Human gut microbes impact host serum metabolome and insulin sensitivity HK Pedersen, V Gudmundsdottir, HB Nielsen, T Hyotylainen, T Nielsen, ... Nature 535 (7612), 376-381, 2016 | 1958 | 2016 |
The dynamics of the human infant gut microbiome in development and in progression toward type 1 diabetes AD Kostic, D Gevers, H Siljander, T Vatanen, T Hyötyläinen, ... Cell host & microbe 17 (2), 260-273, 2015 | 1266 | 2015 |
Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes M Oresic, S Simell, M Sysi-Aho, K Nanto-Salonen, T Seppanen-Laakso, ... The Journal of experimental medicine 205 (13), 2975-2984, 2008 | 517 | 2008 |
Bioprocessing of wheat bran improves in vitro bioaccessibility and colonic metabolism of phenolic compounds NM Anson, E Selinheimo, R Havenaar, AM Aura, I Mattila, P Lehtinen, ... Journal of agricultural and food chemistry 57 (14), 6148-6155, 2009 | 316 | 2009 |
Metabolome in progression to Alzheimer's disease M Ore¹iè, T Hyötyläinen, SK Herukka, M Sysi-Aho, I Mattila, ... Translational psychiatry 1 (12), e57-e57, 2011 | 297 | 2011 |
Bioprocessing of wheat bran in whole wheat bread increases the bioavailability of phenolic acids in men and exerts antiinflammatory effects ex vivo NM Anson, AM Aura, E Selinheimo, I Mattila, K Poutanen, ... The Journal of nutrition 141 (1), 137-143, 2011 | 241 | 2011 |
Ketogenic diet slows down mitochondrial myopathy progression in mice S Ahola-Erkkilä, CJ Carroll, K Peltola-Mjösund, V Tulkki, I Mattila, ... Human molecular genetics 19 (10), 1974-1984, 2010 | 223 | 2010 |
Data analysis tool for comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry S Castillo, I Mattila, J Miettinen, M Oresic, T Hyötyläinen Analytical Chemistry 83 (8), 3058-3067, 2011 | 201 | 2011 |
Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids M Ore¹iè, T Hyötyläinen, A Kotronen, P Gopalacharyulu, H Nygren, ... Diabetologia 56, 2266-2274, 2013 | 174 | 2013 |
Metabolome in schizophrenia and other psychotic disorders: a general population-based study M Ore¹iè, J Tang, T Seppänen-Laakso, I Mattila, SE Saarni, SI Saarni, ... Genome medicine 3, 1-14, 2011 | 173 | 2011 |
Integrated multilaboratory systems biology reveals differences in protein metabolism between two reference yeast strains AB Canelas, N Harrison, A Fazio, J Zhang, JP Pitkänen, J Van Den Brink, ... Nature communications 1 (1), 145, 2010 | 136 | 2010 |
Formation of phenolic microbial metabolites and short-chain fatty acids from rye, wheat, and oat bran and their fractions in the metabolical in vitro colon model E Nordlund, AM Aura, I Mattila, T Kosso, X Rouau, K Poutanen Journal of agricultural and food chemistry 60 (33), 8134-8145, 2012 | 134 | 2012 |
Factors affecting the conversion of apple polyphenols to phenolic acids and fruit matrix to short-chain fatty acids by human faecal microbiota in vitro S Bazzocco, I Mattila, S Guyot, CMGC Renard, AM Aura European Journal of Nutrition 47, 442-452, 2008 | 130 | 2008 |
Genome-scale study reveals reduced metabolic adaptability in patients with non-alcoholic fatty liver disease T Hyötyläinen, L Jerby, EM Petäjä, I Mattila, S Jäntti, P Auvinen, ... Nature communications 7 (1), 8994, 2016 | 121 | 2016 |
Postprandial differences in the plasma metabolome of healthy Finnish subjects after intake of a sourdough fermented endosperm rye bread versus white wheat bread I Bondia-Pons, E Nordlund, I Mattila, K Katina, AM Aura, M Kolehmainen, ... Nutrition journal 10, 1-10, 2011 | 105 | 2011 |
Metabolic regulation in progression to autoimmune diabetes M Sysi-Aho, A Ermolov, PV Gopalacharyulu, A Tripathi, ... PLoS Computational Biology 7 (10), e1002257, 2011 | 104 | 2011 |
Human serum metabolites associate with severity and patient outcomes in traumatic brain injury M Ore¹iè, JP Posti, MH Kamstrup-Nielsen, RSK Takala, HF Lingsma, ... EBioMedicine 12, 118-126, 2016 | 103 | 2016 |
Microbial metabolism of catechin stereoisomers by human faecal microbiota: comparison of targeted analysis and a non-targeted metabolomics method AM Aura, I Mattila, T Seppänen-Laakso, J Miettinen, ... Phytochemistry Letters 1 (1), 18-22, 2008 | 84 | 2008 |
Characterization of microbial metabolism of Syrah grape products in an in vitro colon model using targeted and non-targeted analytical approaches AM Aura, I Mattila, T Hyötyläinen, P Gopalacharyulu, V Cheynier, ... European journal of nutrition 52, 833-846, 2013 | 79 | 2013 |
Drug metabolome of the simvastatin formed by human intestinal microbiota in vitro AM Aura, I Mattila, T Hyötyläinen, P Gopalacharyulu, C Bounsaythip, ... Molecular BioSystems 7 (2), 437-446, 2011 | 64 | 2011 |