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Panagiotis Fotakis
Panagiotis Fotakis
Dren Bio
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Tytuł
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Cholesterol efflux pathways suppress inflammasome activation, NETosis, and atherogenesis
M Westerterp, P Fotakis, M Ouimet, AE Bochem, H Zhang, MM Molusky, ...
Circulation 138 (9), 898-912, 2018
2582018
Cholesterol accumulation in dendritic cells links the inflammasome to acquired immunity
M Westerterp, EL Gautier, A Ganda, MM Molusky, W Wang, P Fotakis, ...
Cell metabolism 25 (6), 1294-1304. e6, 2017
1832017
HDL biogenesis, remodeling, and catabolism
VI Zannis, P Fotakis, G Koukos, D Kardassis, C Ehnholm, M Jauhiainen, ...
Handb Exp Pharmacol 224, 53-111, 2015
1362015
Deficiency of ATP-binding cassette transporters A1 and G1 in endothelial cells accelerates atherosclerosis in mice
M Westerterp, K Tsuchiya, IW Tattersall, P Fotakis, AE Bochem, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 36 (7), 1328-1337, 2016
1102016
Anti-inflammatory effects of HDL (high-density lipoprotein) in macrophages predominate over proinflammatory effects in atherosclerotic plaques
P Fotakis, V Kothari, DG Thomas, M Westerterp, MM Molusky, E Altin, ...
Arteriosclerosis, thrombosis, and vascular biology 39 (12), e253-e272, 2019
1012019
LXR suppresses inflammatory gene expression and neutrophil migration through cis-repression and cholesterol efflux
DG Thomas, AC Doran, P Fotakis, M Westerterp, P Antonson, H Jiang, ...
Cell reports 25 (13), 3774-3785. e4, 2018
802018
ApoA-IV promotes the biogenesis of apoA-IV-containing HDL particles with the participation of ABCA1 and LCAT [S]
A Duka, P Fotakis, D Georgiadou, A Kateifides, K Tzavlaki, ...
Journal of lipid research 54 (1), 107-115, 2013
472013
HDL-apoA-I induces the expression of angiopoietin like 4 (ANGPTL4) in endothelial cells via a PI3K/AKT/FOXO1 signaling pathway
D Theofilatos, P Fotakis, E Valanti, D Sanoudou, V Zannis, D Kardassis
Metabolism 87, 36-47, 2018
272018
Reconstituted HDL-apoE3 promotes endothelial cell migration through ID1 and its downstream kinases ERK1/2, AKT and p38 MAPK
EK Valanti, K Dalakoura-Karagkouni, P Fotakis, E Vafiadaki, ...
Metabolism 127, 154954, 2022
172022
The effect of natural LCAT mutations on the biogenesis of HDL
P Fotakis, JA Kuivenhoven, E Dafnis, D Kardassis, VI Zannis
Biochemistry 54 (21), 3348-3359, 2015
172015
Role of the hydrophobic and charged residues in the 218–226 region of apoA-I in the biogenesis of HDL1 [S]
P Fotakis, AK Kateifides, C Gkolfinopoulou, D Georgiadou, M Beck, ...
Journal of lipid research 54 (12), 3281-3292, 2013
172013
Cholesterol accumulation in macrophages drives NETosis in atherosclerotic plaques via IL-1β secretion
M Yalcinkaya, P Fotakis, W Liu, K Endo-Umeda, H Dou, S Abramowicz, ...
Cardiovascular Research 119 (4), 969-981, 2023
162023
Significance of the hydrophobic residues 225–230 of apoA-I for the biogenesis of HDL1 [S]
P Fotakis, I Tiniakou, AK Kateifides, C Gkolfinopoulou, A Chroni, ...
Journal of lipid research 54 (12), 3293-3302, 2013
162013
Natural human apoA-I mutations L141RPisa and L159RFIN alter HDL structure and functionality and promote atherosclerosis development in mice
I Tiniakou, Z Kanaki, S Georgopoulos, A Chroni, M Van Eck, P Fotakis, ...
Atherosclerosis 243 (1), 77-85, 2015
142015
Pleiotropic functions of HDL lead to protection from atherosclerosis and other diseases
V Zannis, A Kateifides, P Fotakis, E Zanni, D Kardassis
Dyslipidemia-From Prevention to Treatment, 173-96, 2012
122012
Role of apolipoproteins, ABCA1 and LCAT in the biogenesis of normal and aberrant high density lipoproteins
VI Zannis, S Su, P Fotakis
Journal of Biomedical Research 31 (6), 471, 2017
102017
TTC39B destabilizes retinoblastoma protein promoting hepatic lipogenesis in a sex-specific fashion
J Hsieh, MM Molusky, KM McCabe, P Fotakis, T Xiao, L Tascau, ...
Journal of hepatology 76 (2), 383-393, 2022
42022
apoE3 [K146N/R147W] acts as a dominant negative apoE form that prevents remnant clearance and inhibits the biogenesis of HDL [S]
P Fotakis, A Vezeridis, I Dafnis, A Chroni, D Kardassis, VI Zannis
Journal of Lipid Research 55 (7), 1310-1323, 2014
42014
Response by Fotakis et al to Letter Regarding Article,“Anti-inflammatory effects of HDL (High-Density Lipoprotein) in macrophages predominate over proinflammatory effects in …
P Fotakis, V Kothari, KE Bornfeldt, AR Tall
Arteriosclerosis, thrombosis, and vascular biology 40 (2), e33-e34, 2020
22020
Anti-inflammatory effects of HDL in macrophages predominate over pro-inflammatory effects in atherosclerotic plaques
P Fotakis, V Kothari, DG Thomas, M Westerterp, MM Molusky, E Altin, ...
Arteriosclerosis, thrombosis, and vascular biology 39 (12), e253, 2019
12019
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