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Nicholas Nickerson
Nicholas Nickerson
Researcher, Genentech
Verified email at gene.com - Homepage
Title
Cited by
Cited by
Year
Monoclonal antibody targeting the β-barrel assembly machine of Escherichia coli is bactericidal
KM Storek, MR Auerbach, H Shi, NK Garcia, D Sun, NN Nickerson, R Vij, ...
Proceedings of the National Academy of Sciences 115 (14), 3692-3697, 2018
1582018
Sorting of an integral outer membrane protein via the lipoprotein‐specific Lol pathway and a dedicated lipoprotein pilotin
S Collin, I Guilvout, NN Nickerson, AP Pugsley
Molecular microbiology 80 (3), 655-665, 2011
722011
Structure of the essential inner membrane lipopolysaccharide–PbgA complex
T Clairfeuille, KR Buchholz, Q Li, E Verschueren, P Liu, D Sangaraju, ...
Nature 584 (7821), 479-483, 2020
712020
Activation of the SspA serine protease zymogen of Staphylococcus aureus proceeds through unique variations of a trypsinogen-like mechanism and is dependent on both …
NN Nickerson, L Prasad, L Jacob, LT Delbaere, MJ McGavin
Journal of biological chemistry 282 (47), 34129-34138, 2007
672007
A novel inhibitor of the LolCDE ABC transporter essential for lipoprotein trafficking in Gram-negative bacteria
NN Nickerson, CC Jao, Y Xu, J Quinn, E Skippington, MK Alexander, ...
Antimicrobial agents and chemotherapy 62 (4), 10.1128/aac. 02151-17, 2018
632018
Disrupting gram-negative bacterial outer membrane biosynthesis through inhibition of the lipopolysaccharide transporter MsbA
MK Alexander, A Miu, A Oh, M Reichelt, H Ho, C Chalouni, S Labadie, ...
Antimicrobial Agents and Chemotherapy 62 (11), 10.1128/aac. 01142-18, 2018
602018
Rapid autocatalytic activation of the M4 metalloprotease aureolysin is controlled by a conserved N‐terminal fungalysin‐thermolysin‐propeptide domain
NN Nickerson, V Joag, MJ McGavin
Molecular microbiology 69 (6), 1530-1543, 2008
592008
Evolutionary blueprint for host- and niche-adaptation in Staphylococcus aureus clonal complex CC30
MJ McGavin, B Arsic, NN Nickerson
Frontiers in cellular and infection microbiology 2, 48, 2012
522012
Trapped translocation intermediates establish the route for export of capsular polysaccharides across Escherichia coli outer membranes
NN Nickerson, IL Mainprize, L Hampton, ML Jones, JH Naismith, ...
Proceedings of the National Academy of Sciences 111 (22), 8203-8208, 2014
502014
Outer membrane targeting of Pseudomonas aeruginosa proteins shows variable dependence on the components of Bam and Lol machineries
HH Hoang, NN Nickerson, VT Lee, A Kazimirova, M Chami, AP Pugsley, ...
MBio 2 (6), 10.1128/mbio. 00246-11, 2011
472011
Pilotin–secretin recognition in the type II secretion system of Klebsiella oxytoca
T Tosi, NN Nickerson, L Mollica, MR Jensen, M Blackledge, B Baron, ...
Molecular microbiology 82 (6), 1422-1432, 2011
412011
Outer Membrane Targeting of Secretin PulD Protein Relies on Disordered Domain Recognition by a Dedicated Chaperone*♦
NN Nickerson, T Tosi, A Dessen, B Baron, B Raynal, P England, ...
Journal of Biological Chemistry 286 (45), 38833-38843, 2011
412011
Comparison of Staphopain A (ScpA) and B (SspB) precursor activation mechanisms reveals unique secretion kinetics of proSspB (Staphopain B), and a different interaction with its …
N Nickerson, J Ip, DT Passos, MJ McGavin
Molecular microbiology 75 (1), 161-177, 2010
412010
Multimerization-defective variants of dodecameric secretin PulD
I Guilvout, NN Nickerson, M Chami, AP Pugsley
Research in microbiology 162 (2), 180-190, 2011
362011
Peptidoglycan association of murein lipoprotein is required for KpsD-dependent group 2 capsular polysaccharide expression and serum resistance in a uropathogenic Escherichia …
J Diao, C Bouwman, D Yan, J Kang, AK Katakam, P Liu, H Pantua, ...
MBio 8 (3), 10.1128/mbio. 00603-17, 2017
342017
Structural and functional variation in outer membrane polysaccharide export (OPX) proteins from the two major capsule assembly pathways present in Escherichia coli
C Sande, C Bouwman, E Kell, NN Nickerson, SB Kapadia, C Whitfield
Journal of Bacteriology 201 (14), 10.1128/jb. 00213-19, 2019
172019
A single amino acid substitution changes the self-assembly status of a type IV piliation secretin
NN Nickerson, SS Abby, EPC Rocha, M Chami, AP Pugsley
Journal of bacteriology 194 (18), 4951-4958, 2012
172012
Inhibition of Escherichia coli lipoprotein diacylglyceryl transferase is insensitive to resistance caused by deletion of Braun’s lipoprotein
J Diao, R Komura, T Sano, H Pantua, KM Storek, H Inaba, H Ogawa, ...
Journal of Bacteriology 203 (13), 10.1128/jb. 00149-21, 2021
162021
Lipids assist the membrane insertion of a BAM-independent outer membrane protein
GHM Huysmans, I Guilvout, M Chami, NN Nickerson, AP Pugsley
Scientific reports 5 (1), 15068, 2015
152015
Genetic, biochemical, and structural analyses of bacterial surface polysaccharides
CA Cooper, IL Mainprize, NN Nickerson
Prokaryotic Systems Biology, 295-315, 2015
62015
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