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Stefanie Kickinger
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A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs
E Girardi, A César-Razquin, S Lindinger, K Papakostas, J Konecka, ...
Nature chemical biology 16 (4), 469-478, 2020
1192020
An overview of cell-based assay platforms for the solute carrier family of transporters
V Dvorak, T Wiedmer, A Ingles-Prieto, P Altermatt, H Batoulis, F Bärenz, ...
Frontiers in pharmacology 12, 722889, 2021
512021
Structural and molecular aspects of betaine-GABA transporter 1 (BGT1) and its relation to brain function
S Kickinger, E Hellsberg, B Frølund, A Schousboe, GF Ecker, ...
Neuropharmacology 161, 107644, 2019
312019
Structure–activity relationship, pharmacological characterization, and molecular modeling of noncompetitive inhibitors of the betaine/γ-aminobutyric acid transporter 1 (BGT1)
L Jørgensen, A Al-Khawaja, S Kickinger, SB Vogensen, ...
Journal of Medicinal Chemistry 60 (21), 8834-8846, 2017
212017
Development of non-GAT1-selective inhibitors: challenges and achievements
M Damgaard, AS Haugaard, S Kickinger, A Al-Khawaja, MEK Lie, ...
Glial Amino Acid Transporters, 315-332, 2017
152017
Pharmacological characterization of a betaine/GABA transporter 1 (BGT1) inhibitor displaying an unusual biphasic inhibition profile and anti-seizure effects
MEK Lie, S Kickinger, J Skovgaard-Petersen, GF Ecker, RP Clausen, ...
Neurochemical Research 45 (7), 1551-1565, 2020
102020
Molecular determinants and pharmacological analysis for a class of competitive non-transported bicyclic inhibitors of the betaine/GABA transporter BGT1
S Kickinger, MEK Lie, A Suemasa, A Al-Khawaja, K Fujiwara, ...
Frontiers in Chemistry 9, 736457, 2021
62021
Exploring the molecular determinants for subtype-selectivity of 2-amino-1, 4, 5, 6-tetrahydropyrimidine-5-carboxylic acid analogs as betaine/GABA transporter 1 (BGT1) substrate …
S Kickinger, A Al-Khawaja, AS Haugaard, MEK Lie, F Bavo, R Löffler, ...
Scientific Reports 10 (1), 12992, 2020
62020
Rational Search for Betaine/GABA Transporter 1 Inhibitors─In Vitro Evaluation of Selected Hit Compound
K Łątka, S Kickinger, Z Rzepka, P Zaręba, G Latacz, A Siwek, M Wolak, ...
ACS Chemical Neuroscience, 2024
12024
Synthesis, pharmacological activity and molecular modeling studies of a series of 2-amino-1, 4, 5, 6-tetrahydropyrimidine-5-carboxylic acid analogues as betaine/GABA …
S Kickinger, A Al-Khawaja, AS Haugaard, R Loeffler, M Damgaard, ...
American Chemical Society. Abstracts of Papers (at the National Meeting) 256, 2018
12018
Proteochemometric modeling strengthens the role of Q299 for GABA transporter subtype selectivity
S Kickinger, A Seiler, D Digles, GF Ecker
bioRxiv, 2024.08. 13.607728, 2024
2024
Correction: Structural and stereochemical determinants for hGAT3 inhibition: development of novel conformationally constrained and substituted analogs of (S)-isoserine
F Bavo, S Kickinger, MEK Lie, C Avgerinos, Y Xu, KS Wilhelmsen, ...
Medicinal Chemistry Research 32 (12), 2587-2587, 2023
2023
Structural and stereochemical determinants for hGAT3 inhibition: development of novel conformationally constrained and substituted analogs of (S)-isoserine
F Bavo, S Kickinger, MEK Lie, C Avgerinos, Y Xu, KS Wilhelmsen, ...
Medicinal Chemistry Research 32 (11), 2299-2324, 2023
2023
Functional modulation of a pH-sensitive ion channel by a transporter family
MH Poulsen, F Xue, SR Maurya, S Kickinger, S Usher, P Wellendorph, ...
Biophysical Journal 122 (3), 249a, 2023
2023
An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of Transporters. Front. Pharmacol. 12: 722889. doi: 10.3389/fphar. 2021.722889
V Dvorak, T Wiedmer, A Ingles-Prieto, P Altermatt, H Batoulis, F Bärenz, ...
Frontiers in Pharmacology| www. frontiersin. org 12, 2021
2021
Proteochemometric modeling of GABA transporters
G Ecker, S Kickinger, A Seiler
American Chemical Society SciMeetings 1 (1), 2020
2020
Unraveling the Molecular Determinants for GABA Transporter Subtype Selectivity
S Kickinger, A Al-Khawaja, AS Haugaard, MEK Lie, F Bavo, R Löffler, ...
Biophysical Journal 118 (3), 130a, 2020
2020
Linked Open Data: Ligand-Transporter Interaction Profiling and Beyond
S Kickinger, E Hellsberg, S Jain, GF Ecker
Multi-Target Drug Design Using Chem-Bioinformatic Approaches, 405-417, 2019
2019
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