| Analysis of a 10-ns molecular dynamics simulation of mouse acetylcholinesterase K Tai, T Shen, U Börjesson, M Philippopoulos, JA McCammon Biophysical journal 81 (2), 715-724, 2001 | 208 | 2001 |
| Explicit-solvent molecular dynamics simulation at constant Methodology and application to small amines U Börjesson, PH Hünenberger The Journal of Chemical Physics 114 (22), 9706-9719, 2001 | 147 | 2001 |
| pH-dependent stability of a decalysine α-helix studied by explicit-solvent molecular dynamics simulations at constant pH U Börjesson, PH Hünenberger The Journal of Physical Chemistry B 108 (35), 13551-13559, 2004 | 69 | 2004 |
| Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides RH Clare, C Bardelle, P Harper, WD Hong, U Börjesson, KL Johnston, ... Nature communications 10 (1), 11, 2019 | 54 | 2019 |
| Electrostatic interactions in biomolecular systems PH Hünenberger, U Börjesson, RD Lins Chimia 55 (10), 861-861, 2001 | 28 | 2001 |
| Chemogenetics defines a short-chain fatty acid receptor gut–brain axis N Barki, D Bolognini, U Börjesson, L Jenkins, J Riddell, DI Hughes, ... Elife 11, e73777, 2022 | 24 | 2022 |
| Discovery of AZD8154, a dual PI3Kγδ inhibitor for the treatment of asthma MWD Perry, K Bjorhall, P Bold, M Brulls, U Borjesson, J Carlsson, ... Journal of Medicinal Chemistry 64 (12), 8053-8075, 2021 | 24 | 2021 |
| ProSAR: a new methodology for combinatorial library design H Chen, U Borjesson, O Engkvist, T Kogej, MA Svensson, N Blomberg, ... Journal of chemical information and modeling 49 (3), 603-614, 2009 | 20 | 2009 |
| Fragment-Based Design of a Potent MAT2a Inhibitor and in Vivo Evaluation in an MTAP Null Xenograft Model C De Fusco, M Schimpl, U Börjesson, T Cheung, I Collie, L Evans, ... Journal of Medicinal Chemistry 64 (10), 6814-6826, 2021 | 19 | 2021 |
| Phenotypic high-throughput screening platform identifies novel chemotypes for necroptosis inhibition. H Brito, V Marques, MB Afonso, DG Brown, U Börjesson, N Selmi, ... Cell Death Discovery 6 (Aricle number: 6(2020)), 2020 | 16 | 2020 |
| Structural basis for targeting the folded P-loop conformation of c-MET GW Collie, IN Michaelides, K Embrey, CJ Stubbs, U Börjesson, IL Dale, ... ACS Medicinal Chemistry Letters 12 (1), 162-167, 2020 | 12 | 2020 |
| Effect of mutations involving charged residues on the stability of staphylococcal nuclease: a continuum electrostatics study U Börjesson, PH Hünenberger Protein engineering 16 (11), 831-840, 2003 | 11 | 2003 |
| Fragment-based discovery of novel allosteric MEK1 binders P Di Fruscia, F Edfeldt, I Shamovsky, GW Collie, A Aagaard, L Barlind, ... ACS Medicinal Chemistry Letters 12 (2), 302-308, 2021 | 9 | 2021 |
| Fragment screening at AstraZeneca: developing the next generation biophysics fragment set SCC Lucas, U Börjesson, MJ Bostock, J Cuff, F Edfeldt, KJ Embrey, ... RSC Medicinal Chemistry 13 (9), 1052-1057, 2022 | 8 | 2022 |
| Discovery and optimization of the first ATP competitive type-III c-MET inhibitor IN Michaelides, GW Collie, U Börjesson, C Vasalou, O Alkhatib, ... Journal of Medicinal Chemistry 66 (13), 8782-8807, 2023 | 5 | 2023 |
| Discovery of a selective c-MET inhibitor with a novel binding mode GW Collie, L Barlind, S Bazzaz, U Börjesson, IL Dale, JS Disch, ... Bioorganic & Medicinal Chemistry Letters 75, 128948, 2022 | 5 | 2022 |
| 5-[2-(pyridin-2-ylamino)-1, 3-thiazol-5-yl]-2, 3-dihydro-1 h-isoindol-1-one derivatives and their use as dual inhibitors of phosphatidylinositol 3-kinase delta & gamma M Perry, K Karabelas, M Mogemark, P Bold, C Tyrchan, A Nikitidis, ... | 4 | 2018 |
| Surprising lipophilicity observations identify unexpected conformational effects MWD Perry, U Börjesson, A Nikitidis, C Tyrchan Bioorganic & Medicinal Chemistry Letters 69, 128786, 2022 | 1 | 2022 |
| Chemogenetic analysis of how receptors for short chain fatty acids regulate the gut-brain axis N Barki, D Bolognini, U Börjesson, L Jenkins, J Riddell, DI Hughes, ... bioRxiv, 2020.01. 11.902726, 2020 | 1 | 2020 |
| Chemogenomics in Drug Discovery. Methods and Principles in Medicinal Chemistry, Vol. 22. Edited by Hugo Kubinyi and Gerhard Müller. U Börjesson Angewandte Chemie International Edition 44 (19), 2832-2832, 2005 | 1 | 2005 |
