Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity R Yan, MJ Bienkowski, ME Shuck, H Miao, MC Tory, AM Pauley, ... Nature 402 (6761), 533-537, 1999 | 2048 | 1999 |
The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog C Öberg, J Li, A Pauley, E Wolf, M Gurney, U Lendahl Journal of Biological Chemistry 276 (38), 35847-35853, 2001 | 530 | 2001 |
SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation G Wu, S Lyapina, I Das, J Li, M Gurney, A Pauley, I Chui, RJ Deshaies, ... Molecular and cellular biology, 2001 | 443 | 2001 |
Distinction of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition from cyclooxygenase-2 inhibition in cells using a novel, selective mPGES-1 inhibitor G Mbalaviele, AM Pauley, AF Shaffer, BS Zweifel, S Mathialagan, ... Biochemical pharmacology 79 (10), 1445-1454, 2010 | 89 | 2010 |
SEL‐10 interacts with presenilin 1, facilitates its ubiquitination, and alters A‐beta peptide production J Li, AM Pauley, RL Myers, R Shuang, JR Brashler, R Yan, AE Buhl, ... Journal of neurochemistry 82 (6), 1540-1548, 2002 | 89 | 2002 |
Direct interaction of soluble human recombinant tau protein with Aβ 1–42 results in tau aggregation and hyperphosphorylation by tau protein kinase II KB Rank, AM Pauley, K Bhattacharya, Z Wang, DB Evans, TJ Fleck, ... FEBS letters 514 (2-3), 263-268, 2002 | 81 | 2002 |
The Candida albicans myristoyl-CoA: protein N-myristoyltransferase gene. Isolation and expression in Saccharomyces cerevisiae and Escherichia coli. RC Wiegand, C Carr, JC Minnerly, AM Pauley, CP Carron, CA Langner, ... Journal of Biological Chemistry 267 (12), 8591-8598, 1992 | 78 | 1992 |
Positive and negative regulation of the γ-secretase activity by nicastrin in a murine model J Li, GJ Fici, CA Mao, RL Myers, R Shuang, GP Donoho, AM Pauley, ... Journal of Biological Chemistry 278 (35), 33445-33449, 2003 | 68 | 2003 |
Autoactivation of human ADAM8: a novel pre-processing step is required for catalytic activity T Hall, JW Leone, JF Wiese, DW Griggs, LE Pegg, AM Pauley, ... Bioscience reports 29 (4), 217-228, 2009 | 26 | 2009 |
Structure of human ADAM-8 catalytic domain complexed with batimastat T Hall, HS Shieh, JE Day, N Caspers, JE Chrencik, JM Williams, LE Pegg, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2012 | 16 | 2012 |
ADAM8 substrate specificity: influence of pH on pre-processing and proteoglycan degradation T Hall, LE Pegg, AM Pauley, HD Fischer, AG Tomasselli, MD Zack Archives of biochemistry and biophysics 491 (1-2), 106-111, 2009 | 13 | 2009 |
Changes in γ-secretase activity and specificity caused by the introduction of consensus aspartyl protease active motif in Presenilin 1 DB Carter, E Dunn, AM Pauley, DD McKinley, TJ Fleck, BR Ellerbrook, ... Molecular Neurodegeneration 3, 1-12, 2008 | 13 | 2008 |
Human sel-10 polypeptides and polynucleotides that encode them ME Gurney, AM Pauley, J Li US Patent 6,730,778, 2004 | 1 | 2004 |
Human sel-10 polypeptides and polynucleotides that encode them ME Gurney, AM Pauley, J Li US Patent 6,638,731, 2003 | 1 | 2003 |
Presenilin enhancers Pen-1 and Pen-2 and their roles in a-beta production JH Li, R Myers, RQ Shuang, D Carter, D McKinley, R Hiebsch, ... NEUROBIOLOGY OF AGING 23 (1), S206-S206, 2002 | 1 | 2002 |
Human sel-10 polypeptides and polynucleotides that encode them M Gurney, A Pauley, J Li US Patent App. 10/653,676, 2005 | | 2005 |
Human sel-10 polypeptides and polynucleotides that encode them M Gurney, A Pauley, J Li US Patent App. 10/653,496, 2004 | | 2004 |
Human sel-10 polypeptides and polynucleotides that encode them M Gurney, A Pauley, J Li US Patent App. 10/653,517, 2004 | | 2004 |
Human sel-10 polypeptides and polynucleotides that encode them M Gurney, A Pauley, J Li US Patent App. 10/653,497, 2004 | | 2004 |