| Antimicrobial peptides (AMPs) as drug candidates: a patent review (2003–2015) P Kosikowska, A Lesner Expert opinion on therapeutic patents 26 (6), 689-702, 2016 | 182 | 2016 |
| Therapeutic targeting of cathepsin C: from pathophysiology to treatment B Korkmaz, GH Caughey, I Chapple, F Gauthier, J Hirschfeld, DE Jenne, ... Pharmacology & therapeutics 190, 202-236, 2018 | 115 | 2018 |
| Aggregated neutrophil extracellular traps resolve inflammation by proteolysis of cytokines and chemokines and protection from antiproteases J Hahn, C Schauer, C Czegley, L Kling, L Petru, B Schmid, D Weidner, ... The FASEB Journal 33 (1), 1401, 2019 | 110 | 2019 |
| Lung protection by cathepsin C inhibition: A new hope for COVID-19 and ARDS? Miniperspective B Korkmaz, A Lesner, S Marchand-Adam, C Moss, DE Jenne Journal of Medicinal Chemistry 63 (22), 13258-13265, 2020 | 75 | 2020 |
| Fecal serine protease profiling in inflammatory bowel diseases A Jablaoui, A Kriaa, H Mkaouar, N Akermi, S Soussou, M Wysocka, ... Frontiers in cellular and infection microbiology 10, 21, 2020 | 73 | 2020 |
| Neutrophil proteinase 3 and dipeptidyl peptidase I (cathepsin C) as pharmacological targets in granulomatosis with polyangiitis (Wegener granulomatosis) B Korkmaz, A Lesner, S Letast, YK Mahdi, ML Jourdan, S Dallet-Choisy, ... Seminars in immunopathology 35, 411-421, 2013 | 70 | 2013 |
| Myeloperoxidase modulates inflammation in generalized pustular psoriasis and additional rare pustular skin diseases S Haskamp, H Bruns, M Hahn, M Hoffmann, A Gregor, S Löhr, J Hahn, ... The American Journal of Human Genetics 107 (3), 527-538, 2020 | 63 | 2020 |
| Substrate profiling of Zika virus NS 2B‐NS 3 protease N Gruba, JI Rodriguez Martinez, R Grzywa, M Wysocka, M Skoreński, ... FEBS letters 590 (20), 3459-3468, 2016 | 58 | 2016 |
| Sunflower trypsin inhibitor 1 as a molecular scaffold for drug discovery A Lesner, A Legowska, M Wysocka, K Rolka Current pharmaceutical design 17 (38), 4308-4317, 2011 | 58 | 2011 |
| Neutrophilic cathepsin C is maturated by a multistep proteolytic process and secreted by activated cells during inflammatory lung diseases Y Hamon, M Legowska, V Hervé, S Dallet-Choisy, S Marchand-Adam, ... Journal of Biological Chemistry 291 (16), 8486-8499, 2016 | 56 | 2016 |
| Introduction of non-natural amino acid residues into the substrate-specific P1 position of trypsin inhibitor SFTI-1 yields potent chymotrypsin and cathepsin G inhibitors A Łęgowska, D Dębowski, A Lesner, M Wysocka, K Rolka Bioorganic & medicinal chemistry 17 (9), 3302-3307, 2009 | 54 | 2009 |
| Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases C Guarino, Y Hamon, C Croix, AS Lamort, S Dallet-Choisy, ... Biochemical pharmacology 131, 52-67, 2017 | 49 | 2017 |
| Structural and functional analysis of human HtrA3 protease and its subdomains P Glaza, J Osipiuk, T Wenta, D Zurawa-Janicka, M Jarzab, A Lesner, ... PloS one 10 (6), e0131142, 2015 | 48 | 2015 |
| Cathepsin G activity lowers plasma LDL and reduces atherosclerosis J Wang, S Sjöberg, TT Tang, K Öörni, W Wu, C Liu, B Secco, V Tia, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (11 …, 2014 | 44 | 2014 |
| Properties of the HtrA Protease From Bacterium Helicobacter pylori Whose Activity Is Indispensable for Growth Under Stress Conditions U Zarzecka, A Modrak-Wójcik, D Figaj, M Apanowicz, A Lesner, ... Frontiers in Microbiology 10, 961, 2019 | 40 | 2019 |
| New selective peptidyl di (chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases C Guarino, M Legowska, C Epinette, C Kellenberger, S Dallet-Choisy, ... Journal of Biological Chemistry 289 (46), 31777-31791, 2014 | 40 | 2014 |
| Biochemical and structural characterization of SplD protease from Staphylococcus aureus M Zdzalik, M Kalinska, M Wysocka, J Stec-Niemczyk, P Cichon, N Stach, ... PLoS One 8 (10), e76812, 2013 | 40 | 2013 |
| Temperature-induced changes of HtrA2 (Omi) protease activity and structure D Zurawa-Janicka, M Jarzab, A Polit, J Skorko-Glonek, A Lesner, A Gitlin, ... Cell Stress and Chaperones 18 (1), 35-51, 2013 | 38 | 2013 |
| Design of serine proteinase inhibitors by combinatorial chemistry using trypsin inhibitor SFTI‐1 as a starting structure E Zabłotna, A Jaśkiewicz, A Łęgowska, H Miecznikowska, A Lesner, ... Journal of peptide science: an official publication of the European Peptide …, 2007 | 38 | 2007 |
| Substrate specificity and inhibitory study of human airway trypsin-like protease M Wysocka, B Spichalska, A Lesner, M Jaros, K Brzozowski, A Łęgowska, ... Bioorganic & medicinal chemistry 18 (15), 5504-5509, 2010 | 37 | 2010 |
Magdalena WysockaWydział Chemii Uniwersytet GdańskiVerified email at ug.edu.pl
