Lactate limits T cell proliferation via the NAD (H) redox state WJ Quinn, J Jiao, T TeSlaa, J Stadanlick, Z Wang, L Wang, T Akimova, ... Cell reports 33 (11), 2020 | 246 | 2020 |
Activation of p38 mitogen-activated protein kinase by PYK2/related adhesion focal tyrosine kinase-dependent mechanism P Pandey, S Avraham, S Kumar, A Nakazawa, A Place, L Ghanem, ... Journal of Biological Chemistry 274 (15), 10140-10144, 1999 | 155 | 1999 |
Specific proteolysis of the kinase protein kinase C-related kinase 2 by caspase-3 during apoptosis: Identification by a novel, small pool expression cloning strategy VL Cryns, Y Byun, A Rana, H Mellor, KD Lustig, L Ghanem, PJ Parker, ... Journal of Biological Chemistry 272 (47), 29449-29453, 1997 | 132 | 1997 |
Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage S Kharbanda, P Pandey, T Yamauchi, S Kumar, M Kaneki, V Kumar, ... Molecular and cellular biology, 2000 | 118 | 2000 |
The poly (C) binding protein Pcbp2 and its retrotransposed derivative Pcbp1 are independently essential to mouse development LR Ghanem, A Kromer, IM Silverman, P Chatterji, E Traxler, ... Molecular and cellular biology, 2016 | 81 | 2016 |
Integrative analysis reveals RNA G-quadruplexes in UTRs are selectively constrained and enriched for functional associations DSM Lee, LR Ghanem, Y Barash Nature communications 11 (1), 527, 2020 | 75 | 2020 |
The pediatric cell atlas: defining the growth phase of human development at single-cell resolution DM Taylor, BJ Aronow, K Tan, K Bernt, N Salomonis, CS Greene, ... Developmental cell 49 (1), 10-29, 2019 | 69 | 2019 |
Disrupting upstream translation in mRNAs is associated with human disease DSM Lee, J Park, A Kromer, A Baras, DJ Rader, MD Ritchie, LR Ghanem, ... Nature Communications 12 (1), 1515, 2021 | 66 | 2021 |
p21Waf1/Cip1 Deficiency Stimulates Centriole Overduplication A Duensing, L Ghanem, RA Steinman, Y Liu, S Duensing Cell Cycle 5 (24), 2899-2902, 2006 | 45 | 2006 |
A proapoptotic function of p21 in differentiating granulocytes L Ghanem, R Steinman Leukemia research 29 (11), 1315-1323, 2005 | 40 | 2005 |
Using computer vision to improve endoscopic disease quantification in therapeutic clinical trials of ulcerative colitis RW Stidham, L Cai, S Cheng, F Rajaei, T Hiatt, E Wittrup, MD Rice, ... Gastroenterology 166 (1), 155-167. e2, 2024 | 24 | 2024 |
Variant-to-gene-mapping analyses reveal a role for the hypothalamus in genetic susceptibility to inflammatory bowel disease C Lasconi, MC Pahl, DL Cousminer, CA Doege, A Chesi, KM Hodge, ... Cellular and Molecular Gastroenterology and Hepatology 11 (3), 667-682, 2021 | 23 | 2021 |
Poly (C)-binding protein Pcbp2 enables differentiation of definitive erythropoiesis by directing functional splicing of the Runx1 transcript LR Ghanem, A Kromer, IM Silverman, X Ji, M Gazzara, N Nguyen, ... Molecular and cellular biology 38 (16), e00175-18, 2018 | 20 | 2018 |
Specific enrichment of the RNA-binding proteins PCBP1 and PCBP2 in chief cells of the murine gastric mucosa LR Ghanem, P Chatterji, SA Liebhaber Gene Expression Patterns 14 (2), 78-87, 2014 | 18 | 2014 |
p21Waf1 inhibits granulocytic differentiation of 32Dcl3 cells L Ghanem, RA Steinman Leukemia research 30 (10), 1285-1292, 2006 | 18 | 2006 |
Automatic estimation of ulcerative colitis severity from endoscopy videos using ordinal multi-instance learning E Schwab, GO Cula, K Standish, SSF Yip, A Stojmirovic, L Ghanem, ... Computer Methods in Biomechanics and Biomedical Engineering: Imaging …, 2022 | 16 | 2022 |
IL-3 and oncogenic Abl regulate the myeloblast transcriptome by altering mRNA stability J Ernst, L Ghanem, Z Bar-Joseph, M McNamara, J Brown, RA Steinman PLoS One 4 (10), e7469, 2009 | 16 | 2009 |
Deep learning models capture histological disease activity in Crohn’s disease and ulcerative colitis with high fidelity D Rymarczyk, W Schultz, A Borowa, JR Friedman, T Danel, P Branigan, ... Journal of Crohn's and Colitis 18 (4), 604-614, 2024 | 15 | 2024 |
RNA-binding proteins PCBP1 and PCBP2 are critical determinants of murine erythropoiesis X Ji, A Jha, J Humenik, LR Ghanem, A Kromer, C Duncan-Lewis, ... Molecular and Cellular Biology 41 (9), e00668-20, 2021 | 13 | 2021 |
CYP11B1 variants influence skeletal maturation via alternative splicing O Grgic, MR Gazzara, A Chesi, C Medina-Gomez, DL Cousminer, ... Communications Biology 4 (1), 1274, 2021 | 5 | 2021 |