Fibroblast-to-myofibroblast transition in bronchial asthma M Michalik, K Wójcik-Pszczoła, M Paw, D Wnuk, P Koczurkiewicz, ... Cellular and Molecular Life Sciences 75, 3943-3961, 2018 | 149 | 2018 |
Cinnamic acid derivatives in cosmetics: current use and future prospects A Gunia‐Krzyżak, K Słoczyńska, J Popiół, P Koczurkiewicz, H Marona, ... International Journal of Cosmetic Science 40 (4), 356-366, 2018 | 133 | 2018 |
Piperlongumine (piplartine) as a lead compound for anticancer agents–Synthesis and properties of analogues: A mini-review K Piska, A Gunia-Krzyżak, P Koczurkiewicz, K Wójcik-Pszczoła, E Pękala European journal of medicinal chemistry 156, 13-20, 2018 | 114 | 2018 |
RNAi in clinical studies P Kubowicz, D Zelaszczyk, E Pekala Current medicinal chemistry 20 (14), 1801-1816, 2013 | 82 | 2013 |
Metabolic stability and its role in the discovery of new chemical entities K Słoczyńska, A Gunia-Krzyżak, P Koczurkiewicz, K Wójcik-Pszczoła, ... Acta Pharmaceutica 69 (3), 345-361, 2019 | 70 | 2019 |
Metabolic carbonyl reduction of anthracyclines—role in cardiotoxicity and cancer resistance. Reducing enzymes as putative targets for novel cardioprotective and … K Piska, P Koczurkiewicz, A Bucki, K Wójcik-Pszczoła, M Kołaczkowski, ... Investigational new drugs 35, 375-385, 2017 | 64 | 2017 |
Anticonvulsant activity of some xanthone derivatives H Marona, E Pękala, L Antkiewicz-Michaluk, M Walczak, E Szneler Bioorganic & medicinal chemistry 16 (15), 7234-7244, 2008 | 51 | 2008 |
Imidazo-thiazine,-diazinone and-diazepinone derivatives. Synthesis, structure and benzodiazepine receptor binding K Kieć-Kononowicz, J Karolak-Wojciechowska, CE Müller, B Schumacher, ... European journal of medicinal chemistry 36 (5), 407-419, 2001 | 46 | 2001 |
Autophagy modulating agents as chemosensitizers for cisplatin therapy in cancer BM Gąsiorkiewicz, P Koczurkiewicz-Adamczyk, K Piska, E Pękala Investigational new drugs 39 (2), 538-563, 2021 | 42 | 2021 |
Novel non-sulfonamide 5-HT6 receptor partial inverse agonist in a group of imidazo [4, 5-b] pyridines with cognition enhancing properties D Vanda, M Soural, V Canale, S Chaumont-Dubel, G Satała, T Kos, ... European Journal of Medicinal Chemistry 144, 716-729, 2018 | 42 | 2018 |
Synthesis, structure and antiarrhythmic properties evaluation of new basic derivatives of 5, 5-diphenylhydantoin K Kieć-Kononowicz, K Stadnicka, A Mitka, E Pękala, B Filipek, J Sapa, ... European journal of medicinal chemistry 38 (6), 555-566, 2003 | 40 | 2003 |
New developments in A1 and A2 adenosine receptor antagonists K Kieć-Kononowicz, A Drabczyńska, E Pękala, B Michalak, CE Müller, ... Pure and Applied Chemistry 73 (9), 1411-1420, 2001 | 39 | 2001 |
Design, synthesis and biological activity of new amides derived from 3-methyl-3-phenyl-2, 5-dioxo-pyrrolidin-1-yl-acetic acid J Obniska, A Rapacz, S Rybka, B Powroźnik, E Pękala, B Filipek, ... European Journal of Medicinal Chemistry 102, 14-25, 2015 | 38 | 2015 |
Synthesis and biological activity of tricyclic aryloimidazo-, pyrimido-, and diazepinopurinediones A Drabczyńska, CE Müller, SK Lacher, B Schumacher, ... Bioorganic & medicinal chemistry 14 (21), 7258-7281, 2006 | 37 | 2006 |
Design, synthesis, and biological evaluation of fluorinated imidazo [1, 2-a] pyridine derivatives with potential antipsychotic activity M Marcinkowska, M Kołaczkowski, K Kamiński, A Bucki, M Pawłowski, ... European Journal of Medicinal Chemistry 124, 456-467, 2016 | 35 | 2016 |
A novel, pan-PDE inhibitor exerts anti-fibrotic effects in human lung fibroblasts via inhibition of TGF-β signaling and activation of cAMP/PKA signaling K Wójcik-Pszczoła, G Chłoń-Rzepa, A Jankowska, M Ślusarczyk, ... International journal of molecular sciences 21 (11), 4008, 2020 | 34 | 2020 |
Synergistic anticancer activity of doxorubicin and piperlongumine on DU-145 prostate cancer cells–the involvement of carbonyl reductase 1 inhibition K Piska, P Koczurkiewicz, D Wnuk, E Karnas, A Bucki, K Wójcik-Pszczoła, ... Chemico-Biological Interactions 300, 40-48, 2019 | 34 | 2019 |
Search for new tools to combat Gram-negative resistant bacteria among amine derivatives of 5-arylidenehydantoin J Handzlik, E Szymańska, S Alibert, J Chevalier, E Otrębska, E Pękala, ... Bioorganic & medicinal chemistry 21 (1), 135-145, 2013 | 34 | 2013 |
Synthesis and biological properties of new N-Mannich bases derived from 3-methyl-3-phenyl-and 3, 3-dimethyl-succinimides. Part V K Kamiński, J Obniska, I Chlebek, P Liana, E Pękala European Journal of Medicinal Chemistry 66, 12-21, 2013 | 33 | 2013 |