| Evidence for a new human CYP1A1 regulation pathway involving PPAR-α and 2 PPRE sites E Seree, PH Villard, JM Pascussi, T Pineau, P Maurel, QB Nguyen, ... Gastroenterology 127 (5), 1436-1445, 2004 | 104 | 2004 |
| Effects of Tobacco Smoke on the Gene Expression of theCyp1a, Cyp2b, Cyp2e, andCyp3aSubfamilies in Mouse Liver and Lung: Relation to Single Strand Breaks of DNA PH Villard, EM Seree, JL Re, M De Meo, Y Barra, L Attolini, G Dumenil, ... Toxicology and applied pharmacology 148 (2), 195-204, 1998 | 94 | 1998 |
| Glucuronidation of propofol in microsomal fractions from various tissues and species including humans: effect of different drugs C Le Guellec, B Lacarelle, PH Villard, H Point, J Catalin, A Durand Anesthesia & Analgesia 81 (4), 855-861, 1995 | 94 | 1995 |
| Polycyclic aromatic hydrocarbons potentiate high-fat diet effects on intestinal inflammation A Khalil, PH Villard, MA Dao, R Burcelin, S Champion, F Fouchier, ... Toxicology letters 196 (3), 161-167, 2010 | 83 | 2010 |
| Effect of cigarette smoke on UDP‐glucuronosyltransferase activity and cytochrome P450 content in liver, lung and kidney microsomes in mice PH Villard, R Hcrber, EM Sérée, L Attolini, J Magdalou, B Lacarelle Pharmacology & toxicology 82 (2), 74-79, 1998 | 83 | 1998 |
| Oxidative metabolism of bupivacaine into pipecolylxylidine in humans is mainly catalyzed by CYP3A M Gantenbein, L Attolini, B Bruguerolle, PH Villard, F Puyoou, A Durand, ... Drug metabolism and disposition 28 (4), 383-385, 2000 | 79 | 2000 |
| Effect of cigarette smoke on hepatic and pulmonary cytochromes P450 in mouse: evidence for CYP2E1 induction in lung PH Villard, E Seree, B Lacarelle, MC Therenefenoglio, Y Barra, L Attolini, ... Biochemical and biophysical research communications 202 (3), 1731-1737, 1994 | 70 | 1994 |
| Modulation of MDR1 and CYP3A expression by dexamethasone: evidence for an inverse regulation in adrenals E Seree, PH Villard, A Hever, N Guigal, F Puyoou, B Charvet, ... Biochemical and biophysical research communications 252 (2), 392-395, 1998 | 67 | 1998 |
| Increase of CYP1B1 transcription in human keratinocytes and HaCaT cells after UV-B exposure PH Villard, E Sampol, JL Elkaim, F Puyoou, D Casanova, E Sérée, ... Toxicology and applied pharmacology 178 (3), 137-143, 2002 | 60 | 2002 |
| Retinoids repress Ah receptor CYP1A1 induction pathway through the SMRT corepressor F Fallone, PH Villard, E Sérée, O Rimet, QB Nguyen, V Bourgarel-Rey, ... Biochemical and Biophysical Research Communications 322 (2), 551-556, 2004 | 57 | 2004 |
| PPARα activation potentiates AhR-induced CYP1A1 expression F Fallone, PH Villard, L Decome, E Sérée, M De Meo, C Chacon, ... Toxicology 216 (2-3), 122-128, 2005 | 47 | 2005 |
| PPARα activation potentiates AhR-induced CYP1A1 expression F Fallone, PH Villard, L Decome, E Sérée, M De Meo, C Chacon, ... Toxicology 216 (2-3), 122-128, 2005 | 47 | 2005 |
| High inducibility of mouse renal CYP2E1 gene by tobacco smoke and its possible effect on DNA single strand breaks EM Seree, PH Villard, JL Re, M De Meo, B Lacarelle, L Attolini, G Dumenil, ... Biochemical and biophysical research communications 219 (2), 429-434, 1996 | 46 | 1996 |
| PPARα transcriptionally induces AhR expression in Caco-2, but represses AhR pro-inflammatory effects PH Villard, S Caverni, A Baanannou, A Khalil, PG Martin, C Penel, ... Biochemical and biophysical research communications 364 (4), 896-901, 2007 | 41 | 2007 |
| CYP1A1 induction in the colon by serum: involvement of the PPARα pathway and evidence for a new specific human PPREα site PH Villard, F Barlesi, M Armand, TMA Dao, JM Pascussi, F Fouchier, ... PloS one 6 (1), e14629, 2011 | 34 | 2011 |
| Panax vietnamensis protects mice against carbon tetrachloride-induced hepatotoxicity without any modification of CYP2E1 gene expression TD Nguyen, PH Villard, A Barlatier, AE Elsisi, E Jouve, NM Duc, C Sauze, ... Planta medica 66 (08), 714-719, 2000 | 29 | 2000 |
| The transcriptional effects of PCB118 and PCB153 on the liver, adipose tissue, muscle and colon of mice: highlighting of Glut4 and Lipin1 as main target genes for PCB induced … A Mesnier, S Champion, L Louis, C Sauzet, P May, H Portugal, ... PLoS One 10 (6), e0128847, 2015 | 26 | 2015 |
| Abbott PKS system: a new version for applied pharmacokinetics including Bayesian estimation B Lacarelle, P Pisano, T Gauthier, PH Villard, F Guder, J Catalin, ... International journal of bio-medical computing 36 (1-2), 127-130, 1994 | 25 | 1994 |
| Dietary lipids affect human ethanol-inducible CYP2E1 gene expression in vivo in mononuclear cells P Boucher, E Seree, C Vidon, AC de Souza, PH Villard, R Chambon, ... Life sciences 67 (11), 1307-1316, 2000 | 20 | 2000 |
| Evidence for a tissue-specific induction of cutaneous CYP2E1 by dexamethasone E Sampol, A Mirrione, PH Villard, P Piccerelle, H Scoma, P Berbis, ... Biochemical and biophysical research communications 235 (3), 557-561, 1997 | 18 | 1997 |
