Nucleocapsid and Spike Proteins of the Coronavirus SARS-CoV-2 Induce IL6 in Monocytes and Macrophages—Potential Implications for Cytokine Storm Syndrome I Karwaciak, A Sałkowska, K Karaś, J Dastych, M Ratajewski Vaccines 9 (1), 54, 2021 | 57 | 2021 |
Identification of novel molecular markers of human Th17 cells A Sałkowska, K Karaś, I Karwaciak, A Walczak-Drzewiecka, M Krawczyk, ... Cells 9 (7), 1611, 2020 | 35 | 2020 |
Targeting EGFR in melanoma–the sea of possibilities to overcome drug resistance J Pastwińska, K Karaś, I Karwaciak, M Ratajewski Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1877 (4), 188754, 2022 | 31 | 2022 |
SIRT2 contributes to the resistance of melanoma cells to the multikinase inhibitor dasatinib I Karwaciak, A Sałkowska, K Karaś, M Sobalska-Kwapis, ... Cancers 11 (5), 673, 2019 | 31 | 2019 |
Differentiation stage-specific effect of histone deacetylase inhibitors on the expression of RORγT in human lymphocytes A Sałkowska, K Karaś, A Walczak-Drzewiecka, J Dastych, M Ratajewski Journal of Leukocyte Biology 102 (6), 1487-1495, 2017 | 31 | 2017 |
Cardiac glycosides with target at direct and indirect interactions with nuclear receptors K Karaś, A Sałkowska, J Dastych, RA Bachorz, M Ratajewski Biomedicine & Pharmacotherapy 127, 110106, 2020 | 30 | 2020 |
The cardenolides strophanthidin, digoxigenin and dihydroouabain act as activators of the human RORγ/RORγT receptors K Karaś, A Sałkowska, A Walczak-Drzewiecka, K Ryba, J Dastych, ... Toxicology Letters 295, 314-324, 2018 | 28 | 2018 |
SARS-CoV-2 Proteins Induce IFNG in Th1 Lymphocytes Generated from CD4+ Cells from Healthy, Unexposed Polish Donors A Sałkowska, I Karwaciak, K Karaś, J Dastych, M Ratajewski Vaccines 8 (4), 673, 2020 | 21 | 2020 |
Digoxin, an overlooked agonist of RORγ/RORγT K Karaś, A Sałkowska, M Sobalska-Kwapis, A Walczak-Drzewiecka, ... Frontiers in Pharmacology 9, 1460, 2019 | 14 | 2019 |
Chlorpromazine, a clinically approved drug, inhibits SARS-CoV-2 nucleocapsid-mediated induction of IL-6 in human monocytes I Karwaciak, K Karaś, A Sałkowska, J Pastwińska, M Ratajewski Molecules 27 (12), 3651, 2022 | 11 | 2022 |
The dichotomous nature of AZ5104 (an EGFR inhibitor) towards RORγ and RORγT K Karaś, A Sałkowska, I Karwaciak, A Walczak-Drzewiecka, J Dastych, ... International Journal of Molecular Sciences 20 (22), 5780, 2019 | 11 | 2019 |
Nucleoside 5′-O-monophosphorothioates as modulators of the P2Y14 receptor and mast cell degranulation E Gendaszewska-Darmach, E Węgłowska, A Walczak-Drzewiecka, ... Oncotarget 7 (43), 69358, 2016 | 10 | 2016 |
Targeting SIRT2 sensitizes melanoma cells to cisplatin via an EGFR-dependent mechanism I Karwaciak, A Sałkowska, K Karaś, J Dastych, M Ratajewski International Journal of Molecular Sciences 22 (9), 5034, 2021 | 9 | 2021 |
Trichostatin A inhibits expression of the human SLC2A5 gene via SNAI1/SNAI2 transcription factors and sensitizes colon cancer cells to platinum compounds K Chałaśkiewicz, K Karaś, M Zakłos-Szyda, I Karwaciak, J Pastwińska, ... European Journal of Pharmacology 949, 175728, 2023 | 7 | 2023 |
Identification of corosolic and oleanolic acids as molecules antagonizing the human RORγT nuclear receptor using the calculated fingerprints of the molecular similarity J Pastwińska, K Karaś, A Sałkowska, I Karwaciak, K Chałaśkiewicz, ... International Journal of Molecular Sciences 23 (3), 1906, 2022 | 7 | 2022 |
Anti-hepatocellular carcinoma activity of the cyclin-dependent kinase inhibitor AT7519 K Karaś, I Karwaciak, K Chałaśkiewicz, A Sałkowska, J Pastwińska, ... Biomedicine & Pharmacotherapy 164, 115002, 2023 | 5 | 2023 |
Anticancer imidazoacridinone C-1311 is effective in androgen-dependent and androgen-independent prostate cancer cells M Niemira, B Borowa-Mazgaj, SB Bader, A Moszyńska, M Ratajewski, ... Biomedicines 8 (9), 292, 2020 | 5 | 2020 |
Functional Analysis of the rs774872314, rs116171003, rs200231898 and rs201107751 Polymorphisms in the Human RORγT Gene Promoter Region M Ratajewski, M Słomka, K Karaś, M Sobalska-Kwapis, ... Genes 8 (4), 126, 2017 | 5 | 2017 |
RORγT agonists as immune modulators in anticancer therapy. J Pastwińska, I Karwaciak, K Karaś, R Bachorz, M Ratajewski Biochimica et Biophysica Acta (BBA)-Reviews on Cancer, 189021, 2023 | 2 | 2023 |
The application of machine learning methods to the prediction of novel ligands for RORγ/RORγT receptors RA Bachorz, J Pastwińska, D Nowak, K Karaś, I Karwaciak, M Ratajewski Computational and Structural Biotechnology Journal 21, 5491-5505, 2023 | 1 | 2023 |