A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs E Girardi, A César-Razquin, S Lindinger, K Papakostas, J Konecka, ... Nature chemical biology 16 (4), 469-478, 2020 | 119 | 2020 |
An overview of cell-based assay platforms for the solute carrier family of transporters V Dvorak, T Wiedmer, A Ingles-Prieto, P Altermatt, H Batoulis, F Bärenz, ... Frontiers in pharmacology 12, 722889, 2021 | 51 | 2021 |
Structural and molecular aspects of betaine-GABA transporter 1 (BGT1) and its relation to brain function S Kickinger, E Hellsberg, B Frølund, A Schousboe, GF Ecker, ... Neuropharmacology 161, 107644, 2019 | 31 | 2019 |
Structure–activity relationship, pharmacological characterization, and molecular modeling of noncompetitive inhibitors of the betaine/γ-aminobutyric acid transporter 1 (BGT1) L Jørgensen, A Al-Khawaja, S Kickinger, SB Vogensen, ... Journal of Medicinal Chemistry 60 (21), 8834-8846, 2017 | 21 | 2017 |
Development of non-GAT1-selective inhibitors: challenges and achievements M Damgaard, AS Haugaard, S Kickinger, A Al-Khawaja, MEK Lie, ... Glial Amino Acid Transporters, 315-332, 2017 | 15 | 2017 |
Pharmacological characterization of a betaine/GABA transporter 1 (BGT1) inhibitor displaying an unusual biphasic inhibition profile and anti-seizure effects MEK Lie, S Kickinger, J Skovgaard-Petersen, GF Ecker, RP Clausen, ... Neurochemical Research 45 (7), 1551-1565, 2020 | 10 | 2020 |
Molecular determinants and pharmacological analysis for a class of competitive non-transported bicyclic inhibitors of the betaine/GABA transporter BGT1 S Kickinger, MEK Lie, A Suemasa, A Al-Khawaja, K Fujiwara, ... Frontiers in Chemistry 9, 736457, 2021 | 6 | 2021 |
Exploring the molecular determinants for subtype-selectivity of 2-amino-1, 4, 5, 6-tetrahydropyrimidine-5-carboxylic acid analogs as betaine/GABA transporter 1 (BGT1) substrate … S Kickinger, A Al-Khawaja, AS Haugaard, MEK Lie, F Bavo, R Löffler, ... Scientific Reports 10 (1), 12992, 2020 | 6 | 2020 |
Rational Search for Betaine/GABA Transporter 1 Inhibitors─In Vitro Evaluation of Selected Hit Compound K Łątka, S Kickinger, Z Rzepka, P Zaręba, G Latacz, A Siwek, M Wolak, ... ACS Chemical Neuroscience, 2024 | 1 | 2024 |
Synthesis, pharmacological activity and molecular modeling studies of a series of 2-amino-1, 4, 5, 6-tetrahydropyrimidine-5-carboxylic acid analogues as betaine/GABA … S Kickinger, A Al-Khawaja, AS Haugaard, R Loeffler, M Damgaard, ... American Chemical Society. Abstracts of Papers (at the National Meeting) 256, 2018 | 1 | 2018 |
Proteochemometric modeling strengthens the role of Q299 for GABA transporter subtype selectivity S Kickinger, A Seiler, D Digles, GF Ecker bioRxiv, 2024.08. 13.607728, 2024 | | 2024 |
Correction: Structural and stereochemical determinants for hGAT3 inhibition: development of novel conformationally constrained and substituted analogs of (S)-isoserine F Bavo, S Kickinger, MEK Lie, C Avgerinos, Y Xu, KS Wilhelmsen, ... Medicinal Chemistry Research 32 (12), 2587-2587, 2023 | | 2023 |
Structural and stereochemical determinants for hGAT3 inhibition: development of novel conformationally constrained and substituted analogs of (S)-isoserine F Bavo, S Kickinger, MEK Lie, C Avgerinos, Y Xu, KS Wilhelmsen, ... Medicinal Chemistry Research 32 (11), 2299-2324, 2023 | | 2023 |
Functional modulation of a pH-sensitive ion channel by a transporter family MH Poulsen, F Xue, SR Maurya, S Kickinger, S Usher, P Wellendorph, ... Biophysical Journal 122 (3), 249a, 2023 | | 2023 |
An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of Transporters. Front. Pharmacol. 12: 722889. doi: 10.3389/fphar. 2021.722889 V Dvorak, T Wiedmer, A Ingles-Prieto, P Altermatt, H Batoulis, F Bärenz, ... Frontiers in Pharmacology| www. frontiersin. org 12, 2021 | | 2021 |
Proteochemometric modeling of GABA transporters G Ecker, S Kickinger, A Seiler American Chemical Society SciMeetings 1 (1), 2020 | | 2020 |
Unraveling the Molecular Determinants for GABA Transporter Subtype Selectivity S Kickinger, A Al-Khawaja, AS Haugaard, MEK Lie, F Bavo, R Löffler, ... Biophysical Journal 118 (3), 130a, 2020 | | 2020 |
Linked Open Data: Ligand-Transporter Interaction Profiling and Beyond S Kickinger, E Hellsberg, S Jain, GF Ecker Multi-Target Drug Design Using Chem-Bioinformatic Approaches, 405-417, 2019 | | 2019 |