Aldehyde sources, metabolism, molecular toxicity mechanisms, and possible effects on human health PJ O'Brien, AG Siraki, N Shangari Critical reviews in toxicology 35 (7), 609-662, 2005 | 786 | 2005 |
Dietary flavonoid iron complexes as cytoprotective superoxide radical scavengers MY Moridani, J Pourahmad, H Bui, A Siraki, PJ O’Brien Free Radical Biology and Medicine 34 (2), 243-253, 2003 | 340 | 2003 |
Molecular cytotoxic mechanisms of anticancer hydroxychalcones O Sabzevari, G Galati, MY Moridani, A Siraki, PJ O’Brien Chemico-biological interactions 148 (1-2), 57-67, 2004 | 170 | 2004 |
A conceptual framework for predicting the toxicity of reactive chemicals: modeling soft electrophilicity TW Schultz, RE Carlson, MTD Cronin, JLM Hermens, R Johnson, ... SAR and QSAR in Environmental Research 17 (4), 413-428, 2006 | 156 | 2006 |
Endogenous and endobiotic induced reactive oxygen species formation by isolated hepatocytes AG Siraki, J Pourahmad, TS Chan, S Khan, PJ O’Brien Free Radical Biology and Medicine 32 (1), 2-10, 2002 | 149 | 2002 |
Quantitative structure toxicity relationships for phenols in isolated rat hepatocytes MY Moridani, A Siraki, PJ O'Brien Chemico-biological interactions 145 (2), 213-223, 2003 | 120 | 2003 |
Comprehensive in vitro characterization of PD-L1 small molecule inhibitors A Ganesan, M Ahmed, I Okoye, E Arutyunova, D Babu, WL Turnbull, ... Scientific reports 9 (1), 12392, 2019 | 114 | 2019 |
Application of Quantitative Structure-Toxicity Relationships for the Comparison of the Cytotoxicity of 14 p-Benzoquinone Congeners in Primary Cultured Rat … AG Siraki, TS Chan, PJ O'brien Toxicological Sciences 81 (1), 148-159, 2004 | 94 | 2004 |
Quantitative structure toxicity relationships for catechols in isolated rat hepatocytes MY Moridani, A Siraki, T Chevaldina, H Scobie, PJ O’Brien Chemico-biological interactions 147 (3), 297-307, 2004 | 75 | 2004 |
Differential eNOS-signalling by platelet subpopulations regulates adhesion and aggregation A Radziwon-Balicka, G Lesyk, V Back, T Fong, EL Loredo-Calderon, ... Cardiovascular research 113 (14), 1719-1731, 2017 | 70 | 2017 |
Immunolocalization of hypochlorite-induced, catalase-bound free radical formation in mouse hepatocytes MG Bonini, AG Siraki, BS Atanassov, RP Mason Free Radical Biology and Medicine 42 (4), 530-540, 2007 | 65 | 2007 |
N-OXIDATION OF AROMATIC AMINES BY INTRACELLULAR OXIDASES AG Siraki, TS Chan, G Galati, S Teng, PJ O'Brien Drug metabolism reviews 34 (3), 549-564, 2002 | 64 | 2002 |
Prooxidant activity of free radicals derived from phenol-containing neurotransmitters AG Siraki, PJ O'Brien Toxicology 177 (1), 81-90, 2002 | 63 | 2002 |
The many roles of myeloperoxidase: from inflammation and immunity to biomarkers, drug metabolism and drug discovery AG Siraki Redox biology 46, 102109, 2021 | 59 | 2021 |
Application of quantitative structure–toxicity relationships for acute NSAID cytotoxicity in rat hepatocytes AG Siraki, T Chevaldina, PJ O’Brien Chemico-biological interactions 151 (3), 177-191, 2005 | 54 | 2005 |
Modulating carbonyl cytotoxicity in intact rat hepatocytes by inhibiting carbonyl-metabolizing enzymes. I. Aliphatic alkenals H Niknahad, AG Siraki, A Shuhendler, S Khan, S Teng, G Galati, ... Chemico-biological interactions 143, 107-117, 2003 | 52 | 2003 |
Accelerated cytotoxicity mechanism screening using drug metabolising enzyme modulators PJ O'Brien, AG Siraki Current drug metabolism 6 (2), 101-109, 2005 | 50 | 2005 |
Current status and future prospects of toxicogenomics in drug discovery SR Khan, A Baghdasarian, RP Fahlman, K Michail, AG Siraki Drug discovery today 19 (5), 562-578, 2014 | 44 | 2014 |
Free radical production from the interaction of 2-chloroethyl vesicants (mustard gas) with pyridine nucleotide-driven flavoprotein electron transport systems AA Brimfield, AM Mancebo, RP Mason, JJ Jiang, AG Siraki, MJ Novak Toxicology and applied pharmacology 234 (1), 128-134, 2009 | 38 | 2009 |
Aminoglutethimide-induced protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis AG Siraki, MG Bonini, JJ Jiang, M Ehrenshaft, RP Mason Chemical research in toxicology 20 (7), 1038-1045, 2007 | 38 | 2007 |