Katherine Lansu
Katherine Lansu
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Cited by
Cited by
PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome
WK Kroeze, MF Sassano, XP Huang, K Lansu, JD McCorvy, PM Giguère, ...
Nature structural & molecular biology 22 (5), 362-369, 2015
Crystal structure of an LSD-bound human serotonin receptor
D Wacker, S Wang, JD McCorvy, RM Betz, AJ Venkatakrishnan, A Levit, ...
Cell 168 (3), 377-389. e12, 2017
In silico design of novel probes for the atypical opioid receptor MRGPRX2
K Lansu, J Karpiak, J Liu, XP Huang, JD McCorvy, WK Kroeze, T Che, ...
Nature chemical biology 13 (5), 529-536, 2017
5-HT2C receptor structures reveal the structural basis of GPCR polypharmacology
Y Peng, JD McCorvy, K Harpsøe, K Lansu, S Yuan, P Popov, L Qu, M Pu, ...
Cell 172 (4), 719-730. e14, 2018
Structural determinants of 5-HT2B receptor activation and biased agonism
JD McCorvy, D Wacker, S Wang, B Agegnehu, J Liu, K Lansu, AR Tribo, ...
Nature structural & molecular biology 25 (9), 787-796, 2018
Structure, function and pharmacology of human itch GPCRs
C Cao, HJ Kang, I Singh, H Chen, C Zhang, W Ye, BW Hayes, J Liu, ...
Nature 600 (7887), 170-175, 2021
VEGAS as a platform for facile directed evolution in mammalian cells
JG English, RHJ Olsen, K Lansu, M Patel, K White, AS Cockrell, D Singh, ...
Cell 178 (3), 748-761. e17, 2019
Potassium channel activation inhibits proliferation of breast cancer cells by activating a senescence program
K Lansu, S Gentile
Cell death & disease 4 (6), e652-e652, 2013
Activation of hERG3 channel stimulates autophagy and promotes cellular senescence in melanoma
M Perez-Neut, L Haar, V Rao, S Santha, K Lansu, B Rana, WK Jones, ...
Oncotarget 7 (16), 21991, 2016
An African-specific haplotype in MRGPRX4 is associated with menthol cigarette smoking
J Kozlitina, D Risso, K Lansu, RHJ Olsen, E Sainz, D Luiselli, A Barik, ...
PLoS genetics 15 (2), e1007916, 2019
Mast cell degranulation and fibroblast activation in the morphine-induced spinal mass: role of mas-related G protein-coupled receptor signaling
TL Yaksh, KA Eddinger, S Kokubu, Z Wang, A DiNardo, R Ramachandran, ...
Anesthesiology 131 (1), 132-147, 2019
Long QT2 mutation on the Kv11. 1 ion channel inhibits current activity by ablating a protein kinase Cα consensus site
AJ Donovan, K Lansu, JG Williams, MF Denning, S Gentile
Molecular Pharmacology 82 (3), 428-437, 2012
Exploring and avoiding morphine-induced spinal masses
T Yaksh, K Eddinger, S Kokubu, Z Wang, A DiNardo, R Ramachandran, ...
Long QT2 Mutation on the Kv11. 1 Ion Channel Inhibits Current Activity by Ablating a Protein Kinase C alpha Consensus Site (vol 82, pg 428, 2012)
AJ Donovan, K Lansu, JG Williams, MF Denning, S Gentile
MOLECULAR PHARMACOLOGY 96 (3), 377-377, 2019
Structural basis of G protein couple receptor polypharmacology
Y Peng, JD McCorvy, K Harpsoe, K Lansu, S Yuan, P Popov, L Qu, M Pu, ...
Ligand Discovery and Functional Characterization of MRGPRX Family Orphan GPCRs
K Lansu
The University of North Carolina at Chapel Hill, 2017
hERG1 agonist NS1643 inhibits proliferation of ER‐neg breast cancer cells by activating a senescence program
S Gentile, K Lansu, GH Ha, EK Breuer
The FASEB Journal 27, 913.34-913.34, 2013
Sex (y) hormone a‐go‐go: Estrogen–dependent stimulation of hERG potassium channel via G Protein Estrogen Receptor (GPER)
S Gentile, K Lansu
The FASEB Journal 27, 913.33-913.33, 2013
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