SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function NL Price, AP Gomes, AJY Ling, FV Duarte, A Martin-Montalvo, BJ North, ... Cell metabolism 15 (5), 675-690, 2012 | 1608 | 2012 |
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging P Oberdoerffer, S Michan, M McVay, R Mostoslavsky, J Vann, SK Park, ... Cell 135 (5), 907-918, 2008 | 965 | 2008 |
Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy AV Hafner, J Dai, AP Gomes, CY Xiao, CM Palmeira, A Rosenzweig, ... Aging (Albany NY) 2 (12), 914, 2010 | 576 | 2010 |
SIRT 2 induces the checkpoint kinase BubR1 to increase lifespan BJ North, MA Rosenberg, KB Jeganathan, AV Hafner, S Michan, J Dai, ... The EMBO journal 33 (13), 1438-1453, 2014 | 234 | 2014 |
Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system R Al‐Shawi, A Hafner, J Olson, S Chun, S Raza, C Thrasivoulou, ... European Journal of Neuroscience 27 (8), 2103-2114, 2008 | 155 | 2008 |
ProNGF, sortilin, and age‐related neurodegeneration R AL‐SHAWI, A Hafner, S Chun, S Raza, K Crutcher, C Thrasivoulou, ... Annals of the New York Academy of Sciences 1119 (1), 208-215, 2007 | 98 | 2007 |
Prolyl isomerase Pin1 regulates neuronal differentiation via β-catenin K Nakamura, I Kosugi, DY Lee, A Hafner, DA Sinclair, A Ryo, KP Lu Molecular and cellular biology 32 (15), 2966-2978, 2012 | 76 | 2012 |
Reconstitution of gene expression from a regulatory‐protein‐deficient hepatitis B virus genome by cell‐permeable HBx protein A Hafner, B Brandenburg, E Hildt EMBO reports 4 (8), 767-773, 2003 | 47 | 2003 |
A mutation in Tubb2b, a human polymicrogyria gene, leads to lethality and abnormal cortical development in the mouse RW Stottmann, M Donlin, A Hafner, A Bernard, DA Sinclair, DR Beier Human molecular genetics 22 (20), 4053-4063, 2013 | 33 | 2013 |
DNA damage-induced alterations in chromatin contribute to genomic integrity and age-related changes in gene expression P Oberdoerffer, S Michan, M McVay, R Mostoslavsky, J Vann, SK Park, ... Cell 135 (5), 907, 2008 | 19 | 2008 |
Detection and modulation of cytochrome c acetylation AV Hafner, DA Sinclair US Patent App. 13/125,405, 2012 | 7 | 2012 |
Detection and modulation of cytochrome c acetylation AV Hafner, DA Sinclair US Patent App. 14/598,813, 2015 | 2 | 2015 |
Role of the Mitochondrial NAD+-dependent Deacetylase SIRT3 in Age-dependent Diseases of Postmitotic Tissues AV Hafner | | 2012 |
Does Declining Mitochondrial NAD+ and Unscheduled Opening of Mitochondrial Transition Pore Promote Mammalian Aging? D Sinclair, AV Hafner, A Gomes, J Liang, Y Cen, I Lanza, S Nair, A Sauve, ... Blood, The Journal of the American Society of Hematology 116 (21), SCI-3-SCI-3, 2010 | | 2010 |
Does Declining Mitochondrial NAD plus and Unscheduled Opening of Mitochondrial Transition Pore Promote Mammalian Aging? D Sinclair, AV Hafner, A Gomes, J Liang, Y Cen, I Lanza, S Nair, A Sauve, ... BLOOD 116 (21), 1755-1755, 2010 | | 2010 |
Sirtuins as modulators of metabolism and longevity A Hafner, A Tinel, J Dai, T Rosenzweig, R DeCabo, B Yankner, ... DIABETES OBESITY & METABOLISM 12, 9-9, 2010 | | 2010 |